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We propose an optimized U-Net architecture for a brain tumor segmentation task in the BraTS21 challenge. To find the optimal model architecture and the learning schedule, we have run an extensive ablation study to test: deep supervision…

Image and Video Processing · Electrical Eng. & Systems 2021-12-28 Michał Futrega , Alexandre Milesi , Michal Marcinkiewicz , Pablo Ribalta

Brain tumors in magnetic resonance imaging (MR) are difficult, time-consuming, and prone to human error. These challenges can be resolved by developing automatic brain tumor segmentation methods from MR images. Various deep-learning models…

Image and Video Processing · Electrical Eng. & Systems 2024-08-23 Subin Sahayam , John Michael Sujay Zakkam , Yoga Sri Varshan , Umarani Jayaraman

This article presents a convolutional neural network for the automatic segmentation of brain tumors in multimodal 3D MR images based on a U-net architecture.We evaluate the use of a densely connected convolutional network encoder (DenseNet)…

Computer Vision and Pattern Recognition · Computer Science 2018-11-20 Jean Stawiaski

Recent advances in deep learning have significantly improved brain tumour segmentation techniques; however, the results still lack confidence and robustness as they solely consider image data without biophysical priors or pathological…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Lipei Zhang , Yanqi Cheng , Lihao Liu , Carola-Bibiane Schönlieb , Angelica I Aviles-Rivero

Glioblastoma is one of the most aggressive and common brain tumors, with a median survival of 10-15 months. Predicting Overall Survival (OS) is critical for personalizing treatment strategies and aligning clinical decisions with patient…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yin Lin , Riccardo Barbieri , Domenico Aquino , Giuseppe Lauria , Marina Grisoli , Elena De Momi , Alberto Redaelli , Simona Ferrante

Convolutional Neural Networks (CNN) have emerged as powerful tools for learning discriminative image features. In this paper, we propose a framework of 3-D fully CNN models for Glioblastoma segmentation from multi-modality MRI data. By…

Computer Vision and Pattern Recognition · Computer Science 2016-11-15 Darvin Yi , Mu Zhou , Zhao Chen , Olivier Gevaert

DNA microarray technology enables the simultaneous measurement of expression levels of thousands of genes, thereby facilitating the understanding of the molecular mechanisms underlying complex diseases such as brain tumors and the…

Machine Learning · Computer Science 2025-08-29 Emine Akpinar , Batuhan Hangun , Murat Oduncuoglu , Oguz Altun , Onder Eyecioglu , Zeynel Yalcin

Gliomas are the most common malignant brain tumors that are treated with chemoradiotherapy and surgery. Magnetic Resonance Imaging (MRI) is used by radiotherapists to manually segment brain lesions and to observe their development…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Jonas Wacker , Marcelo Ladeira , José Eduardo Vaz Nascimento

The significant molecular and pathological heterogeneity of glioblastoma, an aggressive brain tumor, complicates diagnosis and patient stratification. While traditional histopathological assessment remains the standard, deep learning offers…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Juexin Zhang , Qifeng Zhong , Ying Weng , Ke Chen

Cancer is an abnormal growth with potential to invade locally and metastasize to distant organs. Accurate auto-segmentation of the tumor and surrounding normal tissues is required for radiotherapy treatment plan optimization. Recent…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Syed Haider Ali , Asrar Ahmad , Muhammad Ali , Asifullah Khan , Nadeem Shaukat

We propose a method for extracting physics-based biomarkers from a single multiparametric Magnetic Resonance Imaging (mpMRI) scan bearing a glioma tumor. We account for mass effect, the deformation of brain parenchyma due to the growing…

Brain tumor segmentation is a critical task in medical image analysis, aiding in the diagnosis and treatment planning of brain tumor patients. The importance of automated and accurate brain tumor segmentation cannot be overstated. It…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Muhammad Ansab Butt , Absaar Ul Jabbar

Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ramy A. Zeineldin , Mohamed E. Karar , Oliver Burgert , Franziska Mathis-Ullrich

Brain tumors are among the deadliest diseases in the world. Magnetic Resonance Imaging (MRI) is one of the most effective ways to detect brain tumors. Accurate detection of brain tumors based on MRI scans is critical, as it can potentially…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Xiaoyi Liu , Zhuoyue Wang

The application of Deep Learning (DL) for medical diagnosis is often hampered by two problems. First, the amount of training data may be scarce, as it is limited by the number of patients who have acquired the condition to be diagnosed.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-17 Diyuan Lu , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Paul Valery Nguezet , Elie Tagne Fute , Yusuf Brima , Benoit Martin Azanguezet , Marcellin Atemkeng

Brain tumors are one of the deadliest forms of cancer with a mortality rate of over 80%. A quick and accurate diagnosis is crucial to increase the chance of survival. However, in medical analysis, the manual annotation and segmentation of a…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Zachary Schwehr , Sriman Achanta

The optimal treatment strategy of newly diagnosed glioma is strongly influenced by tumour malignancy. Manual non-invasive grading based on MRI is not always accurate and biopsies to verify diagnosis negatively impact overall survival. In…

Image and Video Processing · Electrical Eng. & Systems 2019-08-08 Milan Decuyper , Roel Van Holen

Breast Ultrasound plays a vital role in cancer diagnosis as a non-invasive approach with cost-effective. In recent years, with the development of deep learning, many CNN-based approaches have been widely researched in both tumor…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Dat T. Chung , Minh-Anh Dang , Mai-Anh Vu , Minh T. Nguyen , Thanh-Huy Nguyen , Vinh Q. Dinh

The study explores Artificial Intelligence (AI) powered modeling to predict the evolution of cancer tumor cells in mice under different forms of treatment. The AI models are analyzed against varying ambient and systemic parameters, e.g.…

Biological Physics · Physics 2024-08-12 Amit K Chattopadhyay , Aimee Pascaline N Unkundiye , Gillian Pearce , Steven Russell