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Foundation models (FMs), large neural networks pretrained on extensive and diverse datasets, have revolutionized artificial intelligence and shown significant promise in medical imaging by enabling robust performance with limited labeled…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Salah Ghamizi , Georgia Kanli , Yu Deng , Magali Perquin , Olivier Keunen

Brain morphology is shaped by genetic and mechanical factors and is linked to biological development and diseases. Its fractal-like features, regional anisotropy, and complex curvature distributions hinder quantitative insights in medical…

Neurons and Cognition · Quantitative Biology 2025-09-09 Yingjie Zhao , Yicheng Song , Fan Xu , Zhiping Xu

Early brain development is characterized by the formation of a highly organized structural connectome. The interconnected nature of this connectome underlies the brain's cognitive abilities and influences its response to diseases and…

Neurons and Cognition · Quantitative Biology 2023-08-24 Yihan Wu , Lana Vasung , Camilo Calixto , Ali Gholipour , Davood Karimi

Multimodal neuroimaging grants a powerful in vivo window into the structure and function of the human brain. Recent methodological and conceptual advances have enabled investigations of the interplay between large-scale spatial trends, or…

Background: Information processing in the brain requires large amounts of metabolic energy, the spatial distribution of which is highly heterogeneous reflecting complex activity patterns in the mammalian brain. Results: Here, it is found…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jan Karbowski

The modern deep learning field is a scale-centric one. Larger models have been shown to consistently perform better than smaller models of similar architecture. In many sub-domains of biomedical research, however, the model scaling is…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Nicholas Kuang , Vanessa Scalon , Ji Yu

Whole brain neuroanatomy using tera-voxel light-microscopic data sets is of much current interest. A fundamental problem in this field is the mapping of individual brain data sets to a reference space. Previous work has not rigorously…

Neurons and Cognition · Quantitative Biology 2019-04-18 Brian C. Lee , Meng Kuan Lin , Yan Fu , Junichi Hata , Michael I. Miller , Partha P. Mitra

Image Quality of MRI brain scans is strongly influenced by within scanner head movements and the resulting image artifacts alter derived measures like brain volume and cortical thickness. Automated image quality assessment is key to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Felix Hoffstaedter , Nicolás Nieto , Simon B. Eickhoff , Kaustubh R. Patil

The human brain exhibits a complex structure made of scale-free highly connected modules loosely interconnected by weaker links to form a small-world network. These features appear in healthy patients whereas neurological diseases often…

Neurons and Cognition · Quantitative Biology 2014-03-26 Roberta Russo , Hans J Herrmann , Lucilla de Arcangelis

Accurate fetal brain tissue segmentation and biometric analysis are essential for studying brain development in utero. The FeTA Challenge 2024 advanced automated fetal brain MRI analysis by introducing biometry prediction as a new task…

Cortical thickness measurements from magnetic resonance imaging, an important biomarker in many neurodegenerative and neurological disorders, are derived by many tools from an initial voxel-wise tissue segmentation. White matter (WM)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-27 Vinzenz Uhr , Ivan Diaz , Christian Rummel , Richard McKinley

Motivated by problems from neuroimaging in which existing approaches make use of "mass univariate" analysis which neglects spatial structure entirely, but the full joint modelling of all quantities of interest is computationally infeasible,…

Methodology · Statistics 2022-04-19 Denishrouf Thesingarajah , Adam M. Johansen

The properties of tissue interfaces -- between separate populations of cells, or between a group of cells and its environment -- has attracted intense theoretical, computational, and experimental study. Recent work on shape-based models…

Soft Condensed Matter · Physics 2024-12-04 Haicen Yue , Charles R. Packard , Daniel M. Sussman

In a follow-up study to a previous analysis of the IRAS 1.2Jy catalogue, we quantify the morphological fluctuations in the PSCz survey. We use a variety of measures, among them the family of scalar Minkowski functionals. We confirm the…

Astrophysics · Physics 2009-08-07 M. Kerscher , K. Mecke , J. Schmalzing , C. Beisbart , T. Buchert , H. Wagner

Alignment between non-rigid stretchable structures is one of the most challenging tasks in computer vision, as the invariant properties are hard to define, and there is no labeled data for real datasets. We present unsupervised neural…

Computer Vision and Pattern Recognition · Computer Science 2022-08-30 Idan Pazi , Dvir Ginzburg , Dan Raviv

The correct reconstruction of individual (crossing) nerve fibers is a prerequisite when constructing a detailed network model of the brain. The recently developed technique Scattered Light Imaging (SLI) allows the reconstruction of crossing…

Biological Physics · Physics 2021-11-30 Miriam Menzel , Marouan Ritzkowski , Jan André Reuter , David Gräßel , Katrin Amunts , Markus Axer

Non-rigid cortical registration is an important and challenging task due to the geometric complexity of the human cortex and the high degree of inter-subject variability. A conventional solution is to use a spherical representation of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Jieyu Cheng , Adrian V. Dalca , Bruce Fischl , Lilla Zollei

Current AI frameworks for brain decoding and encoding, typically train and test models within the same datasets. This limits their utility for brain computer interfaces (BCI) or neurofeedback, for which it would be useful to pool…

Living biological tissue is a complex system, constantly growing and changing in response to external and internal stimuli. These processes lead to remarkable and intricate changes in shape. Modeling and understanding both natural and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Edwin Tay , Nazli Tümer , Amir A. Zadpoor

It is of great interest to quantify the contributions of genetic variation to brain structure and function, which are usually measured by high-dimensional imaging data (e.g., magnetic resonance imaging). In addition to the variance, the…

Applications · Statistics 2020-05-05 Benjamin B. Risk , Hongtu Zhu