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In this article we explore the requirements for enabling high quality optically detected magnetic resonance (ODMR) spectroscopy in a conventional gradient force optical tweezers using nanodiamonds containing nitrogen-vacancy (NV$^{-}$)…
Optically accessible spin-active nanomaterials are promising as quantum nanosensors for probing biological samples. However, achieving bioimaging-level brightness and high-quality spin properties for these materials is challenging and…
Deterministic optical manipulation of fluorescent nanodiamonds (FNDs) in fluids has emerged as an experimental challenge in multimodal biological imaging. Designing and developing nano-optical trapping strategies to serve this purpose is an…
Probing electrical and magnetic properties in aqueous environments remains a frontier challenge in nanoscale sensing. Our inability to do so with quantitative accuracy imposes severe limitations, for example, on our understanding of the…
Ensembles of negatively charged nitrogen vacancy centers (NV-) in diamond have been proposed for sensing of magnetic fields and paramagnetic agents, and as a source of spin-order for the hyperpolarization of nuclei in magnetic resonance…
Fluorescent nanodiamonds (fNDs) containing Nitrogen Vacancy (NV) centres are promising candidates for quantum sensing in biological environments. However, to date, there has been little progress made to combine the sensing capabilities of…
The nitrogen-vacancy (NV) center in diamond exists in different charge states with distinct photoluminescence properties, which are sensitive to the nanoscale electrochemical environment. Hence, the NV charge state is emerging as a powerful…
Nitrogen-doped ultrananocrystalline diamond (N-UNCD) is a promising material for a variety of neural interfacing applications, due to its unique combination of high conductivity, bioinertness, and durability. One emerging application for…
Low quantum yields of near infrared (NIR) fluorophores have limited their capabilities as imaging probes in a transparent, low background imaging window. Here for the first time we reported near-infrared fluorescence enhance (NIR-FE) cell…
The near infrared (NIR) region of the electromagnetic spectrum contains valuable information about vibrational overtone and combination modes. Additionally, fluorophores that emit in the NIR are desired because this spectral range falls…
Nitrogen-vacancy (NV) centers show great potentials for nanoscale bio-sensing and bio-imaging. Nevertheless, their envisioned bio-applications suffer from intrinsic background noise due to unavoidable light scattering and autofluorescence…
Diamond nanocrystals containing Nitrogen-Vacancy (NV) color centers have been used in recent years as fluorescent probes for near-field and cellular imaging. In this work we report that an infrared (IR) pulsed excitation beam can quench the…
Infrared (IR) dyes, especially those within the near-infrared (NIR) spectrum, offer substantial advantages for in vivo imaging, owing to their deep tissue penetration and minimal background autofluorescence. Nanoparticles incorporating…
Nanodiamonds containing luminescent point defects are widely explored for applications in quantum bio-sensing such as nanoscale magnetometry, thermometry, and electrometry. A key challenge in the development of such applications is a large…
Fluorescent nanodiamonds are attracting major attention in the field of bio-sensing and biolabeling. In this work we demonstrate a robust approach to surface functionalize individual nanodiamonds with metal-phenolic networks that enhance…
High biocompatibility, variable size ranging from ~ 5 nm, stable luminescence from its color centers and simple carbon chemistry for biomolecule grafting make nanodiamond (ND) particles an attractive alternative to molecular dyes for…
Owing to the unique electronic spin properties, the nitrogen-vacancy (NV) centers hosted in diamond have emerged as a powerful quantum sensor for various physical parameters and biological species. In this work, a miniature optical-fiber…
Compared to imaging in the visible and near-infrared regions below 900 nm, imaging in the second near-infrared window (NIR-II, 1000-1700 nm) is a promising method for deep-tissue high-resolution optical imaging in vivo mainly due to the…
Near-infrared fluorescence imaging offers improved spatial precision by reducing light scattering and absorption in tissue. Despite this key advantage, the NIR region is limited by the availability of fluorophores, most of which exhibit…
The use of diamond color centers such as the nitrogen-vacancy (NV) center is increasingly enabling quantum sensing and computing applications. Novel concepts like cavity coupling and readout, laser threshold magnetometry and multi-pass…