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Quantum machine learning offers a promising new paradigm for computational biology by leveraging quantum mechanical principles to enhance cancer classification, biomarker discovery, and bioinformatics diagnostics. In this study, we apply…

Genomics · Quantitative Biology 2026-04-22 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Humaira Gowher , Sabre Kais

Lung cancer has been one of the major threats across the world with the highest mortalities. Computer-aided detection (CAD) can help in early detection and thus can help increase the survival rate. Accurate lung parenchyma segmentation (to…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Muhammad Abdullah , Furqan Shaukat

Accurate tumor staging in lung cancer is crucial for prognosis and treatment planning and is governed by explicit anatomical criteria under fixed guidelines. However, most existing deep learning approaches treat this spatially structured…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Saniah Kayenat Chowdhury , Rusab Sarmun , Muhammad E. H. Chowdhury , Sohaib Bassam Zoghoul , Israa Al-Hashimi , Adam Mushtak , Amith Khandakar

Convolutional neural networks have remarkably progressed the performance of distinguishing plant diseases, severity grading, and nutrition deficiency prediction using leaf images. However, these tasks become more challenging in a realistic…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Asish Bera , Subhajit Roy , Sudiptendu Banerjee

The most common type of lung cancer, lung adenocarcinoma (LUAD), has been increasingly detected since the advent of low-dose computed tomography screening technology. In clinical practice, pre-invasive LUAD (Pre-IAs) should only require…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Jing Zhou , Xiaotong Fu , Xirong Li , Ying Ji

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh

Lung cancer is highly lethal, emphasizing the critical need for early detection. However, identifying lung nodules poses significant challenges for radiologists, who rely heavily on their expertise for accurate diagnosis. To address this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Hossein Jafari , Karim Faez , Hamidreza Amindavar

Lung cancer is the leading cause of cancer death worldwide, and adenocarcinoma (LUAD) is the most common subtype. Exploiting the potential value of the histopathology images can promote precision medicine in oncology. Tissue segmentation is…

In numerous studies, deep learning algorithms have proven their potential for the analysis of histopathology images, for example, for revealing the subtypes of tumors or the primary origin of metastases. These models require large datasets…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Jonathan Ganz , Jonas Ammeling , Samir Jabari , Katharina Breininger , Marc Aubreville

Lung cancer, a malignancy originating in lung tissues, is commonly diagnosed and classified using medical imaging techniques, particularly computed tomography (CT). Despite the integration of machine learning and deep learning methods, the…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Olajumoke O. Adekunle , Joseph D. Akinyemi , Khadijat T. Ladoja , Olufade F. W. Onifade

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Cancer of unknown primary (CUP) is an enigmatic group of diagnoses where the primary anatomical site of tumor origin cannot be determined. This poses a significant challenge since modern therapeutics such as chemotherapy regimen and immune…

Tissues and Organs · Quantitative Biology 2021-07-14 Ming Y. Lu , Melissa Zhao , Maha Shady , Jana Lipkova , Tiffany Y. Chen , Drew F. K. Williamson , Faisal Mahmood

High-resolution full lung CT scans now enable the detailed segmentation of airway trees up to the 6th branching generation. The airway binary masks display very complex tree structures that may encode biological information relevant to…

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

Automatic pulmonary nodules classification is significant for early diagnosis of lung cancers. Recently, deep learning techniques have enabled remarkable progress in this field. However, these deep models are typically of high computational…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Hanliang Jiang , Fuhao Shen , Fei Gao , Weidong Han

The current cancer treatment practice collects multimodal data, such as radiology images, histopathology slides, genomics and clinical data. The importance of these data sources taken individually has fostered the recent raise of radiomics…

Machine Learning · Computer Science 2023-06-16 Matteo Tortora , Ermanno Cordelli , Rosa Sicilia , Lorenzo Nibid , Edy Ippolito , Giuseppe Perrone , Sara Ramella , Paolo Soda

Identification of precancerous polyps during routine colonoscopy screenings is vital for their excision, lowering the risk of developing colorectal cancer. Advanced deep learning algorithms enable precise adenoma classification and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Aqsa Sultana , Nordin Abouzahra , Ahmed Rahu , Brian Shula , Brandon Combs , Derrick Forchetti , Theus Aspiras , Vijayan K. Asari

Lung cancer is one of the most deadly diseases in the world. Detecting such tumors at an early stage can be a tedious task. Existing deep learning architecture for lung nodule identification used complex architecture with large number of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Shah B. Shrey , Lukman Hakim , Muthusubash Kavitha , Hae Won Kim , Takio Kurita

Lung adenocarcinoma (LUAD) is characterized by substantial genetic heterogeneity, posing challenges in identifying reliable biomarkers for improved diagnosis and treatment. Tumor Mutational Burden (TMB) has traditionally been regarded as a…

Applications · Statistics 2024-11-08 Shaofei Zhao , Siming Huang , Kexuan Li , Weiyu Zhou , Lingli Yang , Shige Wang

The field of Machine Learning, a subset of Artificial Intelligence, has led to remarkable advancements in many areas, including medicine. Machine Learning algorithms require large datasets to train computer models successfully. Although…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Andrew A. Borkowski , Marilyn M. Bui , L. Brannon Thomas , Catherine P. Wilson , Lauren A. DeLand , Stephen M. Mastorides