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In the present paper we analyze the linear stability of a hierarchical size-structured population model where the vital rates (mortality, fertility and growth rate) depend both on size and a general functional of the population density…

Analysis of PDEs · Mathematics 2019-03-25 Jozsef Z. Farkas , Thomas C. Hagen

While the use of spatial agent-based and individual-based models has flourished across many scientific disciplines, the complexities these models generate are often difficult to manage and quantify. This research reduces population-driven,…

Physics and Society · Physics 2021-08-24 John C. Stevenson

Single-cell experiments have revealed cell-to-cell variability in generation times and growth rates for genetically identical cells. Theoretical models relating the fluctuating generation times of single cells to the population growth rate…

Populations and Evolution · Quantitative Biology 2020-01-15 Jie Lin , Ariel Amir

Will the United Kingdom's ageing population be fit and independent, or suffer from greater chronic ill health? Healthy life expectancy is commonly used to assess this: it is an estimate of how many years are lived in good health over the…

Statistics Theory · Mathematics 2007-06-13 Ehsan Khoman , Martin Weale

A tumor can be thought of as an ecosystem, which critically means that we cannot just consider it as a collection of mutated cells but more as a complex system of many interacting cellular and microenvironmental elements. At its simplest, a…

Populations and Evolution · Quantitative Biology 2013-05-03 Jill Gallaher , Alexander R. A. Anderson

We consider populations structured by a phenotypic trait and a space variable, in a non-homogeneous environment. In the case of sex- ual populations, we are able to derive models close to existing mod- els in theoretical biology, from a…

Analysis of PDEs · Mathematics 2011-05-11 Sepideh Mirrahimi , Gael Raoul

Aging is thought to be a consequence of intrinsic breakdowns in how genetic information is processed. But mounting experimental evidence suggests that aging can be slowed. To help resolve this mystery, I derive a mortality equation which…

Populations and Evolution · Quantitative Biology 2022-09-01 Thomas Fink

Coalescent theory combined with statistical modeling allows us to estimate effective population size fluctuations from molecular sequences of individuals sampled from a population of interest. When sequences are sampled serially through…

Populations and Evolution · Quantitative Biology 2021-11-02 Michael D. Karcher , Marc A. Suchard , Gytis Dudas , Vladimir N. Minin

Heterogeneous systems of active matter exhibit a range of complex emergent dynamical patterns. In particular, it is difficult to predict the properties of the mixed system based on its constituents. These considerations are particularly…

Soft Condensed Matter · Physics 2021-04-07 Shlomit Peled , Shawn D. Ryan , Sebastian Heidenreich , Markus Bar , Gil Ariel , Avraham Be'er

The paper explores the influence of harvesting (or culling) on the outcome of the competition of two species in a spatially heterogeneous environment. The harvesting effort is assumed to be proportional to the space-dependent intrinsic…

Dynamical Systems · Mathematics 2019-05-01 Elena Braverman , Ilia Ilmer

We consider a model of asexually reproducing individuals. The birth and death rates of the individuals are affected by a fitness parameter. The rate of mutations that cause the fitnesses to change is proportional to the population size, N.…

Probability · Mathematics 2013-07-24 Michael Kelly

Heterogeneity of population is a key factor in modeling the transmission of disease among the population and has huge impact on the outcome of the transmission. In order to investigate the decision making process in the heterogeneous mixing…

Populations and Evolution · Quantitative Biology 2024-03-01 Fan Bai , Qianyu Chen , Yizhuo Xu

Recent empirical observations suggest a heterogeneous nature of human activities. The heavy-tailed inter-event time distribution at population level is well accepted, while whether the individual acts in a heterogeneous way is still under…

Data Analysis, Statistics and Probability · Physics 2015-05-28 Zimo Yang , Ai-Xiang Cui , Tao Zhou

Heterogeneity in physical and functional characteristics of cells (e.g. size, cycle time, growth rate, protein concentration) proliferates within an isogenic population due to stochasticity in intracellular biochemical processes and in the…

Cell Behavior · Quantitative Biology 2021-02-02 Harsh Vashistha , Maryam Kohram , Hanna Salman

This paper studies fitness inheritance as an efficiency enhancement technique for a class of competent genetic algorithms called estimation distribution algorithms. Probabilistic models of important sub-solutions are developed to estimate…

Neural and Evolutionary Computing · Computer Science 2016-11-17 Kumara Sastry , Martin Pelikan , David E. Goldberg

In large asexual populations, multiple beneficial mutations arise in the population, compete, interfere with each other, and accumulate on the same genome, before any of them fix. The resulting dynamics, although studied by many authors, is…

Populations and Evolution · Quantitative Biology 2015-06-11 Daniel S. Fisher

The population size has far-reaching effects on the fitness of the population, that, in its turn influences the population extinction or persistence. Understanding the density- and age-dependent factors will facilitate more accurate…

Dynamical Systems · Mathematics 2021-02-12 Jonathan Andersson , Vladimir Kozlov , Vladimir G. Tkachev , Sonja Radosavljevic , Uno Wennergren

Evolutionary games on networks traditionally involve the same game at each interaction. Here we depart from this assumption by considering mixed games, where the game played at each interaction is drawn uniformly at random from a set of two…

Physics and Society · Physics 2016-05-23 Marco A. Amaral , Lucas Wardil , Matjaz Perc , Jafferson K. L. da Silva

When a collection of phenotypically diverse organisms compete with each other for limited resources, with competition being strongest amongst the most similar, the population can evolve into tightly localised clusters. This process can be…

Populations and Evolution · Quantitative Biology 2012-05-16 Tim Rogers , Alan J. McKane , Axel G. Rossberg

Many single-cell observables are highly heterogeneous. A part of this heterogeneity stems from age-related phenomena: the fact that there is a nonuniform distribution of cells with different ages. This has led to a renewed interest in…

Quantitative Methods · Quantitative Biology 2018-04-18 Nash Rochman , Dan Popescu , Sean X. Sun