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Protein structure prediction often hinges on multiple sequence alignments (MSAs), which underperform on low-homology and orphan proteins. We introduce PLAME, a lightweight MSA design framework that leverages evolutionary embeddings from…

Machine Learning · Computer Science 2025-09-29 Hanqun Cao , Xinyi Zhou , Zijun Gao , Chenyu Wang , Xin Gao , Zhi Zhang , Cesar de la Fuente-Nunez , Chunbin Gu , Ge Liu , Pheng-Ann Heng

Due to the advantage of achieving a better performance under weak regularization, elastic net has attracted wide attention in statistics, machine learning, bioinformatics, and other fields. In particular, a variation of the elastic net,…

Machine Learning · Statistics 2018-06-14 Xin-Guang Yang , Yongjin Lu

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

Approximate Bayesian computation (ABC) or likelihood-free inference algorithms are used to find approximations to posterior distributions without making explicit use of the likelihood function, depending instead on simulation of sample data…

Computation · Statistics 2015-09-08 Richard D. Wilkinson

Deep learning has redefined the field of artificial intelligence (AI) thanks to the rise of artificial neural networks, which are architectures inspired by their neurological counterpart in the brain. Through the years, this dualism between…

Machine Learning · Computer Science 2023-02-21 Tommaso Salvatori , Yuhang Song , Thomas Lukasiewicz , Rafal Bogacz , Zhenghua Xu

The success of convolutional neural networks (CNNs) in various applications is accompanied by a significant increase in computation and parameter storage costs. Recent efforts to reduce these overheads involve pruning and compressing the…

In this paper, Artificial Bee Colony (ABC) algorithm which inspired from the behavior of honey bees swarm is presented. ABC is a stochastic population-based evolutionary algorithm for problem solving. ABC algorithm, which is considered one…

Computational Engineering, Finance, and Science · Computer Science 2014-02-28 Osman Hegazy , Omar S. Soliman , Mustafa Abdul Salam

A key step in interpreting gas-phase ion mobility coupled with mass spectrometry (IM-MS) data for unknown structure prediction involves identifying the most favorable protonated structure. In the gas phase, the site of protonation is…

Machine Learning · Computer Science 2024-11-28 Hongni Jin , Kenneth M. Merz

The shortage of nephrologists and the growing public health concern over renal failure have spurred the demand for AI systems capable of autonomously detecting kidney abnormalities. Renal failure, marked by a gradual decline in kidney…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Tahmim Hossain , Faisal Sayed , Solehin Islam

A biologically plausible method for training an Artificial Neural Network (ANN) involves treating each unit as a stochastic Reinforcement Learning (RL) agent, thereby considering the network as a team of agents. Consequently, all units can…

Machine Learning · Computer Science 2023-07-26 Stephen Chung

Approximate Bayesian Computation (ABC) methods are increasingly used for inference in situations in which the likelihood function is either computationally costly or intractable to evaluate. Extensions of the basic ABC rejection algorithm…

Computation · Statistics 2020-05-01 Umberto Simola , Jessica Cisewski-Kehe , Michael U. Gutmann , Jukka Corander

While convolutional neural networks (CNN) have achieved impressive performance on various classification/recognition tasks, they typically consist of a massive number of parameters. This results in significant memory requirement as well as…

Computer Vision and Pattern Recognition · Computer Science 2019-05-14 Pravendra Singh , Vinay Kumar Verma , Piyush Rai , Vinay P. Namboodiri

Breast cancer is not preventable because of its unknown causes. However, its early diagnosis increases patients' recovery chances. Machine learning (ML) can be utilized to improve treatment outcomes in healthcare operations while…

Machine Learning · Computer Science 2024-08-09 Kamyab Karimi , Ali Ghodratnama , Reza Tavakkoli-Moghaddam

The field of artificial intelligence faces significant challenges in achieving both biological plausibility and computational efficiency, particularly in visual learning tasks. Current artificial neural networks, such as convolutional…

Machine Learning · Computer Science 2024-09-27 Jacobo Ruiz , Manas Gupta

Approximate Bayesian computation (ABC) is a family of computational techniques in Bayesian statistics. These techniques allow to fi t a model to data without relying on the computation of the model likelihood. They instead require to…

Statistics Theory · Mathematics 2018-12-27 Maxime Lenormand , Franck Jabot , Guillaume Deffuant

Successful motor-imagery brain-computer interface (MI-BCI) algorithms either extract a large number of handcrafted features and train a classifier, or combine feature extraction and classification within deep convolutional neural networks…

Signal Processing · Electrical Eng. & Systems 2020-10-15 Michael Hersche , Luca Benini , Abbas Rahimi

Performing exact posterior inference in complex generative models is often difficult or impossible due to an expensive to evaluate or intractable likelihood function. Approximate Bayesian computation (ABC) is an inference framework that…

Machine Learning · Statistics 2016-02-16 Jovana Mitrovic , Dino Sejdinovic , Yee Whye Teh

Although convolutional neural networks (CNNs) are now widely used in various computer vision applications, its huge resource demanding on parameter storage and computation makes the deployment on mobile and embedded devices difficult.…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Zhe Xu , Ray C. C. Cheung

We present APQ for efficient deep learning inference on resource-constrained hardware. Unlike previous methods that separately search the neural architecture, pruning policy, and quantization policy, we optimize them in a joint manner. To…

Machine Learning · Computer Science 2020-06-16 Tianzhe Wang , Kuan Wang , Han Cai , Ji Lin , Zhijian Liu , Song Han

Structured pruning techniques have achieved great compression performance on convolutional neural networks for image classification task. However, the majority of existing methods are weight-oriented, and their pruning results may be…

Computer Vision and Pattern Recognition · Computer Science 2022-08-16 Yiheng Lu , Ziyu Guan , Yaming Yang , Maoguo Gong , Wei Zhao , Kaiyuan Feng