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The reliability of a phylogenetic inference method from genomic sequence data is ensured by its statistical consistency. Bayesian inference methods produce a sample of phylogenetic trees from the posterior distribution given sequence data.…

Metric Geometry · Mathematics 2016-06-10 Alex Gavryushkin , Alexei J. Drummond

Rotation distance between trees measures the number of simple operations it takes to transform one tree into another. There are no known polynomial-time algorithms for computing rotation distance. In the case of ordered rooted trees, we…

Data Structures and Algorithms · Computer Science 2018-03-19 Sean Cleary , Katherine St. John

Merge trees are fundamental structures in topological data analysis. Interleaving distance is a widely accepted metric for comparing merge trees, with applications in visualization and scientific computing. While a greedy algorithm exists…

Computational Geometry · Computer Science 2025-09-22 Elena Farahbakhsh Touli , Talha Bin Masood

Cancers follow a clonal Darwinian evolution, with fitter subclones replacing more quiescent cells, ultimately giving rise to macroscopic disease. High-throughput genomics provides the opportunity to investigate these processes and determine…

Quantitative Methods · Quantitative Biology 2014-10-07 Sakellarios Zairis , Hossein Khiabanian , Andrew J. Blumberg , Raul Rabadan

Phylogenetic trees summarize evolutionary relationships between organisms, and tools to analyze collections of phylogenetic trees enable contrasts between different genes' ancestry. The BHV metric space has enabled the analysis of…

Quantitative Methods · Quantitative Biology 2026-04-24 Maria Alejandra Valdez Cabrera , Amy D Willis

Rotation distance between rooted binary trees is the minimum number of simple rotations needed to transform one tree into the other. Computing the rotation distance between a pair of rooted trees can be quickly reduced in cases where there…

Data Structures and Algorithms · Computer Science 2020-03-05 Sean Cleary , Roland Maio

In phylogenetics, distances are often used to measure the incongruence between a pair of phylogenetic trees that are reconstructed by different methods or using different regions of genome. Motivated by the maximum parsimony principle in…

Populations and Evolution · Quantitative Biology 2016-07-08 Steven Kelk , Mareike Fischer , Vincent Moulton , Taoyang Wu

Rotation distance measures the difference in shape between binary trees of the same size by counting the minimum number of rotations needed to transform one tree to the other. We describe several types of rotation distance where…

Group Theory · Mathematics 2018-03-19 Sean Cleary , Jennifer Taback

We describe a kernel of size 9k-8 for the NP-hard problem of computing the Tree Bisection and Reconnect (TBR) distance k between two unrooted binary phylogenetic trees. We achieve this by extending the existing portfolio of reduction rules…

Data Structures and Algorithms · Computer Science 2022-09-21 Steven Kelk , Simone Linz , Ruben Meuwese

Comparing observed behavior (event data generated during process executions) with modeled behavior (process models), is an essential step in process mining analyses. Alignments are the de-facto standard technique for calculating conformance…

Databases · Computer Science 2021-05-18 Daniel Schuster , Sebastiaan van Zelst , Wil M. P. van der Aalst

Finding a minimum spanning tree (MST) for $n$ points in an arbitrary metric space is a fundamental primitive for hierarchical clustering and many other ML tasks, but this takes $\Omega(n^2)$ time to even approximate. We introduce a…

Data Structures and Algorithms · Computer Science 2025-02-19 Nate Veldt , Thomas Stanley , Benjamin W. Priest , Trevor Steil , Keita Iwabuchi , T. S. Jayram , Geoffrey Sanders

A central theme in phylogenetics is the reconstruction and analysis of evolutionary trees from a given set of data. To determine the optimal search methods for reconstructing trees, it is crucial to understand the size and structure of the…

Populations and Evolution · Quantitative Biology 2016-08-15 Jamie V. de Jong , Jeanette C McLeod , Mike Steel

As well known the rotation distance D(S,T) between two binary trees S, T of n vertices is the minimum number of rotations of pairs of vertices to transform S into T. We introduce the new operation of chain rotation on a tree, involving two…

Data Structures and Algorithms · Computer Science 2012-04-27 Fabrizio Luccio , Linda Pagli

We investigate the complexity of finding a transformation from a given spanning tree in a graph to another given spanning tree in the same graph via a sequence of edge flips. The exchange property of the matroid bases immediately yields…

Data Structures and Algorithms · Computer Science 2022-01-13 Nicolas Bousquet , Takehiro Ito , Yusuke Kobayashi , Haruka Mizuta , Paul Ouvrard , Akira Suzuki , Kunihiro Wasa

Early literature on genome rearrangement modelling views the problem of computing evolutionary distances as an inherently combinatorial one. In particular, attention was given to estimating distances using the minimum number of events…

Populations and Evolution · Quantitative Biology 2023-01-12 Joshua Stevenson , Venta Terauds , Jeremy Sumner

Kondo et al. (DS 2014) proposed methods for computing distances between unordered rooted trees by transforming an instance of the distance computing problem into an instance of the integer programming problem. They showed that the tree edit…

Data Structures and Algorithms · Computer Science 2017-06-13 Eunpyeong Hong , Yasuaki Kobayashi , Akihiro Yamamoto

Ancestral mixture model, proposed by Chen and Lindsay (2006), is an important model to build a hierarchical tree from high dimensional binary sequences. Mixture trees created from ancestral mixture models involve in the inferred…

Data Structures and Algorithms · Computer Science 2019-11-28 Justie Su-Tzu Juan , Yi-Ching Chen , Chen-Hui Lin , Shu-Chuan , Chen

Spanning trees are an important primitive in many data analysis tasks, when a data set needs to be summarized in terms of its "skeleton", or when a tree-shaped graph over all observations is required for downstream processing. Popular…

Discrete Mathematics · Computer Science 2024-04-10 Enrique Fita Sanmartín , Christoph Schnörr , Fred A. Hamprecht

We determine the maximum distance between any two of the center, centroid, and subtree core among trees with a given order. Corresponding results are obtained for trees with given maximum degree and also for trees with given diameter. The…

Combinatorics · Mathematics 2017-01-20 Heather Smith , László Székely , Hua Wang , Shuai Yuan

The structure of an evolving network contains information about its past. Extracting this information efficiently, however, is, in general, a difficult challenge. We formulate a fast and efficient method to estimate the most likely history…

Physics and Society · Physics 2020-09-16 Gábor Timár , Rui A. da Costa , Sergey N. Dorogovtsev , José F. F. Mendes