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Medical Image Analysis (MedIA) has emerged as a crucial tool in computer-aided diagnosis systems, particularly with the advancement of deep learning (DL) in recent years. However, well-trained deep models often experience significant…

Computer Vision and Pattern Recognition · Computer Science 2024-02-14 Ziwei Niu , Shuyi Ouyang , Shiao Xie , Yen-wei Chen , Lanfen Lin

For medical image segmentation, imagine if a model was only trained using MR images in source domain, how about its performance to directly segment CT images in target domain? This setting, namely generalizable cross-modality segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Ziqi Zhou , Lei Qi , Xin Yang , Dong Ni , Yinghuan Shi

Unsupervised Domain Adaptation (UDA) and domain generalization (DG) are two research areas that aim to tackle the lack of generalization of Deep Neural Networks (DNNs) towards unseen domains. While UDA methods have access to unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2023-04-25 Manuel Schwonberg , Fadoua El Bouazati , Nico M. Schmidt , Hanno Gottschalk

While recent advances in deep learning for surgical scene segmentation have demonstrated promising results on single-centre and single-imaging modality data, these methods usually do not generalise to unseen distribution (i.e., from other…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Mansoor Ali , Maksim Richards , Gilberto Ochoa-Ruiz , Sharib Ali

Limited amount of labelled training data are a common problem in medical imaging. This makes it difficult to train a well-generalised model and therefore often leads to failure in unknown domains. Hippocampus segmentation from magnetic…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 John Kalkhof , Camila González , Anirban Mukhopadhyay

As a fundamental imaging task, All-in-One Image Restoration (AiOIR) aims to achieve image restoration caused by multiple degradation patterns via a single model with unified parameters. Although existing AiOIR approaches obtain promising…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Junyu Fan , Chuanlin Liao , Yi Lin

Due to domain shifts across diverse medical imaging modalities, learned segmentation models often suffer significant performance degradation during deployment. We posit that these domain shifts can generally be categorized into two main…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane , Zhaolin Chen

Achieving domain generalization in medical imaging poses a significant challenge, primarily due to the limited availability of publicly labeled datasets in this domain. This limitation arises from concerns related to data privacy and the…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Ahmed Radwan , Islam Osman , Mohamed S. Shehata

Image normalization is a building block in medical image analysis. Conventional approaches are customarily utilized on a per-dataset basis. This strategy, however, prevents the current normalization algorithms from fully exploiting the…

Machine Learning · Computer Science 2020-10-06 Pierre-Luc Delisle , Benoit Anctil-Robitaille , Christian Desrosiers , Herve Lombaert

Domain shift happens in cross-domain scenarios commonly because of the wide gaps between different domains: when applying a deep learning model well-trained in one domain to another target domain, the model usually performs poorly. To…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Munan Ning , Cheng Bian , Dong Wei , Chenglang Yuan , Yaohua Wang , Yang Guo , Kai Ma , Yefeng Zheng

Single-domain generalization for object detection (S-DGOD) seeks to transfer learned representations from a single source domain to unseen target domains. While recent approaches have primarily focused on achieving feature invariance, they…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Zhenwei He , Hongsu Ni

The recent prevalence of deep neural networks has lead semantic segmentation networks to achieve human-level performance in the medical field when sufficient training data is provided. Such networks however fail to generalize when tasked…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Serban Stan , Mohammad Rostami

Single Domain Generalization (SDG) tackles the problem of training a model on a single source domain so that it generalizes to any unseen target domain. While this has been well studied for image classification, the literature on SDG object…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Vidit Vidit , Martin Engilberge , Mathieu Salzmann

Out-of-Domain (OOD) generalization is the ability of a model trained on one or more domains to generalize to unseen domains. In the ImageNet era of computer vision, evaluation sets for measuring a model's OOD performance were designed to be…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Prasanna Mayilvahanan , Roland S. Zimmermann , Thaddäus Wiedemer , Evgenia Rusak , Attila Juhos , Matthias Bethge , Wieland Brendel

Medical image segmentation plays an important role in clinical decision making, treatment planning, and disease tracking. However, it still faces two major challenges. On the one hand, there is often a ``soft boundary'' between foreground…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Mengqi Lei , Haochen Wu , Xinhua Lv , Xin Wang

Generalization to out-of-distribution (OOD) data is a capability natural to humans yet challenging for machines to reproduce. This is because most learning algorithms strongly rely on the i.i.d.~assumption on source/target data, which is…

Machine Learning · Computer Science 2022-08-15 Kaiyang Zhou , Ziwei Liu , Yu Qiao , Tao Xiang , Chen Change Loy

Convolutional neural networks (CNNs) have achieved exciting performance in joint segmentation of optic disc and optic cup on single-institution datasets. However, their clinical translation is hindered by two major challenges: limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yusong Xiao , Yuxuan Wu , Li Xiao , Gang Qu , Haiye Huo , Yu-Ping Wang

Magnification shift is a major obstacle to robust histopathology classification, because models trained on one imaging scale often generalize poorly to another. Here, we evaluated this problem on the BreaKHis dataset using a strict…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Ifeanyi Ezuma , Olusiji Medaiyese

Open Domain Generalization (ODG) is a challenging task as it not only deals with distribution shifts but also category shifts between the source and target datasets. To handle this task, the model has to learn a generalizable representation…

Computer Vision and Pattern Recognition · Computer Science 2023-12-11 Inseop Chung , KiYoon Yoo , Nojun Kwak

Both limited annotation and domain shift are prevalent challenges in medical image segmentation. Traditional semi-supervised segmentation and unsupervised domain adaptation methods address one of these issues separately. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Qinghe Ma , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao