Related papers: O1 Replication Journey -- Part 3: Inference-time S…

Recent reasoning models, such as OpenAI's O1 series, have demonstrated exceptional performance on complex reasoning tasks and revealed new test-time scaling laws. Inspired by this, many people have been studying how to train models to…

Being prompted to engage in reasoning has emerged as a core technique for using large language models (LLMs), deploying additional inference-time compute to improve task performance. However, as LLMs increase in both size and adoption,…

Recent advancements in large language models (LLMs), such as DeepSeek-R1 and OpenAI-o1, have demonstrated the significant effectiveness of test-time scaling, achieving substantial performance gains across various benchmarks. These advanced…

Large language models (LLMs) are entering clinician workflows, yet evaluations rarely measure how clinician reasoning shapes model behavior during clinical interactions. We combined 61 New England Journal of Medicine Case Records with 92…

Large Language Models (LLMs) are revolutionizing medical diagnostics by enhancing both disease classification and clinical decision-making. In this study, we evaluate the performance of two LLM- based diagnostic tools, DeepSeek R1 and O3…

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Recent trends in test-time scaling for reasoning models (e.g., OpenAI o1, DeepSeek R1) have led to a popular belief that extending thinking traces using prompts like "Wait" or "Let me rethink" can improve performance. This raises a natural…

Despite rapid advancements in large language models (LLMs), the token-level autoregressive nature constrains their complex reasoning capabilities. To enhance LLM reasoning, inference-time techniques, including…

Progress on training and architecture strategies has enabled LLMs with millions of tokens in context length. However, empirical evidence suggests that such long-context LLMs can consume far more text than they can reliably use. On the other…

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

While the scaling laws of large language models (LLMs) training have been extensively studied, optimal inference configurations of LLMs remain underexplored. We study inference scaling laws (aka test-time scaling laws) and compute-optimal…

Generative retrieval reformulates retrieval as an autoregressive generation task, where large language models (LLMs) generate target documents directly from a query. As a novel paradigm, the mechanisms that underpin its performance and…

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

There is intense interest in investigating how inference time compute (ITC) (e.g. repeated sampling, refinements, etc) can improve large language model (LLM) capabilities. At the same time, recent breakthroughs in reasoning models, such as…

Large Language Models (LLMs), particularly smaller variants, still struggle with complex reasoning tasks. While inference-time prompting can guide reasoning, existing methods often rely on sequential queries. Ensemble approaches offer a…

Large language models (LLMs) are capable of many natural language tasks, yet they are far from perfect. In health applications, grounding and interpreting domain-specific and non-linguistic data is crucial. This paper investigates the…

Large language models (LLMs) can improve reasoning at inference time through test-time scaling (TTS), where multiple reasoning traces are generated and the best one is selected. Prior work shows that increasing the number of samples K…

Recent research has highlighted that Large Language Models (LLMs), even when trained to generate extended long reasoning steps, still face significant challenges on hard reasoning problems. However, much of the existing literature relies on…

Large language models (LLMs) are increasingly explored for clinical decision support, yet most evaluations are conducted in English, leaving their reliability in other languages uncertain. Here we evaluate the impact of prompting language…

Large language models (LLMs) have demonstrated impressive reasoning capabilities by scaling test-time compute via long Chain-of-Thought (CoT). However, recent findings suggest that raw token counts are unreliable proxies for reasoning…