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Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Diffusion Probabilistic Models stand as a critical tool in generative modelling, enabling the generation of complex data distributions. This family of generative models yields record-breaking performance in tasks such as image synthesis,…

Diffusion models learn to denoise data and the trained denoiser is then used to generate new samples from the data distribution. In this paper, we revisit the diffusion sampling process and identify a fundamental cause of sample quality…

Machine Learning · Computer Science 2024-11-05 Yunshu Wu , Yingtao Luo , Xianghao Kong , Evangelos E. Papalexakis , Greg Ver Steeg

Diffusion Probabilistic Models have demonstrated remarkable performance across a wide range of generative tasks. However, we have observed that these models often suffer from a Signal-to-Noise Ratio-timestep (SNR-t) bias. This bias refers…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Meng Yu , Lei Sun , Jianhao Zeng , Xiangxiang Chu , Kun Zhan

Deep generative models are key-enabling technology to computer vision, text generation, and large language models. Denoising diffusion probabilistic models (DDPMs) have recently gained much attention due to their ability to generate diverse…

Quantum Physics · Physics 2026-02-02 Bingzhi Zhang , Peng Xu , Xiaohui Chen , Quntao Zhuang

Denoising diffusion probabilistic models (DDPMs) have recently achieved leading performances in many generative tasks. However, the inherited iterative sampling process costs hinder their applications to text-to-speech deployment. Through…

Audio and Speech Processing · Electrical Eng. & Systems 2022-07-14 Rongjie Huang , Zhou Zhao , Huadai Liu , Jinglin Liu , Chenye Cui , Yi Ren

Diffusion models have received wide attention in generation tasks. However, the expensive computation cost prevents the application of diffusion models in resource-constrained scenarios. Quantization emerges as a practical solution that…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Weilun Feng , Haotong Qin , Chuanguang Yang , Zhulin An , Libo Huang , Boyu Diao , Fei Wang , Renshuai Tao , Yongjun Xu , Michele Magno

The denoising process of diffusion models can be interpreted as an approximate projection of noisy samples onto the data manifold. Moreover, the noise level in these samples approximates their distance to the underlying manifold. Building…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Abulikemu Abuduweili , Chenyang Yuan , Changliu Liu , Frank Permenter

Diffusion models have marked a significant breakthrough in the synthesis of semantically coherent images. However, their extensive noise estimation networks and the iterative generation process limit their wider application, particularly on…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Yuzhe Yao , Feng Tian , Jun Chen , Haonan Lin , Guang Dai , Yong Liu , Jingdong Wang

Denoising diffusion probabilistic models (DDPM) are a class of generative models which have recently been shown to produce excellent samples. We show that with a few simple modifications, DDPMs can also achieve competitive log-likelihoods…

Machine Learning · Computer Science 2021-02-22 Alex Nichol , Prafulla Dhariwal

In this work, we address the challenge of multi-task image generation with limited data for denoising diffusion probabilistic models (DDPM), a class of generative models that produce high-quality images by reversing a noisy diffusion…

Machine Learning · Computer Science 2023-11-29 Delaram Pirhayatifard , Mohammad Taha Toghani , Guha Balakrishnan , César A. Uribe

Diffusion probabilistic models (DPMs) and their extensions have emerged as competitive generative models yet confront challenges of efficient sampling. We propose a new bilateral denoising diffusion model (BDDM) that parameterizes both the…

Audio and Speech Processing · Electrical Eng. & Systems 2022-03-28 Max W. Y. Lam , Jun Wang , Dan Su , Dong Yu

Diffusion Probabilistic Models (DPMs) have emerged as a powerful class of deep generative models, achieving remarkable performance in image synthesis tasks. However, these models face challenges in terms of widespread adoption due to their…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Kidist Amde Mekonnen , Nicola Dall'Asen , Paolo Rota

Post-training quantization (PTQ) is a neural network compression technique that converts a full-precision model into a quantized model using lower-precision data types. Although it can help reduce the size and computational cost of deep…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Jiawei Liu , Lin Niu , Zhihang Yuan , Dawei Yang , Xinggang Wang , Wenyu Liu

Diffusion models excel in image generation but are computational and resource-intensive due to their reliance on iterative Markov chain processes, leading to error accumulation and limiting the effectiveness of naive compression techniques.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Beomseok Ko , Hyeryung Jang

Generative modeling aims to produce new random examples from an unknown target distribution, given access to a finite collection of examples. Among the leading approaches, denoising diffusion probabilistic models (DDPMs) construct such…

Machine Learning · Statistics 2025-06-12 Vahan Arsenyan , Elen Vardanyan , Arnak Dalalyan

Text-to-image generation via Stable Diffusion models (SDM) have demonstrated remarkable capabilities. However, their computational intensity, particularly in the iterative denoising process, hinders real-time deployment in latency-sensitive…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Shuaiting Li , Juncan Deng , Zeyu Wang , Kedong Xu , Rongtao Deng , Hong Gu , Haibin Shen , Kejie Huang

Diffusion models (DMs) generate remarkable high quality images via the stochastic denoising process, which unfortunately incurs high sampling time. Post-quantizing the trained diffusion models in fixed bit-widths, e.g., 4 bits on weights…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Rocco Manz Maruzzelli , Basile Lewandowski , Lydia Y. Chen

Diffusion models have recently exhibited remarkable abilities to synthesize striking image samples since the introduction of denoising diffusion probabilistic models (DDPMs). Their key idea is to disrupt images into noise through a fixed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zijian Zhang , Zhou Zhao , Jun Yu , Qi Tian

We propose residual denoising diffusion models (RDDM), a novel dual diffusion process that decouples the traditional single denoising diffusion process into residual diffusion and noise diffusion. This dual diffusion framework expands the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Jiawei Liu , Qiang Wang , Huijie Fan , Yinong Wang , Yandong Tang , Liangqiong Qu