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In recent years, there has been substantial progress in using pretrained Language Models (LMs) on a range of tasks aimed at improving the understanding of biomedical texts. Nonetheless, existing biomedical LLMs show limited comprehension of…

Computation and Language · Computer Science 2025-09-10 Andrey Sakhovskiy , Elena Tutubalina

Considering the limited internal parametric knowledge, retrieval-augmented generation (RAG) has been widely used to extend the knowledge scope of large language models (LLMs). Despite the extensive efforts on RAG research, in existing…

Computation and Language · Computer Science 2024-11-22 Yuhao Wang , Ruiyang Ren , Junyi Li , Wayne Xin Zhao , Jing Liu , Ji-Rong Wen

Accurate recognition of biomedical named entities is critical for medical information extraction and knowledge discovery. However, existing methods often struggle with nested entities, entity boundary ambiguity, and cross-lingual…

Computation and Language · Computer Science 2025-10-13 Tengxiao Lv , Ling Luo , Juntao Li , Yanhua Wang , Yuchen Pan , Chao Liu , Yanan Wang , Yan Jiang , Huiyi Lv , Yuanyuan Sun , Jian Wang , Hongfei Lin

Extracting information from full documents is an important problem in many domains, but most previous work focus on identifying relationships within a sentence or a paragraph. It is challenging to create a large-scale information extraction…

Computation and Language · Computer Science 2020-05-04 Sarthak Jain , Madeleine van Zuylen , Hannaneh Hajishirzi , Iz Beltagy

Multi-modal Retrieval-Augmented Generation (RAG) has become a critical method for empowering LLMs by leveraging candidate visual documents. However, current methods consider the entire document as the basic retrieval unit, introducing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Yinglu Li , Zhiying Lu , Zhihang Liu , Yiwei Sun , Chuanbin Liu , Hongtao Xie

In this paper, we investigate how semantic relations between concepts extracted from medical documents can be employed to improve the retrieval of medical literature. Semantic relations explicitly represent relatedness between concepts and…

Information Retrieval · Computer Science 2019-05-06 Maristella Agosti , Giorgio Maria Di Nunzio , Stefano Marchesin , Gianmaria Silvello

Retrieval-Augmented Generation (RAG) is a powerful technique for enriching Large Language Models (LLMs) with external knowledge, allowing for factually grounded responses, a critical requirement in high-stakes domains such as healthcare.…

Computation and Language · Computer Science 2025-10-07 Eduardo Martínez Rivera , Filippo Menolascina

As an effective method to boost the performance of Large Language Models (LLMs) on the question answering (QA) task, Retrieval-Augmented Generation (RAG), which queries highly relevant information from external complex documents, has…

Information Retrieval · Computer Science 2025-12-04 Shu Wang , Yingli Zhou , Yixiang Fang

Document-level relation extraction aims to discover relations between entities across a whole document. How to build the dependency of entities from different sentences in a document remains to be a great challenge. Current approaches…

Computation and Language · Computer Science 2021-03-16 Jiaxin Pan , Min Peng , Yiyan Zhang

Relation extraction (RE) is a standard information extraction task playing a major role in downstream applications such as knowledge discovery and question answering. Although decoder-only large language models are excelling in generative…

Computation and Language · Computer Science 2025-07-28 Yuhang Jiang , Ramakanth Kavuluru

Biomedical entity linking and event extraction are two crucial tasks to support text understanding and retrieval in the biomedical domain. These two tasks intrinsically benefit each other: entity linking disambiguates the biomedical…

Computation and Language · Computer Science 2023-05-25 Xiaochu Li , Minqian Liu , Zhiyang Xu , Lifu Huang

Current general-purpose large language models (LLMs) commonly exhibit knowledge hallucination and insufficient domain-specific adaptability in domain-specific tasks, limiting their effectiveness in specialized question answering scenarios.…

Information Retrieval · Computer Science 2025-09-16 Mengzheng Yang , Yanfei Ren , David Osei Opoku , Ruochang Li , Peng Ren , Chunxiao Xing

Relation extraction is the task of identifying relation instance between two entities given a corpus whereas Knowledge base modeling is the task of representing a knowledge base, in terms of relations between entities. This paper proposes…

Computation and Language · Computer Science 2020-11-20 Xiaoyu Chen , Rohan Badlani

Relation Extraction (RE) is a crucial task in Information Extraction, which entails predicting relationships between entities within a given sentence. However, extending pre-trained RE models to other languages is challenging, particularly…

Computation and Language · Computer Science 2023-04-21 Chiaming Hsu , Changtong Zan , Liang Ding , Longyue Wang , Xiaoting Wang , Weifeng Liu , Fu Lin , Wenbin Hu

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

The rapidly growth of biomedical literature creates challenges acquiring specific medical information. Current biomedical question-answering systems primarily focus on short-form answers, failing to provide comprehensive explanations…

Computation and Language · Computer Science 2026-01-05 Lovely Yeswanth Panchumarthi , Sumalatha Saleti , Sai Prasad Gudari , Atharva Negi , Praveen Raj Budime , Harsit Upadhya

The vast amount of biomedical information available today presents a significant challenge for investigators seeking to digest, process, and understand these findings effectively. Large Language Models (LLMs) have emerged as powerful tools…

Computation and Language · Computer Science 2024-07-19 Alexander R. Pelletier , Joseph Ramirez , Irsyad Adam , Simha Sankar , Yu Yan , Ding Wang , Dylan Steinecke , Wei Wang , Peipei Ping

The relation extraction (RE) in complex scenarios faces challenges such as diverse relation types and ambiguous relations between entities within a single sentence, leading to the poor performance of pure "text-in, text-out" language models…

Computation and Language · Computer Science 2024-09-04 Yuchen Shi , Guochao Jiang , Tian Qiu , Deqing Yang

The paradigm of retrieval-augmented generated (RAG) helps mitigate hallucinations of large language models (LLMs). However, RAG also introduces biases contained within the retrieved documents. These biases can be amplified in scenarios…

Computation and Language · Computer Science 2025-06-24 Bryan Li , Fiona Luo , Samar Haider , Adwait Agashe , Tammy Li , Runqi Liu , Muqing Miao , Shriya Ramakrishnan , Yuan Yuan , Chris Callison-Burch

Extracting fine-grained experimental findings from literature can provide dramatic utility for scientific applications. Prior work has developed annotation schemas and datasets for limited aspects of this problem, failing to capture the…

Computation and Language · Computer Science 2024-04-26 Aakanksha Naik , Bailey Kuehl , Erin Bransom , Doug Downey , Tom Hope