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Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

Quantitative Methods · Quantitative Biology 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

Many existing interpretation methods are based on Partial Dependence (PD) functions that, for a pre-trained machine learning model, capture how a subset of the features affects the predictions by averaging over the remaining features.…

Machine Learning · Computer Science 2025-06-05 Jinyang Liu , Tessa Steensgaard , Marvin N. Wright , Niklas Pfister , Munir Hiabu

Patient motion is well-known for degrading image quality during medical imaging. Especially positron emission tomography (PET) is susceptible to motion due to its usually long scan times. In hybrid PET/MRI (magnetic resonance imaging),…

Medical Physics · Physics 2019-05-21 Lynn Johann Frohwein , Florian Büther , Klaus Peter Schäfers

Movement synchrony refers to the dynamic temporal connection between the motions of interacting people. The applications of movement synchrony are wide and broad. For example, as a measure of coordination between teammates, synchrony scores…

Computer Vision and Pattern Recognition · Computer Science 2022-08-03 Jicheng Li , Anjana Bhat , Roghayeh Barmaki

Robust characterization of dynamic causal interactions in multivariate biomedical signals is essential for advancing computational and algorithmic methods in biomedical imaging. Conventional approaches, such as Dynamic Bayesian Networks…

Signal Processing · Electrical Eng. & Systems 2026-02-17 Farwa Abbas , Wei Dai , Zoran Cvetkovic , Verity McClelland

Objective motor skill assessment plays a critical role in fields such as surgery, where proficiency is vital for certification and patient safety. Existing assessment methods, however, rely heavily on subjective human judgment, which…

Neurons and Cognition · Quantitative Biology 2025-02-20 Anil Kamat , Rahul Rahul , Anirban Dutta , Lora Cavuoto , Uwe Kruger , Harry Burke , Matthew Hackett , Jack Norfleet , Steven Schwaitzberg , Suvranu De

In recent years, single modality based gait recognition has been extensively explored in the analysis of medical images or other sensory data, and it is recognised that each of the established approaches has different strengths and…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Aite Zhao , Jianbo Li , Junyu Dong , Lin Qi , Qianni Zhang , Ning Li , Xin Wang , Huiyu Zhou

We present a multivariate functional mixed effects model for kinematic data from a large number of recreational runners. The runners' sagittal plane hip and knee angles are modelled jointly as a bivariate function with random effects…

Purpose: From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit passive and active mechanical properties, potentially coupled to electrical, chemical, and thermal properties. Experimental characterization of some…

Medical Physics · Physics 2024-06-25 Aude Loumeaud , Philippe Pouletaut , Sabine Bensamoun , Daniel George , Simon Chatelin

Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Jadie Adams , Shireen Elhabian

Autism Spectrum Disorders are associated with atypical movements, of which stereotypical motor movements (SMMs) interfere with learning and social interaction. The automatic SMM detection using inertial measurement units (IMU) remains…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Nastaran Mohammadian Rad , Seyed Mostafa Kia , Calogero Zarbo , Twan van Laarhoven , Giuseppe Jurman , Paola Venuti , Elena Marchiori , Cesare Furlanello

Modern mobile health (mHealth) assessment combines self-reported measures of participants' health experiences with passively collected health behavior data throughout the day. These data are collected across multiple measurement scales,…

Methodology · Statistics 2026-03-13 Debangan Dey , Rahul Ghosal , Kathleen Merikangas , Vadim Zipunnikov

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Tensor-based morphometry (TBM) aims at showing local differences in brain volumes with respect to a common template. TBM images are smooth but they exhibit (especially in diseased groups) higher values in some brain regions called lateral…

Background: Skin marker-based analysis of functional spinal movement is a promising method for quantifying longitudinal effects of treatment interventions in patients with spinal pathologies. However, observed day-to-day changes might not…

Analyzing longitudinal data in health studies is challenging due to sparse and error-prone measurements, strong within-individual correlation, missing data and various trajectory shapes. While mixed-effect models (MM) effectively address…

Methodology · Statistics 2024-07-11 Corentin Ségalas , Catherine Helmer , Robin Genuer , Cécile Proust-Lima

Decoding motor performance from brain signals offers promising avenues for adaptive deep brain stimulation (aDBS) for Parkinson's disease (PD). In a two-center cohort of 19 PD patients executing a drawing task, we decoded motor performance…

General movement assessment (GMA) of infant movement videos (IMVs) is an effective method for early detection of cerebral palsy (CP) in infants. We demonstrate in this paper that end-to-end trainable neural networks for image sequence…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Haomiao Ni , Yuan Xue , Liya Ma , Qian Zhang , Xiaoye Li , Xiaolei Huang

A functional linear discriminant analysis approach to classify a set of kinematic data (human movement curves of individuals performing different physical activities) is performed. Kinematic data, usually collected in linear acceleration or…

Methodology · Statistics 2024-02-09 M Carmen Aguilera-Morillo , Ana M Aguilera

To assess the integrity of the developing nervous system, the Prechtl general movement assessment (GMA) is recognized for its clinical value in diagnosing neurological impairments in early infancy. GMA has been increasingly augmented…

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