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In spite of the strong performance of machine learning (ML) models in radiology, they have not been widely accepted by radiologists, limiting clinical integration. A key reason is the lack of explainability, which ensures that model…

Human-Computer Interaction · Computer Science 2026-04-14 Sara Ketabi , Matthias W. Wagner , Birgit Betina Ertl-Wagner , Greg A. Jamieson , Farzad Khalvati

Stochastic processes provide a mathematically elegant way model complex data. In theory, they provide flexible priors over function classes that can encode a wide range of interesting assumptions. In practice, however, efficient inference…

Machine Learning · Computer Science 2022-09-15 Swapnil Mishra , Seth Flaxman , Tresnia Berah , Harrison Zhu , Mikko Pakkanen , Samir Bhatt

Deploying machine learning models in safety-related do-mains (e.g. autonomous driving, medical diagnosis) demands for approaches that are explainable, robust against adversarial attacks and aware of the model uncertainty. Recent deep…

Computer Vision and Pattern Recognition · Computer Science 2020-12-14 Jan Kronenberger , Anselm Haselhoff

A very active area of materials research is to devise methods that use machine learning to automatically extract predictive models from existing materials data. While prior examples have demonstrated successful models for some applications,…

Materials Science · Physics 2016-08-29 Logan Ward , Ankit Agrawal , Alok Choudhary , Christopher Wolverton

We use machine learning (ML) to infer stress and plastic flow rules using data from repre- sentative polycrystalline simulations. In particular, we use so-called deep (multilayer) neural networks (NN) to represent the two response…

Computational Physics · Physics 2018-09-05 Reese E. Jones , Jeremy A. Templeton , Clay M. Sanders , Jakob T. Ostien

Most existing evaluations of explainable machine learning (ML) methods rely on simplifying assumptions or proxies that do not reflect real-world use cases; the handful of more robust evaluations on real-world settings have shortcomings in…

Machine Learning (ML) has offered innovative perspectives for accelerating the discovery of new functional materials, leveraging the increasing availability of material databases. Despite the promising advances, data-driven methods face…

Machine learning pipeline potentially consists of several stages of operations like data preprocessing, feature engineering and machine learning model training. Each operation has a set of hyper-parameters, which can become irrelevant for…

Machine Learning · Computer Science 2021-05-04 Xudong Sun , Jiali Lin , Bernd Bischl

Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

Machine learning (ML) has become a versatile tool for analyzing anomalous diffusion trajectories, yet most existing pipelines are trained on large collections of simulated data. In contrast, experimental trajectories, such as those from…

Biological Physics · Physics 2025-12-10 Gongyi Wang , Yu Zhang , Zihan Huang

Unraveling the connections between microscopic structure, emergent physical properties, and slow dynamics has long been a challenge when studying the glass transition. The absence of clear visible structural order in amorphous…

What is it to interpret the outputs of an opaque machine learning model. One approach is to develop interpretable machine learning techniques. These techniques aim to show how machine learning models function by providing either model…

Machine Learning · Computer Science 2024-09-06 Andrew Smart , Atoosa Kasirzadeh

In this paper, we present our vision of differentiable ML pipelines called DiffML to automate the construction of ML pipelines in an end-to-end fashion. The idea is that DiffML allows to jointly train not just the ML model itself but also…

Databases · Computer Science 2022-07-06 Benjamin Hilprecht , Christian Hammacher , Eduardo Reis , Mohamed Abdelaal , Carsten Binnig

Deep learning models are widely used across computer vision and other domains. When working on the model induction, selecting the right architecture for a given dataset often relies on repetitive trial-and-error procedures. This procedure…

Machine Learning · Computer Science 2026-01-06 Yen-Chia Chen , Hsing-Kuo Pao , Hanjuan Huang

Machine learning (ML) has seen significant growth in both popularity and importance. The high prediction accuracy of ML models is often achieved through complex black-box architectures that are difficult to interpret. This interpretability…

Machine Learning · Statistics 2024-07-29 David Köhler , David Rügamer , Matthias Schmid

Exploratory analysis of high-dimensional data relies on embedding the data into a low-dimensional space (typically 2D or 3D), based on which visualization plot is produced to uncover meaningful structures and to communicate geometric and…

Human-Computer Interaction · Computer Science 2026-04-23 Burak Susam , Tingting Mu

Machine learning models are primarily judged by predictive performance, especially in applied settings. Once a model reaches high accuracy, its explanation is often assumed to be correct and trustworthy. This assumption raises an overlooked…

Machine Learning · Computer Science 2026-02-12 Chama Bensmail

Mechanistic Interpretability (MI) aims to reverse-engineer model behaviors by identifying functional sub-networks. Yet, the scientific validity of these findings depends on their stability. In this work, we argue that circuit discovery is…

Machine Learning · Computer Science 2026-02-04 Maxime Méloux , François Portet , Maxime Peyrard

Amino acid sequence portrays most intrinsic form of a protein and expresses primary structure of protein. The order of amino acids in a sequence enables a protein to acquire a particular stable conformation that is responsible for the…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , David Fernandez-Baca , Akshay Deepak , Sudhakar Tripathi

Machine learning methods have been remarkably successful for a wide range of application areas in the extraction of essential information from data. An exciting and relatively recent development is the uptake of machine learning in the…

Machine Learning · Computer Science 2020-03-13 Ribana Roscher , Bastian Bohn , Marco F. Duarte , Jochen Garcke