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Many clinical deep learning algorithms are population-based and difficult to interpret. Such properties limit their clinical utility as population-based findings may not generalize to individual patients and physicians are reluctant to…

Signal Processing · Electrical Eng. & Systems 2020-12-01 Dani Kiyasseh , Tingting Zhu , David A. Clifton

Reliable identification of molecular biomarkers is essential for accurate patient stratification. While state-of-the-art machine learning approaches for sample classification continue to push boundaries in terms of performance, most of…

Molecular Networks · Quantitative Biology 2019-11-07 Matteo Manica , Joris Cadow , Roland Mathis , María Rodríguez Martínez

Histopathology is essential for disease diagnosis and treatment decision-making. Recent advances in artificial intelligence (AI) have enabled the development of pathology foundation models that learn rich visual representations from…

Despite their ubiquity, the rich physics present in a plasma sheath has inhibited the development of a generally applicable description of this critical region. The present study utilizes a physics-informed neural network (PINN) to evaluate…

Plasma Physics · Physics 2026-04-27 Ethan Webb , Yuzhi Li , Christopher McDevitt

Model-agnostic explanation methods for deep learning models are flexible regarding usability and availability. However, due to the fact that they can only manipulate input to see changes in output, they suffer from weak performance when…

Computer Vision and Pattern Recognition · Computer Science 2024-02-05 Maurice Günder , Sneha Banerjee , Rafet Sifa , Christian Bauckhage

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

Machine Learning · Computer Science 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

The rapid digitization of histopathology slides has opened up new possibilities for computational tools in clinical and research workflows. Among these, content-based slide retrieval stands out, enabling pathologists to identify…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hongyi Wang , Zhengjie Zhu , Jiabo Ma , Fang Wang , Yue Shi , Bo Luo , Jili Wang , Qiuyu Cai , Xiuming Zhang , Yen-Wei Chen , Lanfen Lin , Hao Chen

Finding interpretable biomechanical models can provide insight into the functionality of organs with regard to physiology and disease. However, identifying broadly applicable dynamical models for in vivo tissue remains challenging. In this…

Model discovery aims at autonomously discovering differential equations underlying a dataset. Approaches based on Physics Informed Neural Networks (PINNs) have shown great promise, but a fully-differentiable model which explicitly learns…

Machine Learning · Statistics 2021-10-06 Gert-Jan Both , Remy Kusters

The field of computational pathology has witnessed great advancements since deep neural networks have been widely applied. These networks usually require large numbers of annotated data to train vast parameters. However, it takes…

Computer Vision and Pattern Recognition · Computer Science 2022-08-11 Yixiao Zhang , Adam Kortylewski , Qing Liu , Seyoun Park , Benjamin Green , Elizabeth Engle , Guillermo Almodovar , Ryan Walk , Sigfredo Soto-Diaz , Janis Taube , Alex Szalay , Alan Yuille

Representation learning is a critical ingredient for natural language processing systems. Recent Transformer language models like BERT learn powerful textual representations, but these models are targeted towards token- and sentence-level…

Computation and Language · Computer Science 2020-05-21 Arman Cohan , Sergey Feldman , Iz Beltagy , Doug Downey , Daniel S. Weld

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

The complexity and variability inherent in high-resolution pathological images present significant challenges in computational pathology. While pathology foundation models leveraging AI have catalyzed transformative advancements, their…

Path planning is an important topic in robotics. Recently, value iteration based deep learning models have achieved good performance such as Value Iteration Network(VIN). However, previous methods suffer from slow convergence and low…

Robotics · Computer Science 2021-04-30 Buqing Nie , Yue Gao , Yidong Mei , Feng Gao

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Zhe Li , Bernhard Kainz

Retrieving code functions, classes or files that are relevant in order to solve a given user query, bug report or feature request from large codebases is a fundamental challenge for Large Language Model (LLM)-based coding agents. Agentic…

Software Engineering · Computer Science 2026-02-09 Shravan Chaudhari , Rahul Thomas Jacob , Mononito Goswami , Jiajun Cao , Shihab Rashid , Christian Bock

This paper presents a novel method for discovering systematic errors in segmentation models. For instance, a systematic error in the segmentation model can be a sufficiently large number of misclassifications from the model as a parking…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Jaisidh Singh , Sonam Singh , Amit Arvind Kale , Harsh K Gandhi

Robust inference for stochastic dynamical systems is often hampered by sparse sampling and the absence of closed-form likelihoods. We introduce a Monte Carlo path-inference framework that leverages full-path statistics and bridge processes…

Statistical Mechanics · Physics 2025-10-07 Javier Aguilar , Miguel A. Muñoz , Sandro Azaele

Differentiable causal discovery has made significant advancements in the learning of directed acyclic graphs. However, its application to real-world datasets remains restricted due to the ubiquity of latent confounders and the requirement…

Machine Learning · Computer Science 2024-06-18 Pingchuan Ma , Rui Ding , Qiang Fu , Jiaru Zhang , Shuai Wang , Shi Han , Dongmei Zhang