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Graph Transformers (GTs) facilitate the comprehension of graph-structured data by calculating the self-attention of node pairs without considering node position information. To address this limitation, we introduce an innovative and…
Genetic mutations can cause disease by disrupting normal gene function. Identifying the disease-causing mutations from millions of genetic variants within an individual patient is a challenging problem. Computational methods which can…
Bone metastasis analysis is a significant challenge in pathology and plays a critical role in determining patient quality of life and treatment strategies. The microenvironment and specific tissue structures are essential for pathologists…
Accurate classification of cancer-related biomedical abstracts is critical for advancing cancer informatics and supporting decision-making in healthcare research. Yet progress in this domain is often constrained by limited availability of…
Contemporary glioma diagnosis integrates molecular features with histopathology to guide clinical decision-making. However, in clinical settings, divergent imaging protocols result in incomplete MRI sequences, leading to two primary…
Community detection is crucial for applications like targeted marketing and recommendation systems. Traditional methods rely on network structure, and embedding-based models integrate semantic information. However, there is a challenge when…
Inspired by the successful application of contrastive learning on graphs, researchers attempt to impose graph contrastive learning approaches on heterogeneous information networks. Orthogonal to homogeneous graphs, the types of nodes and…
MiRNAs, due to their role in gene regulation, have paved a new pathway for pharmacology, focusing on drug development that targets miRNAs. However, traditional wet lab experiments are limited by efficiency and cost constraints, making it…
Comorbidity carries significant implications for disease understanding and management. The genetic causes for comorbidity often trace back to mutations occurred either in the same gene associated with two diseases or in different genes…
Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…
Graph transformer networks (GTN) are a variant of graph convolutional networks (GCN) that are targeted to heterogeneous graphs in which nodes and edges have associated type information that can be exploited to improve inference accuracy.…
The widespread application of machine learning techniques to biomedical data has produced many new insights into disease progression and improving clinical care. Inspired by the flexibility and interpretability of graphs (networks), as well…
Accurate trajectory prediction is crucial for ensuring safe and efficient autonomous driving. However, most existing methods overlook complex interactions between traffic participants that often govern their future trajectories. In this…
The prosperous development of e-commerce has spawned diverse recommendation systems. As a matter of fact, there exist rich and complex interactions among various types of nodes in real-world recommendation systems, which can be constructed…
Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene…
In the treatment of complex diseases, treatment regimens using a single drug often yield limited efficacy and can lead to drug resistance. In contrast, combination drug therapies can significantly improve therapeutic outcomes through…
Generative self-supervised learning (SSL), especially masked autoencoders, has become one of the most exciting learning paradigms and has shown great potential in handling graph data. However, real-world graphs are always heterogeneous,…
Transformer and its variants have been widely used for medical image segmentation. However, the large number of parameter and computational load of these models make them unsuitable for mobile health applications. To address this issue, we…
In autonomous driving, accurately interpreting the movements of other road users and leveraging this knowledge to forecast future trajectories is crucial. This is typically achieved through the integration of map data and tracked…
Polygonal meshes have become the standard for discretely approximating 3D shapes, thanks to their efficiency and high flexibility in capturing non-uniform shapes. This non-uniformity, however, leads to irregularity in the mesh structure,…