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Animals learn to predict external contingencies from experience through a process of conditioning. A natural mechanism for conditioning is stimulus substitution, whereby the neuronal response to a stimulus with no prior behavioral…

Neurons and Cognition · Quantitative Biology 2024-09-23 Pantelis Vafidis , Antonio Rangel

The fields of artificial intelligence and neuroscience have a long history of fertile bi-directional interactions. On the one hand, important inspiration for the development of artificial intelligence systems has come from the study of…

Neurons and Cognition · Quantitative Biology 2019-11-21 Eilif B. Muller , Philippe Beaudoin

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Biological Physics · Physics 2017-05-09 Marat M. Rvachev

Artificial and natural neural network models are a new toolkit which could be potentially have been used for clarifying of complex brain functions. To attend this goal, such models need to be neurobiologically realistic. However, although…

Neurons and Cognition · Quantitative Biology 2022-07-08 Arsenii Onuchin

Connecting neural activity to function is a common aim in neuroscience. How to define and conceptualize function, however, can vary. Here I focus on grounding this goal in the specific question of how a given change in behavior is produced…

Neurons and Cognition · Quantitative Biology 2023-11-14 Grace W. Lindsay

Recent work in continual learning has highlighted the stability gap -- a temporary performance drop on previously learned tasks when new ones are introduced. This phenomenon reflects a mismatch between rapid adaptation and strong retention…

Machine Learning · Computer Science 2026-01-28 Alejandro Rodriguez-Garcia , Anindya Ghosh , Srikanth Ramaswamy

Learning underlies nearly all human behavior and is central to education and education reform. Although recent advances in neuroscience have revealed the fundamental structure of learning processes, these insights have yet to be integrated…

Information Theory · Computer Science 2025-10-20 Scott E. Allen , A. David Redish , René F. Kizilcec

The statelessness of foundation models bottlenecks agentic systems' ability to continually learn, a core capability for long-horizon reasoning and adaptation. To address this limitation, agentic systems commonly incorporate memory modules…

Artificial Intelligence · Computer Science 2026-02-10 Yiming Xiong , Shengran Hu , Jeff Clune

Dynamic adaptation in single-neuron response plays a fundamental role in neural coding in biological neural networks. Yet, most neural activation functions used in artificial networks are fixed and mostly considered as an inconsequential…

Machine Learning · Computer Science 2020-06-23 Victor Geadah , Giancarlo Kerg , Stefan Horoi , Guy Wolf , Guillaume Lajoie

A profound challenge for A-Life is to construct agents whose behavior is 'life-like' in a deep way. We propose an architecture and approach to constructing networks driving artificial agents, using processes analogous to the processes that…

Neural and Evolutionary Computing · Computer Science 2022-02-01 Addison Wood , Jory Schossau , Nick Sabaj , Richard Liu , Mark Reimers

Continual learning is a key feature of biological neural systems, but artificial neural networks often suffer from catastrophic forgetting. Instead of backpropagation, biologically plausible learning algorithms may enable stable continual…

Neural and Evolutionary Computing · Computer Science 2025-08-19 Denis Larionov , Nikolay Bazenkov , Mikhail Kiselev

The brain modifies its synaptic strengths during learning in order to better adapt to its environment. However, the underlying plasticity rules that govern learning are unknown. Many proposals have been suggested, including Hebbian…

Neurons and Cognition · Quantitative Biology 2020-12-09 Aran Nayebi , Sanjana Srivastava , Surya Ganguli , Daniel L. K. Yamins

Synaptic connections between neurons in the brain are dynamic because of continuously ongoing spine dynamics, axonal sprouting, and other processes. In fact, it was recently shown that the spontaneous synapse-autonomous component of spine…

Neurons and Cognition · Quantitative Biology 2018-01-08 David Kappel , Robert Legenstein , Stefan Habenschuss , Michael Hsieh , Wolfgang Maass

Neural Memory Networks (NMNs) have received increased attention in recent years compared to deep architectures that use a constrained memory. Despite their new appeal, the success of NMNs hinges on the ability of the gradient-based…

Computer Vision and Pattern Recognition · Computer Science 2020-11-12 Tharindu Fernando , Simon Denman , Sridha Sridharan , Clinton Fookes

It has been observed that neural networks perform poorly when the data or tasks are presented sequentially. Unlike humans, neural networks suffer greatly from catastrophic forgetting, making it impossible to perform life-long learning. To…

Machine Learning · Computer Science 2023-01-31 Longhui Yu , Tianyang Hu , Lanqing Hong , Zhen Liu , Adrian Weller , Weiyang Liu

Inspired by animal navigation strategies, we introduce a novel computational model to navigate and map a space rooted in biologically inspired principles. Animals exhibit extraordinary navigation prowess, harnessing memory, imagination, and…

Robotics · Computer Science 2025-01-07 Daria de Tinguy , Tim Verbelen , Bart Dhoedt

Sequential learning of multiple tasks in artificial neural networks using gradient descent leads to catastrophic forgetting, whereby previously learned knowledge is erased during learning of new, disjoint knowledge. Here, we propose a…

Machine Learning · Computer Science 2019-06-26 Shixian Wen , Laurent Itti

To cope with real-world dynamics, an intelligent system needs to incrementally acquire, update, accumulate, and exploit knowledge throughout its lifetime. This ability, known as continual learning, provides a foundation for AI systems to…

Machine Learning · Computer Science 2024-02-07 Liyuan Wang , Xingxing Zhang , Hang Su , Jun Zhu

Attempting to imitate the brain functionalities, researchers have bridged between neuroscience and artificial intelligence for decades; however, experimental neuroscience has not directly advanced the field of machine learning. Here, using…

Neurons and Cognition · Quantitative Biology 2020-05-11 Shira Sardi , Roni Vardi , Yuval Meir , Yael Tugendhaft , Shiri Hodassman , Amir Goldental , Ido Kanter

Recent work has shown that dopamine-modulated STDP can solve many of the issues associated with reinforcement learning, such as the distal reward problem. Spiking neural networks provide a useful technique in implementing reinforcement…

Neural and Evolutionary Computing · Computer Science 2015-02-24 Richard Evans