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Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

The field of computational pathology has witnessed great advancements since deep neural networks have been widely applied. These networks usually require large numbers of annotated data to train vast parameters. However, it takes…

Computer Vision and Pattern Recognition · Computer Science 2022-08-11 Yixiao Zhang , Adam Kortylewski , Qing Liu , Seyoun Park , Benjamin Green , Elizabeth Engle , Guillermo Almodovar , Ryan Walk , Sigfredo Soto-Diaz , Janis Taube , Alex Szalay , Alan Yuille

Accurate segmentation of lesions plays a critical role in medical image analysis and diagnosis. Traditional segmentation approaches that rely solely on visual features often struggle with the inherent uncertainty in lesion distribution and…

Image and Video Processing · Electrical Eng. & Systems 2025-04-03 Dandan Shan , Zihan Li , Yunxiang Li , Qingde Li , Jie Tian , Qingqi Hong

Recently, the state-of-art models for medical image segmentation is U-Net and their variants. These networks, though succeeding in deriving notable results, ignore the practical problem hanging over the medical segmentation field:…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Hao Ziang , Jingsi Zhang , Lixian Li

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

Due to the lack of quality annotation in medical imaging community, semi-supervised learning methods are highly valued in image semantic segmentation tasks. In this paper, an advanced consistency-aware pseudo-label-based self-ensembling…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Ziyang Wang , Tianze Li , Jian-Qing Zheng , Baoru Huang

Despite their outstanding accuracy, semi-supervised segmentation methods based on deep neural networks can still yield predictions that are considered anatomically impossible by clinicians, for instance, containing holes or disconnected…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Ping Wang , Jizong Peng , Marco Pedersoli , Yuanfeng Zhou , Caiming Zhang , Christian Desrosiers

This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…

Current methods for developing foundation models in medical image segmentation rely on two primary assumptions: a fixed set of classes and the immediate availability of a substantial and diverse training dataset. However, this can be…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Xiaoyang Chen , Hao Zheng , Yifang Xie , Yuncong Ma , Tengfei Li

Semi-supervised learning (SSL) has become a promising solution to alleviate the annotation burden of deep learning-based medical image segmentation models. While recent advances in foundation model-driven SSL have pushed the boundary to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yichi Zhang , Le Xue , Bichun Xu , Judong Luo , Zhigang Wu , Yu Fu , Zixin Hu , Yuan Cheng , Yuan Qi

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Sishuo Liu , Yizhou Yu , Guanbin Li

Identifying cell types and subtypes in routine histopathology is fundamental for understanding disease. Existing tile-based models capture nuclear detail but miss the broader tissue context that influences cell identity. Current human…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Yinuo Xu , Yan Cui , Mingyao Li , Zhi Huang

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

Quantitative Methods · Quantitative Biology 2025-08-26 Surajit Das , Gourav Roy , Pavel Zun

Medical image segmentation plays an essential role in developing computer-assisted diagnosis and therapy systems, yet still faces many challenges. In the past few years, the popular encoder-decoder architectures based on CNNs (e.g., U-Net)…

Computer Vision and Pattern Recognition · Computer Science 2021-07-20 Guoping Xu , Xingrong Wu , Xuan Zhang , Xinwei He

In clinical practice, medical image analysis often requires efficient execution on resource-constrained mobile devices. However, existing mobile models-primarily optimized for natural images-tend to perform poorly on medical tasks due to…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Fenghe Tang , Bingkun Nian , Jianrui Ding , Wenxin Ma , Quan Quan , Chengqi Dong , Jie Yang , Wei Liu , S. Kevin Zhou

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast…

Computer Vision and Pattern Recognition · Computer Science 2020-02-21 Pierre Courtiol , Eric W. Tramel , Marc Sanselme , Gilles Wainrib

Purpose: Accurate segmentation of lung and infection in COVID-19 CT scans plays an important role in the quantitative management of patients. Most of the existing studies are based on large and private annotated datasets that are…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Jun Ma , Yixin Wang , Xingle An , Cheng Ge , Ziqi Yu , Jianan Chen , Qiongjie Zhu , Guoqiang Dong , Jian He , Zhiqiang He , Yuntao Zhu , Ziwei Nie , Xiaoping Yang

Medical image segmentation plays a crucial role in various healthcare applications, enabling accurate diagnosis, treatment planning, and disease monitoring. Traditionally, convolutional neural networks (CNNs) dominated this domain,…

Semantic Segmentation is one of the most challenging vision tasks, usually requiring large amounts of training data with expensive pixel level annotations. With the success of foundation models and especially vision-language models, recent…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Soroush Seifi , Daniel Olmeda Reino , Fabien Despinoy , Rahaf Aljundi