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Cross-lingual Cross-modal Retrieval (CCR) is an essential task in web search, which aims to break the barriers between modality and language simultaneously and achieves image-text retrieval in the multi-lingual scenario with a single model.…

Information Retrieval · Computer Science 2024-06-27 Zhijie Nie , Richong Zhang , Zhangchi Feng , Hailang Huang , Xudong Liu

While large language models (LLMs) have shown to perform well on monolingual mathematical and commonsense reasoning, they remain unreliable for multilingual medical reasoning applications, hindering their deployment in multilingual…

Artificial Intelligence · Computer Science 2026-04-28 Eric Onyame , Akash Ghosh , Subhadip Baidya , Sriparna Saha , Xiuying Chen , Chirag Agarwal

Contrastive learning (CL) has become a ubiquitous approach for several natural language processing (NLP) downstream tasks, especially for question answering (QA). However, the major challenge, how to efficiently train the knowledge…

Computation and Language · Computer Science 2022-03-31 Wenshen Xu , Mieradilijiang Maimaiti , Yuanhang Zheng , Xin Tang , Ji Zhang

Learning from electronic medical records (EMR) is challenging due to their relational nature and the uncertain dependence between a patient's past and future health status. Statistical relational learning is a natural fit for analyzing EMRs…

Machine Learning · Computer Science 2012-07-03 Jesse Davis , Vitor Santos Costa , Peggy Peissig , Michael Caldwell , Elizabeth Berg , David Page

Effectively integrating molecular graph structures with Large Language Models (LLMs) is a key challenge in drug discovery. Most existing multi-modal alignment methods typically process these structures by fine-tuning the LLM or adding a…

Machine Learning · Computer Science 2025-10-15 Tao Yin , Xiaohong Zhang , Jiacheng Zhang , Li Huang , Zhibin Zhang , Yuansong Zeng , Jin Xie , Meng Yan

Recent advancements in general-purpose or domain-specific multimodal large language models (LLMs) have witnessed remarkable progress for medical decision-making. However, they are designated for specific classification or generative tasks,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Songtao Jiang , Tuo Zheng , Yan Zhang , Yeying Jin , Li Yuan , Zuozhu Liu

Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle…

Computation and Language · Computer Science 2023-08-28 Chaoyi Wu , Weixiong Lin , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Objective: To optimize in-context learning in biomedical natural language processing by improving example selection. Methods: We introduce a novel multi-mode retrieval-augmented generation (MMRAG) framework, which integrates four retrieval…

Computation and Language · Computer Science 2025-02-25 Zaifu Zhan , Jun Wang , Shuang Zhou , Jiawen Deng , Rui Zhang

Medical vision-language models (VLMs) show strong performance on radiology tasks but often produce fluent yet weakly grounded conclusions due to over-reliance on a dominant modality. We introduce a context-aligned reasoning framework that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Sumra Khan , Sagar Chhabriya , Aizan Zafar , Sheeraz Arif , Amgad Muneer , Anas Zafar , Shaina Raza , Rizwan Qureshi

We present multilingual Pre-trained Machine Reader (mPMR), a novel method for multilingual machine reading comprehension (MRC)-style pre-training. mPMR aims to guide multilingual pre-trained language models (mPLMs) to perform natural…

Computation and Language · Computer Science 2023-05-24 Weiwen Xu , Xin Li , Wai Lam , Lidong Bing

Accurate and early diagnosis of malignant melanoma is critical for improving patient outcomes. While convolutional neural networks (CNNs) have shown promise in dermoscopic image analysis, they often neglect clinical metadata and require…

Computer Vision and Pattern Recognition · Computer Science 2025-09-11 Jihyun Moon , Charmgil Hong

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

In high-stakes medical applications, consistent answering across diverse question phrasings is essential for reliable diagnosis. However, we reveal that current Medical Vision-Language Models (Med-VLMs) exhibit concerning fragility in…

Computation and Language · Computer Science 2025-08-27 Songtao Jiang , Yuxi Chen , Sibo Song , Yan Zhang , Yeying Jin , Yang Feng , Jian Wu , Zuozhu Liu

Dynamic treatment recommendation systems based on large-scale electronic health records (EHRs) become a key to successfully improve practical clinical outcomes. Prior relevant studies recommend treatments either use supervised learning…

Machine Learning · Computer Science 2018-09-18 Lu Wang , Wei Zhang , Xiaofeng He , Hongyuan Zha

Recent Multimodal Large Language Models (MLLMs) have demonstrated significant progress in perceiving and reasoning over multimodal inquiries, ushering in a new research era for foundation models. However, vision-language misalignment in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Wei-Yao Wang , Zhao Wang , Helen Suzuki , Yoshiyuki Kobayashi

The utilization of Electronic Health Records (EHRs) for clinical risk prediction is on the rise. However, strict privacy regulations limit access to comprehensive health records, making it challenging to apply standard machine learning…

Computation and Language · Computer Science 2023-12-08 Angeela Acharya , Sulabh Shrestha , Anyi Chen , Joseph Conte , Sanja Avramovic , Siddhartha Sikdar , Antonios Anastasopoulos , Sanmay Das

Contemporary large language models (LLMs) may have utility for processing unstructured, narrative free-text clinical data contained in electronic health records (EHRs) -- a particularly important use-case for mental health where a majority…

Artificial Intelligence · Computer Science 2024-04-01 Niall Taylor , Andrey Kormilitzin , Isabelle Lorge , Alejo Nevado-Holgado , Dan W Joyce

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

Computation and Language · Computer Science 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Multimodal large language models (MLLMs) demonstrate considerable potential in clinical diagnostics, a domain that inherently requires synthesizing complex visual and textual data alongside consulting authoritative medical literature.…

Computation and Language · Computer Science 2026-03-23 Yannian Gu , Zhongzhen Huang , Linjie Mu , Xizhuo Zhang , Shaoting Zhang , Xiaofan Zhang
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