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The Segment Anything Model (SAM), a foundational model designed for promptable segmentation tasks, demonstrates exceptional generalization capabilities, making it highly promising for natural scene image segmentation. However, SAM's lack of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Linghao Zheng , Xinyang Pu , Feng Xu

The Segment Anything Model (SAM) has achieved remarkable successes in the realm of natural image segmentation, but its deployment in the medical imaging sphere has encountered challenges. Specifically, the model struggles with medical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Shreyank N Gowda , David A. Clifton

The success of large language models has inspired the computer vision community to explore image segmentation foundation model that is able to zero/few-shot generalize through prompt engineering. Segment-Anything(SAM), among others, is the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Haojie Zhang , Yongyi Su , Xun Xu , Kui Jia

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

The Segment Anything Model (SAM), a foundation model for general image segmentation, has demonstrated impressive zero-shot performance across numerous natural image segmentation tasks. However, SAM's performance significantly declines when…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Cheng Chen , Juzheng Miao , Dufan Wu , Zhiling Yan , Sekeun Kim , Jiang Hu , Aoxiao Zhong , Zhengliang Liu , Lichao Sun , Xiang Li , Tianming Liu , Pheng-Ann Heng , Quanzheng Li

Segment Anything Model (SAM) has received remarkable attention as it offers a powerful and versatile solution for object segmentation in images. However, fine-tuning SAM for downstream segmentation tasks under different scenarios remains a…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Zelin Peng , Zhengqin Xu , Zhilin Zeng , Xiaokang Yang , Wei Shen

Recent advancements in biomedical image analysis have been significantly driven by the Segment Anything Model (SAM). This transformative technology, originally developed for general-purpose computer vision, has found rapid application in…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Ho Hin Lee , Yu Gu , Theodore Zhao , Yanbo Xu , Jianwei Yang , Naoto Usuyama , Cliff Wong , Mu Wei , Bennett A. Landman , Yuankai Huo , Alberto Santamaria-Pang , Hoifung Poon

It has been shown that traditional deep learning methods for electronic microscopy segmentation usually suffer from low transferability when samples and annotations are limited, while large-scale vision foundation models are more robust…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Yiran Wang , Li Xiao

Due to the scarcity of annotated data and the substantial computational costs of model, conventional tuning methods in medical image segmentation face critical challenges. Current approaches to adapting pretrained models, including…

Computer Vision and Pattern Recognition · Computer Science 2025-12-05 Chenlin Xu , Lei Zhang , Lituan Wang , Xinyu Pu , Pengfei Ma , Guangwu Qian , Zizhou Wang , Yan Wang

Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Recent advancements in foundation models, such as the Segment Anything Model (SAM), have shown strong performance in various vision tasks, particularly image segmentation, due to their impressive zero-shot segmentation capabilities.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Pengfei Gu , Haoteng Tang , Islam A. Ebeid , Jose A. Nunez , Fabian Vazquez , Diego Adame , Marcus Zhan , Huimin Li , Bin Fu , Danny Z. Chen

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

The Segment Anything Model (SAM) represents a state-of-the-art research advancement in natural image segmentation, achieving impressive results with input prompts such as points and bounding boxes. However, our evaluation and recent…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Junlong Cheng , Jin Ye , Zhongying Deng , Jianpin Chen , Tianbin Li , Haoyu Wang , Yanzhou Su , Ziyan Huang , Jilong Chen , Lei Jiang , Hui Sun , Junjun He , Shaoting Zhang , Min Zhu , Yu Qiao

Semantic segmentation, a key task in computer vision with broad applications in autonomous driving, medical imaging, and robotics, has advanced substantially with deep learning. Nevertheless, current approaches remain vulnerable to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Iacopo Curti , Pierluigi Zama Ramirez , Alioscia Petrelli , Luigi Di Stefano

The Segment Anything Model (SAM) has recently demonstrated significant potential in medical image segmentation. Although SAM is primarily trained on 2D images, attempts have been made to apply it to 3D medical image segmentation. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Fangda Chen , Jintao Tang , Pancheng Wang , Ting Wang , Shasha Li , Ting Deng

In the last years, automated segmentation has become a necessary tool for volume electron microscopy (EM) imaging. So far, the best performing techniques have been largely based on fully supervised encoder-decoder CNNs, requiring a…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Joris Roels , Julian Hennies , Yvan Saeys , Wilfried Philips , Anna Kreshuk

The emergence of large models, also known as foundation models, has brought significant advancements to AI research. One such model is Segment Anything (SAM), which is designed for image segmentation tasks. However, as with other foundation…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Tianrun Chen , Lanyun Zhu , Chaotao Ding , Runlong Cao , Yan Wang , Zejian Li , Lingyun Sun , Papa Mao , Ying Zang

The Segment Anything Model (SAM) demonstrates impressive zero-shot segmentation ability on natural images but encounters difficulties in medical imaging due to domain shifts, anatomical variability, and its reliance on user-provided…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yingzhen Hu , Yiheng Zhong , Ruobing Li , Yingxue Su , Jiabao An , Feilong Tang , Jionglong Su , Imran Razzak

Medical Foundation Models (MFMs), trained on large-scale datasets, have demonstrated superior performance across various tasks. However, these models still struggle with domain gaps in practical applications. Specifically, even after…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Jia-Xuan Jiang , Wenhui Lei , Yifeng Wu , Hongtao Wu , Furong Li , Yining Xie , Xiaofan Zhang , Zhong Wang