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Although the Segment Anything Model (SAM) is highly effective in natural image segmentation, it requires dependencies on prompts, which limits its applicability to medical imaging where manual prompts are often unavailable. Existing efforts…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Mengmeng Zhang , Xingyuan Dai , Yicheng Sun , Jing Wang , Yueyang Yao , Xiaoyan Gong , Fuze Cong , Feiyue Wang , Yisheng Lv

The recently introduced Segment Anything Model (SAM), a Visual Foundation Model (VFM), has demonstrated impressive capabilities in zero-shot segmentation tasks across diverse natural image datasets. Despite its success, SAM encounters…

Computer Vision and Pattern Recognition · Computer Science 2024-08-23 Chunpeng Zhou , Kangjie Ning , Qianqian Shen , Sheng Zhou , Zhi Yu , Haishuai Wang

Medical image segmentation involves partitioning medical images into meaningful regions, with a focus on identifying anatomical structures and lesions. It has broad applications in healthcare, and deep learning methods have enabled…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Donghang Lyu , Ruochen Gao , Marius Staring

The Segment Anything Model (SAM) exhibits promise in generic object segmentation and offers potential for various applications. Existing methods have applied SAM to surgical instrument segmentation (SIS) by tuning SAM-based frameworks with…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Wenxi Yue , Jing Zhang , Kun Hu , Qiuxia Wu , Zongyuan Ge , Yong Xia , Jiebo Luo , Zhiyong Wang

Medical images often exhibit distribution shifts due to variations in imaging protocols and scanners across different medical centers. Domain Generalization (DG) methods aim to train models on source domains that can generalize to unseen…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Yihang Fu , Ziyang Chen , Yiwen Ye , Xingliang Lei , Zhisong Wang , Yong Xia

The emerging scale segmentation model, Segment Anything (SAM), exhibits impressive capabilities in zero-shot segmentation for natural images. However, when applied to medical images, SAM suffers from noticeable performance drop. To make SAM…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Xinrong Hu , Xiaowei Xu , Yiyu Shi

Segment Anything Model (SAM) has gained significant recognition in the field of semantic segmentation due to its versatile capabilities and impressive performance. Despite its success, SAM faces two primary limitations: (1) it relies…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Yuchen Li , Li Zhang , Youwei Liang , Pengtao Xie

Recently, Segment Anything Model (SAM) has demonstrated strong generalizability in various instance segmentation tasks. However, its performance is severely dependent on the quality of manual prompts. In addition, the RGB images that…

Computer Vision and Pattern Recognition · Computer Science 2026-02-09 Yihan Shang , Wei Wang , Chao Huang , Xinghui Dong

The Segment Anything Model (SAM) has demonstrated impressive performance in zero-shot promptable segmentation on natural images. The recently released Segment Anything Model 2 (SAM 2) claims to outperform SAM on images and extends the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-16 Sourya Sengupta , Satrajit Chakrabarty , Ravi Soni

We propose a straightforward yet highly effective few-shot fine-tuning strategy for adapting the Segment Anything (SAM) to anatomical segmentation tasks in medical images. Our novel approach revolves around reformulating the mask decoder…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Shubham Patil , Yang Li , Mayank Kumar

The Segment Anything Model (SAM) can achieve satisfactory segmentation performance under high-quality box prompts. However, SAM's robustness is compromised by the decline in box quality, limiting its practicality in clinical reality. In…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Yuhao Huang , Xin Yang , Han Zhou , Yan Cao , Haoran Dou , Fajin Dong , Dong Ni

Segment anything model (SAM) demonstrates strong generalization ability on natural image segmentation. However, its direct adaptation in medical image segmentation tasks shows significant performance drops. It also requires an excessive…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Heng Guo , Jianfeng Zhang , Jiaxing Huang , Tony C. W. Mok , Dazhou Guo , Ke Yan , Le Lu , Dakai Jin , Minfeng Xu

With the proposal of the Segment Anything Model (SAM), fine-tuning SAM for medical image segmentation (MIS) has become popular. However, due to the large size of the SAM model and the significant domain gap between natural and medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jinfeng Wang , Sifan Song , Xinkun Wang , Yiyi Wang , Yiyi Miao , Jionglong Su , S. Kevin Zhou

The recently proposed Segment Anything Model (SAM) is a general tool for image segmentation, but it requires additional adaptation and careful fine-tuning for medical image segmentation, especially for small, irregularly-shaped, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Yaxi Chen , Aleksandra Ivanova , Shaheer U. Saeed , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu

Segmentation is a fundamental problem in surgical scene analysis using artificial intelligence. However, the inherent data scarcity in this domain makes it challenging to adapt traditional segmentation techniques for this task. To tackle…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Jay N. Paranjape , Nithin Gopalakrishnan Nair , Shameema Sikder , S. Swaroop Vedula , Vishal M. Patel

Large segmentation foundation models such as the Segment Anything Model (SAM) have reshaped promptable segmentation in natural images, and recent efforts have extended these models to medical images and volumetric settings. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Zixuan Tang , Shen Zhao

Foundational models such as the Segment Anything Model (SAM) are gaining traction in medical imaging segmentation, supporting multiple downstream tasks. However, such models are supervised in nature, still relying on large annotated…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Aishik Konwer , Zhijian Yang , Erhan Bas , Cao Xiao , Prateek Prasanna , Parminder Bhatia , Taha Kass-Hout

Large foundation models, known for their strong zero-shot generalization, have excelled in visual and language applications. However, applying them to medical image segmentation, a domain with diverse imaging types and target labels,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Junde Wu , Jiayuan Zhu , Yueming Jin , Min Xu

The Segment Anything Model (SAM) is a powerful foundation model that introduced revolutionary advancements in natural image segmentation. However, its performance remains sub-optimal when delineating the intricate structure of biomedical…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Xiangru Li , Yifei Zhang , Liang Zhao

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou