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Multimodal large language models (LLMs) are increasingly used to generate dermatology diagnostic narratives directly from images. However, reliable evaluation remains the primary bottleneck for responsible clinical deployment. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Yuhao Shen , Jiahe Qian , Shuping Zhang , Zhangtianyi Chen , Tao Lu , Juexiao Zhou

While large language models (LLMs) achieve near-perfect scores on medical licensing exams, these evaluations inadequately reflect the complexity and diversity of real-world clinical practice. We introduce MedHELM, an extensible evaluation…

Large Vision-Language Models (LVLMs) commonly follow a paradigm that projects visual features and then concatenates them with text tokens to form a unified sequence input for Large Language Models (LLMs). However, this paradigm leads to a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xinyu Wei , Guoli Yang , Jialu Zhou , Mingyue Yang , Leqian Li , Kedi Zhang , Chunping Qiu

Large language models (LLMs) are advancing at an unprecedented pace globally, with regions increasingly adopting these models for applications in their primary language. Evaluation of these models in diverse linguistic environments,…

Federated learning enables multiple medical institutions to train a global model without sharing data, yet feature heterogeneity from diverse scanners or protocols remains a major challenge. Many existing works attempt to address this issue…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Xingyue Zhao , Wenke Huang , Xingguang Wang , Haoyu Zhao , Linghao Zhuang , Anwen Jiang , Guancheng Wan , Mang Ye

Medical Large language models achieve strong scores on standard benchmarks; however, the transfer of those results to safe and reliable performance in clinical workflows remains a challenge. This survey reframes evaluation through a…

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Ensuring the general efficacy and goodness for human beings from medical large language models (LLM) before real-world deployment is crucial. However, a widely accepted and accessible evaluation process for medical LLM, especially in the…

Structured data offers a sophisticated mechanism for the organization of information. Existing methodologies for the text-serialization of structured data in the context of large language models fail to adequately address the heterogeneity…

Computation and Language · Computer Science 2024-02-20 YiQiu Guo , Yuchen Yang , Ya Zhang , Yu Wang , Yanfeng Wang

The development of robust clinical decision support systems is frequently impeded by the scarcity of high-fidelity, privacy-preserving biomedical data. While Generative Large Language Models (LLMs) offer a promising avenue for synthetic…

Machine Learning · Computer Science 2026-04-03 Arshia Ilaty , Hossein Shirazi , Amir Rahmani , Hajar Homayouni

Visual Question Answering in Medical domain (VQA-Med) plays an important role in providing medical assistance to the end-users. These users are expected to raise either a straightforward question with a Yes/No answer or a challenging…

Computation and Language · Computer Science 2020-09-29 Deepak Gupta , Swati Suman , Asif Ekbal

Many important classification problems in the real-world consist of a large number of closely related categories in a hierarchical structure or taxonomy. Hierarchical multi-label text classification (HMTC) with higher accuracy over large…

Computation and Language · Computer Science 2022-04-19 Pengfei Gao , Jingpeng Zhao , Yinglong Ma , Ahmad Tanvir , Beihong Jin

The acceleration of Large Language Models (LLMs) research has opened up new possibilities for evaluating generated texts. They serve as scalable and economical evaluators, but the question of how reliable these evaluators are has emerged as…

Computation and Language · Computer Science 2024-12-10 Minzhi Li , Zhengyuan Liu , Shumin Deng , Shafiq Joty , Nancy F. Chen , Min-Yen Kan

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Medical texts, particularly electronic medical records (EMRs), are a cornerstone of modern healthcare, capturing critical information about patient care, diagnoses, and treatments. These texts hold immense potential for advancing clinical…

Computation and Language · Computer Science 2025-11-12 Mucheng Ren , Yucheng Yan , He Chen , Danqing Hu , Jun Xu , Xian Zeng

Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Cheng Jin , Luyang Luo , Huangjing Lin , Jun Hou , Hao Chen

Cross-domain knowledge alignment is essential for integrating heterogeneous medical systems, yet existing approaches typically treat entity alignment as a static matching problem, ignoring query context and cross-system asymmetry. This…

Artificial Intelligence · Computer Science 2026-05-19 Yan Jiao , Jingran Xu , Pin-Han Ho , Limei Peng

The emergence of various medical large language models (LLMs) in the medical domain has highlighted the need for unified evaluation standards, as manual evaluation of LLMs proves to be time-consuming and labor-intensive. To address this…

Computation and Language · Computer Science 2023-12-21 Yan Cai , Linlin Wang , Ye Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

Accurate clinical coding is essential for healthcare documentation, billing, and decision-making. While prior work shows that off-the-shelf LLMs struggle with this task, evaluations based on exact match metrics often overlook errors where…

Computation and Language · Computer Science 2025-10-10 Zhangdie Yuan , Han-Chin Shing , Mitch Strong , Chaitanya Shivade
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