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Difficult-to-treat depression (DTD) has been proposed as a broader and more clinically comprehensive perspective on a person's depressive disorder where despite treatment, they continue to experience significant burden. We sought to develop…

Computation and Language · Computer Science 2024-02-13 Isabelle Lorge , Dan W. Joyce , Niall Taylor , Alejo Nevado-Holgado , Andrea Cipriani , Andrey Kormilitzin

We propose DISC-LawLLM, an intelligent legal system utilizing large language models (LLMs) to provide a wide range of legal services. We adopt legal syllogism prompting strategies to construct supervised fine-tuning datasets in the Chinese…

Computation and Language · Computer Science 2023-09-26 Shengbin Yue , Wei Chen , Siyuan Wang , Bingxuan Li , Chenchen Shen , Shujun Liu , Yuxuan Zhou , Yao Xiao , Song Yun , Xuanjing Huang , Zhongyu Wei

Mental health risk is a critical global public health challenge, necessitating innovative and reliable assessment methods. With the development of large language models (LLMs), they stand out to be a promising tool for explainable mental…

Artificial Intelligence · Computer Science 2025-05-21 Xinzhe Zheng , Sijie Ji , Jiawei Sun , Renqi Chen , Wei Gao , Mani Srivastava

Matching patients to clinical trials is a key unsolved challenge in bringing new drugs to market. Today, identifying patients who meet a trial's eligibility criteria is highly manual, taking up to 1 hour per patient. Automated screening is…

Computation and Language · Computer Science 2024-04-11 Michael Wornow , Alejandro Lozano , Dev Dash , Jenelle Jindal , Kenneth W. Mahaffey , Nigam H. Shah

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

As mental health issues continue to rise globally, there is an increasing demand for accessible and scalable therapeutic solutions. Many individuals currently seek support from Large Language Models (LLMs), even though these models have not…

Computation and Language · Computer Science 2026-03-05 Navdeep Singh Bedi , Ana-Maria Bucur , Noriko Kando , Fabio Crestani

Large language models (LLMs) have demonstrated remarkable performance on various medical benchmarks, but their capabilities across different cognitive levels remain underexplored. Inspired by Bloom's Taxonomy, we propose a…

Computation and Language · Computer Science 2025-06-11 Yuxuan Zhou , Xien Liu , Chenwei Yan , Chen Ning , Xiao Zhang , Boxun Li , Xiangling Fu , Shijin Wang , Guoping Hu , Yu Wang , Ji Wu

The global mental health crisis is looming with a rapid increase in mental disorders, limited resources, and the social stigma of seeking treatment. As the field of artificial intelligence (AI) has witnessed significant advancements in…

Computation and Language · Computer Science 2023-11-27 Neo Christopher Chung , George Dyer , Lennart Brocki

Transforming a dynamic hypothesis into a causal loop diagram (CLD) is crucial for System Dynamics Modelling. Extracting key variables and causal relationships from text to build a CLD is often challenging and time-consuming for novice…

Machine Learning · Computer Science 2025-03-31 Ning-Yuan Georgia Liu , David R. Keith

As the prevalence of mental health challenges, social media has emerged as a key platform for individuals to express their emotions.Deep learning tends to be a promising solution for analyzing mental health on social media. However, black…

Computation and Language · Computer Science 2024-10-15 Wei Zhai , Nan Bai , Qing Zhao , Jianqiang Li , Fan Wang , Hongzhi Qi , Meng Jiang , Xiaoqin Wang , Bing Xiang Yang , Guanghui Fu

LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…

Human-Computer Interaction · Computer Science 2025-08-26 Mithat Can Ozgun , Jiahuan Pei , Koen Hindriks , Lucia Donatelli , Qingzhi Liu , Junxiao Wang

Recent advancements in large language models (LLMs) promise to expand mental health interventions by emulating therapeutic techniques, potentially easing barriers to care. Yet there is a lack of real-world empirical evidence evaluating the…

Human-Computer Interaction · Computer Science 2025-01-28 Yinzhou Wang , Yimeng Wang , Ye Xiao , Liabette Escamilla , Bianca Augustine , Kelly Crace , Gang Zhou , Yixuan Zhang

Cognitive Diagnosis (CD) has become a critical task in AI-empowered education, supporting personalized learning by accurately assessing students' cognitive states. However, traditional CD models often struggle in cold-start scenarios due to…

Computation and Language · Computer Science 2025-05-28 Yu He , Zihan Yao , Chentao Song , Tianyu Qi , Jun Liu , Ming Li , Qing Huang

Reasoning Large Language Models (LLMs) with enhanced accuracy and explainability are increasingly being adopted in the medical domain, as the life-critical nature of clinical decision-making demands reliable support. Despite these…

Computation and Language · Computer Science 2025-11-12 Sung-Min Lee , Siyoon Lee , Juyeon Kim , Kyoungmin Roh

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser

We introduce Concept Bottleneck Large Language Models (CB-LLMs), a novel framework for building inherently interpretable Large Language Models (LLMs). In contrast to traditional black-box LLMs that rely on limited post-hoc interpretations,…

Computation and Language · Computer Science 2025-09-09 Chung-En Sun , Tuomas Oikarinen , Berk Ustun , Tsui-Wei Weng

The rise of Large Language Models (LLMs), such as LLaMA and ChatGPT, has opened new opportunities for enhancing recommender systems through improved explainability. This paper provides a systematic literature review focused on leveraging…

Information Retrieval · Computer Science 2025-01-22 Alan Said

Despite the rapid expansion of Large Language Models (LLMs) in healthcare, robust and explainable evaluation of their ability to assess clinical trial reporting according to CONSORT standards remains an open challenge. In particular,…

Artificial Intelligence · Computer Science 2026-02-26 Sohyeon Jeon , Hyung-Chul Lee