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The timely detection of disease outbreaks through reliable early warning signals (EWSs) is indispensable for effective public health mitigation strategies. Nevertheless, the intricate dynamics of real-world disease spread, often influenced…

Machine Learning · Computer Science 2024-03-26 Amit K. Chakraborty , Shan Gao , Reza Miry , Pouria Ramazi , Russell Greiner , Mark A. Lewis , Hao Wang

Methods to detect the emergence of infectious diseases, and approach to the "critical transition" RE = 1, have to potential to avert substantial disease burden by facilitating preemptive actions like vaccination campaigns. Early warning…

Other Quantitative Biology · Quantitative Biology 2025-04-16 Callum R. K. Arnold , Matthew J. Ferrari

Many natural and man-made systems are prone to critical transitions -- abrupt and potentially devastating changes in dynamics. Deep learning classifiers can provide an early warning signal (EWS) for critical transitions by learning generic…

Quantitative Methods · Quantitative Biology 2024-02-12 Thomas M. Bury , Daniel Dylewsky , Chris T. Bauch , Madhur Anand , Leon Glass , Alvin Shrier , Gil Bub

Recent advances in deep learning (DL) have prompted the development of high-performing early warning score (EWS) systems, predicting clinical deteriorations such as acute kidney injury, acute myocardial infarction, or circulatory failure.…

Machine Learning · Computer Science 2025-02-05 Yuxiao Cheng , Xinxin Song , Ziqian Wang , Qin Zhong , Kunlun He , Jinli Suo

Providing accurate and reliable predictions about the future of an epidemic is an important problem for enabling informed public health decisions. Recent works have shown that leveraging data-driven solutions that utilize advances in deep…

Machine Learning · Computer Science 2023-11-21 Harshavardhan Kamarthi , B. Aditya Prakash

Dryland vegetation ecosystems are known to be susceptible to critical transitions between alternative stable states when subjected to external forcing. Such transitions are often discussed through the framework of bifurcation theory, but…

Computational Physics · Physics 2025-05-16 Daniel Dylewsky , Sonia Kéfi , Madhur Anand , Chris T. Bauch

Early warning systems (EWSs) are critical for forecasting and preventing economic and financial crises. EWSs are designed to provide early warning signs of financial troubles, allowing policymakers and market participants to intervene…

General Finance · Quantitative Finance 2023-10-03 Ali Namaki , Reza Eyvazloo , Shahin Ramtinnia

Real-life systems often experience regime shifts. An early warning signal (EWS) is a quantity that attempts to anticipate such a regime shift. Because complex systems of practical interest showing regime shifts are often dynamics on…

Physics and Society · Physics 2025-05-23 Shilong Yu , Neil G. MacLaren , Naoki Masuda

Infectious diseases remain among the top contributors to human illness and death worldwide, among which many diseases produce epidemic waves of infection. The unavailability of specific drugs and ready-to-use vaccines to prevent most of…

Machine Learning · Computer Science 2023-07-18 Madhurima Panja , Tanujit Chakraborty , Uttam Kumar , Nan Liu

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

The development of robust Early Warning Signals (EWS) is necessary to quantify the risk of crossing tipping points in the present-day climate change. Classically, EWS are statistical measures based on time series of climate state variables,…

Atmospheric and Oceanic Physics · Physics 2025-03-25 Laure Moinat , Jérôme Kasparian , Maura Brunetti

Early warning for epilepsy patients is crucial for their safety and well-being, in particular to prevent or minimize the severity of seizures. Through the patients' EEG data, we propose a meta learning framework to improve the prediction of…

Machine Learning · Computer Science 2024-01-12 Peng Zhang , Ting Gao , Jin Guo , Jinqiao Duan , Sergey Nikolenko

Continual learning, the ability of a model to learn over time without forgetting previous knowledge and, therefore, be adaptive to new data, is paramount in dynamic fields such as disease outbreak prediction. Deep neural networks, i.e.,…

Machine Learning · Computer Science 2024-01-18 Saba Aslam , Abdur Rasool , Hongyan Wu , Xiaoli Li

Forecasting the occurrence and absence of novel disease outbreaks is essential for disease management. Here, we develop a general model, with no real-world training data, that accurately forecasts outbreaks and non-outbreaks. We propose a…

Machine Learning · Computer Science 2024-04-16 Shan Gao , Amit K. Chakraborty , Russell Greiner , Mark A. Lewis , Hao Wang

Seizure forecasting may provide patients with timely warnings to adapt their daily activities and help clinicians deliver more objective, personalized treatments. While recent work has convincingly demonstrated that seizure risk assessment…

Neurons and Cognition · Quantitative Biology 2019-06-10 Christian Meisel , Rima El Atrache , Michele Jackson , Sarah Schubach , Claire Ufongene , Tobias Loddenkemper

Bank crisis is challenging to define but can be manifested through bank contagion. This study presents a comprehensive framework grounded in nonlinear time series analysis to identify potential early warning signals (EWS) for impending…

Risk Management · Quantitative Finance 2023-10-17 Shijia Song , Handong Li

In the wake of the SARS-CoV-2 pandemic, there has been heightened interest from applied mathematicians in infectious disease modelling. Modelling efforts often focus on predicting whether diseases are likely to be eliminated or, instead,…

Populations and Evolution · Quantitative Biology 2026-01-22 Joshua Looker , Kat S. Rock , Louise Dyson

Pandemic outbreaks such as COVID-19 occur unexpectedly, and need immediate action due to their potential devastating consequences on global health. Point-of-care routine assessments such as electrocardiogram (ECG), can be used to develop…

Signal Processing · Electrical Eng. & Systems 2023-01-12 Weijie Sun , Sunil Vasu Kalmady , Nariman Sepehrvand , Luan Manh Chu , Zihan Wang , Amir Salimi , Abram Hindle , Russell Greiner , Padma Kaul

The early detection of infectious disease outbreaks is a crucial task to protect population health. To this end, public health surveillance systems have been established to systematically collect and analyse infectious disease data. A…

Applications · Statistics 2019-02-27 Benedikt Zacher , Irina Czogiel

Large-scale outbreaks of epidemics, misinformation, or other harmful contagions pose significant threats to human society, yet the fundamental question of whether an emerging outbreak will escalate into a major epidemic or naturally die out…

Social and Information Networks · Computer Science 2025-10-07 Wenchao He , Tao Jia
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