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User specifications or legal frameworks often require information to be removed from pretrained models, including large language models (LLMs). This requires deleting or "forgetting" a set of data points from an already-trained model, which…

Machine Learning · Computer Science 2025-07-18 Vaidehi Patil , Elias Stengel-Eskin , Mohit Bansal

Deep Learning (DL) is increasingly used in safety-critical applications, raising concerns about its reliability. DL suffers from a well-known problem of lacking robustness, especially when faced with adversarial perturbations known as…

Software Engineering · Computer Science 2023-09-06 Wei Huang , Xingyu Zhao , Alec Banks , Victoria Cox , Xiaowei Huang

Many attempts have been done to extend the great success of convolutional neural networks (CNNs) achieved on high-end GPU servers to portable devices such as smart phones. Providing compression and acceleration service of deep learning…

Machine Learning · Computer Science 2019-10-09 Yixing Xu , Yunhe Wang , Hanting Chen , Kai Han , Chunjing Xu , Dacheng Tao , Chang Xu

While deep learning methods hitherto have achieved considerable success in medical image segmentation, they are still hampered by two limitations: (i) reliance on large-scale well-labeled datasets, which are difficult to curate due to the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Ziyuan Zhao , Fangcheng Zhou , Kaixin Xu , Zeng Zeng , Cuntai Guan , S. Kevin Zhou

Deep neural networks have achieved outstanding performance over various tasks, but they have a critical issue: over-confident predictions even for completely unknown samples. Many studies have been proposed to successfully filter out these…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Jihyo Kim , Jiin Koo , Sangheum Hwang

Recent studies have demonstrated the effectiveness of clustering-based approaches for self-supervised and unsupervised learning. However, the application of clustering is often heuristic, and the optimal methodology remains unclear. In this…

Machine Learning · Computer Science 2025-11-10 Xiaodong Wang , Jing Huang , Kevin J Liang

Learning a medical image segmentation model is an inherently ambiguous task, as uncertainties exist in both images (noise) and manual annotations (human errors and bias) used for model training. To build a trustworthy image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Xinyu Bai , Wenjia Bai

Clustering, as an unsupervised technique, plays a pivotal role in various data analysis applications. Among clustering algorithms, Spectral Clustering on Euclidean Spaces has been extensively studied. However, with the rapid evolution of…

Machine Learning · Computer Science 2024-12-09 Sagar Ghosh , Swagatam Das

Background: The huge quantity of data produced in Biomedical research needs sophisticated algorithmic methodologies for its storage, analysis, and processing. High Performance Computing (HPC) appears as a magic bullet in this challenge.…

Quantitative Methods · Quantitative Biology 2016-10-19 Gianni D'Angelo , Salvatore Rampone

Deep Learning methods are known to suffer from calibration issues: they typically produce over-confident estimates. These problems are exacerbated in the low data regime. Although the calibration of probabilistic models is well studied,…

Machine Learning · Statistics 2021-11-30 Rahul Rahaman , Alexandre H. Thiery

The modern deep learning field is a scale-centric one. Larger models have been shown to consistently perform better than smaller models of similar architecture. In many sub-domains of biomedical research, however, the model scaling is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Nicholas Kuang , Vanessa Scalon , Ji Yu

Improving calibration performance in deep learning (DL) classification models is important when planning the use of DL in a decision-support setting. In such a scenario, a confident wrong prediction could lead to a lack of trust and/or harm…

Machine Learning · Computer Science 2024-05-13 Tareen Dawood , Bram Ruijsink , Reza Razavi , Andrew P. King , Esther Puyol-Antón

This work demonstrates the ability to produce readily interpretable statistical metrics for model fit, fixed effects covariance coefficients, and prediction confidence. Importantly, this work compares 4 suitable and commonly applied…

Machine Learning · Statistics 2022-11-30 Alex Treacher , Kevin Nguyen , Dylan Owens , Daniel Heitjan , Albert Montillo

The focus of this study is on Unsupervised Continual Learning (UCL), as it presents an alternative to Supervised Continual Learning which needs high-quality manual labeled data. The experiments under the UCL paradigm indicate a phenomenon…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Chen Cheng , Jingkuan Song , Xiaosu Zhu , Junchen Zhu , Lianli Gao , Hengtao Shen

Stanford Medicine is building a new data platform for our academic research community to do better clinical data science. Hospitals have a large amount of patient data and researchers have demonstrated the ability to reuse that data and AI…

With evolving data regulations, machine unlearning (MU) has become an important tool for fostering trust and safety in today's AI models. However, existing MU methods focusing on data and/or weight perspectives often suffer limitations in…

Machine Learning · Computer Science 2024-04-05 Chongyu Fan , Jiancheng Liu , Yihua Zhang , Eric Wong , Dennis Wei , Sijia Liu

Medical image analysis using supervised deep learning methods remains problematic because of the reliance of deep learning methods on large amounts of labelled training data. Although medical imaging data repositories continue to expand…

Computer Vision and Pattern Recognition · Computer Science 2019-06-11 Euijoon Ahn , Ashnil Kumar , Dagan Feng , Michael Fulham , Jinman Kim

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

Artificial Intelligence (AI) has demonstrated significant potential in automating various medical imaging tasks, which could soon become routine in clinical practice for disease diagnosis, prognosis, treatment planning, and post-treatment…

Image and Video Processing · Electrical Eng. & Systems 2024-09-26 Nikolas Koutsoubis , Asim Waqas , Yasin Yilmaz , Ravi P. Ramachandran , Matthew Schabath , Ghulam Rasool