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Current treatment planning of patients diagnosed with a brain tumor, such as glioma, could significantly benefit by accessing the spatial distribution of tumor cell concentration. Existing diagnostic modalities, e.g. magnetic resonance…

A U-Net based deep learning architecture is designed to segment brain tumors as they appear on various MRI modalities. Special emphasis is lent to the non-enhancing tumor compartment. The latter has not been considered anymore in recent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 T. Schaffer , A. Brawanski , S. Wein , A. M. Tomé , E. W. Lang

Brain tumor segmentation plays a crucial role in computer-aided diagnosis. This study introduces a novel segmentation algorithm utilizing a modified nnU-Net architecture. Within the nnU-Net architecture's encoder section, we enhance…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Sahaj K. Mistry , Sourav Saini , Aashray Gupta , Aayush Gupta , Sunny Rai , Vinit Jakhetiya , Ujjwal Baid , Sharath Chandra Guntuku

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Antonio Curci , Andrea Esposito

Cancer remains one of the leading causes of mortality worldwide, and among its many forms, brain tumors are particularly notorious due to their aggressive nature and the critical challenges involved in early diagnosis. Recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2025-04-21 Mohammad Mahdi Danesh Pajouh

Accurate detection and segmentation of brain tumors in magnetic resonance imaging (MRI) are critical for effective diagnosis and treatment planning. Despite advances in convolutional neural networks (CNNs) such as U-Net, existing models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Sashank Makanaboyina

Brain tumors, particularly glioblastoma, continue to challenge medical diagnostics and treatments globally. This paper explores the application of deep learning to multi-modality magnetic resonance imaging (MRI) data for enhanced brain…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Chiranjeewee Prasad Koirala , Sovesh Mohapatra , Advait Gosai , Gottfried Schlaug

We present a 3D fully-automatic method for the calibration of partial differential equation (PDE) models of glioblastoma (GBM) growth with mass effect, the deformation of brain tissue due to the tumor. We quantify the mass effect, tumor…

Quantitative Methods · Quantitative Biology 2020-06-18 Shashank Subramanian , Klaudius Scheufele , Naveen Himthani , George Biros

In this paper, we address the crucial task of brain tumor segmentation in medical imaging and propose innovative approaches to enhance its performance. The current state-of-the-art nnU-Net has shown promising results but suffers from…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Tuan-Luc Huynh , Thanh-Danh Le , Tam V. Nguyen , Trung-Nghia Le , Minh-Triet Tran

Brain tumors result from abnormal cell growth in brain tissue. If undiagnosed, they cause neurological deficits, including cognitive impairment, motor dysfunction, and sensory loss. As tumors grow, intracranial pressure increases,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Shravan Venkatraman , Pandiyaraju V , Abeshek A , Aravintakshan S A , Pavan Kumar S , Kannan A , Madhan S

Accurate segmentation of different sub-regions of gliomas including peritumoral edema, necrotic core, enhancing and non-enhancing tumor core from multimodal MRI scans has important clinical relevance in diagnosis, prognosis and treatment of…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Xue Feng , Nicholas Tustison , Craig Meyer

Deep convolutional neural networks (CNNs) have become an essential tool in the medical imaging-based computer-aided diagnostic pipeline. However, training accurate and reliable CNNs requires large fine-grain annotated datasets. To alleviate…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Sajith Rajapaksa , Farzad Khalvati

We discuss solution algorithms for calibrating a tumor growth model using imaging data posed as a deterministic inverse problem. The forward model consists of a nonlinear and time-dependent reaction-diffusion partial differential equation…

Computational Engineering, Finance, and Science · Computer Science 2023-02-17 Baoshan Liang , Luke Lozenski , Umberto Villa , Danial Faghihi

Brain tumors represent one of the most critical neurological conditions, where early and accurate diagnosis is directly correlated with patient survival rates. Manual interpretation of Magnetic Resonance Imaging (MRI) scans is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Chinedu Emmanuel Mbonu , Tochukwu Sunday Belonwu , Okwuchukwu Ejike Chukwuogo , Kenechukwu Sylvanus Anigbogu

In the clinical diagnosis and treatment of brain tumors, manual image reading consumes a lot of energy and time. In recent years, the automatic tumor classification technology based on deep learning has entered people's field of vision.…

Image and Video Processing · Electrical Eng. & Systems 2021-04-07 Yuhao Zhang , Shuhang Wang , Haoxiang Wu , Kejia Hu , Shufan Ji

This study deliberates on the application of advanced AI techniques for brain tumor classification through MRI, wherein the training includes the present best deep learning models to enhance diagnosis accuracy and the potential of usability…

Brain tumor is one of the leading causes of cancer-related death globally among children and adults. Precise classification of brain tumor grade (low-grade and high-grade glioma) at early stage plays a key role in successful prognosis and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Ruqian Hao , Khashayar Namdar , Lin Liu , Farzad Khalvati

Brain tumor diagnosis is a challenging task for clinicians in the modern world. Among the major reasons for cancer-related death is the brain tumor. Gliomas, a category of central nervous system (CNS) tumors, encompass diverse subregions.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Kiranmayee Janardhan , Christy Bobby T

The ability to estimate how a tumor might evolve in the future could have tremendous clinical benefits, from improved treatment decisions to better dose distribution in radiation therapy. Recent work has approached the glioma growth…

Glioblastomas are the most aggressive type of glioma, having a 5-year survival rate of 6.9%. Treatment typically involves surgery, followed by radiotherapy and chemotherapy, and frequent magnetic resonance imaging (MRI) scans to monitor…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Ana Matoso , Catarina Passarinho , Marta P. Loureiro , José Maria Moreira , Patrícia Figueiredo , Rita G. Nunes
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