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Evaluating neurological disorders such as Parkinson's disease (PD) is a challenging task that requires the assessment of several motor and non-motor functions. In this paper, we present an end-to-end deep learning framework to measure PD…

Computer Vision and Pattern Recognition · Computer Science 2020-12-25 Amirhossein Dadashzadeh , Alan Whone , Michal Rolinski , Majid Mirmehdi

One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…

Machine Learning · Computer Science 2019-04-26 Jann Goschenhofer , Franz MJ Pfister , Kamer Ali Yuksel , Bernd Bischl , Urban Fietzek , Janek Thomas

We use autoregressive hidden Markov models and a time-frequency approach to create meaningful quantitative descriptions of behavioral characteristics of cerebellar ataxias from wearable inertial sensor data gathered during movement.…

Neurons and Cognition · Quantitative Biology 2021-08-23 Karin C. Knudson , Anoopum S. Gupta

Shape-constrained functional data encompass a wide array of application fields, such as activity profiling, growth curves, healthcare and mortality. Most existing methods for general functional data analysis often ignore that such data are…

Methodology · Statistics 2024-08-13 Poorbita Kundu , Hans-Georg Müller

Atypical Parkinsonian Disorders (APD), also known as Parkinson-plus syndrome, are a group of neurodegenerative diseases that include progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). In the early stages, overlapping…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Mengyu Li , Ingibjörg Kristjánsdóttir , Thilo van Eimeren , Kathrin Giehl , Lotta M. Ellingsen , the ASAP Neuroimaging Initiative

Sleep behaviour and in-bed movements contain rich information on the neurophysiological health of people, and have a direct link to the general well-being and quality of life. Standard clinical practices rely on polysomnography for sleep…

Signal Processing · Electrical Eng. & Systems 2023-01-10 Omar Elnaggar , Roselina Arelhi , Frans Coenen , Andrew Hopkinson , Lyndon Mason , Paolo Paoletti

Reliable fall detection in elderly care requires monitoring systems that are not only accurate but also capable of producing stable, interpretable explanations of motion dynamics, a requirement that existing post hoc explainability methods…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Mohammad Saleh , Azadeh Tabatabaei

The rapid advancement of medical technology has led to an exponential increase in multi-modal medical data, including imaging, genomics, and electronic health records (EHRs). Graph neural networks (GNNs) have been widely used to represent…

Quantitative Methods · Quantitative Biology 2024-10-03 Favour Nerrise , Alice Louise Heiman , Ehsan Adeli

Quantitative estimation of human joint motion in daily living spaces is essential for early detection and rehabilitation tracking of neuromusculoskeletal disorders (e.g., Parkinson's) and mitigating trip and fall risks for older adults.…

Human-Computer Interaction · Computer Science 2025-03-24 Yiwen Dong , Jessica Rose , Hae Young Noh

Sparse functional data arise when measurements are observed infrequently and at irregular time points for each subject, often in the presence of measurement error. These characteristics introduce additional challenges for functional…

Methodology · Statistics 2026-03-20 Uche Mbaka , Jiguo Cao , Michelle Carey

Parkinson's disease (PD) has been found to affect 1 out of every 1000 people, being more inclined towards the population above 60 years. Leveraging wearable-systems to find accurate biomarkers for diagnosis has become the need of the hour,…

Machine Learning · Computer Science 2023-04-20 Poojaa C , John Sahaya Rani Alex

Parkinson's disease (PD) is a chronic and complex neurodegenerative disorder influenced by genetic, clinical, and lifestyle factors. Predicting this disease early is challenging because it depends on traditional diagnostic methods that face…

Machine Learning · Computer Science 2026-04-21 Md Mezbahul Islam , John Michael Templeton , Masrur Sobhan , Christian Poellabauer , Ananda Mohan Mondal

Neurological disorders, including stroke, spinal cord injuries, multiple sclerosis, and Parkinson's disease, generally lead to diminished upper extremity (UE) function, impacting individuals' independence and quality of life. Traditional…

Signal Processing · Electrical Eng. & Systems 2024-08-02 Tommaso Proietti , Andrea Bandini

Growth charts are widely used in pediatric care for assessing childhood body size measurements (e.g., height or weight). The existing growth charts screen one body size at a single given age. However, when a child has multiple measures over…

Applications · Statistics 2015-09-18 Wenfei Zhang , Ying Wei

Wearable devices are often used in clinical and epidemiological studies to monitor physical activity behavior and its influence on health outcomes. These devices are worn over multiple days to record activity patterns, such as step counts…

Methodology · Statistics 2025-11-14 Heyang Ji , Lan Xue , Ufuk Beyaztas , Roger S. Zoh , Jeff Goldsmith , Mark E. Benden , Carmen D. Tekwe

Physical activity (PA) is significantly associated with many health outcomes. The wide usage of wearable accelerometer-based activity trackers in recent years has provided a unique opportunity for in-depth research on PA and its relations…

Physical activity is crucial for human health. With the increasing availability of large-scale mobile health data, strong associations have been found between physical activity and various diseases. However, accurately capturing this…

Methodology · Statistics 2026-01-19 Xiaojing Sun , Bingxin Zhao , Fei Xue

In clinical practice and biomedical research, measurements are often collected sparsely and irregularly in time while the data acquisition is expensive and inconvenient. Examples include measurements of spine bone mineral density, cancer…

Machine Learning · Statistics 2021-08-05 Łukasz Kidziński , Trevor Hastie

Work-related musculoskeletal disorders (WMSDs) remain one of the major occupational safety and health problems in the European Union nowadays. Thus, continuous tracking of workers' exposure to the factors that may contribute to their…

Robotics · Computer Science 2021-11-12 Marta Lorenzini , Wansoo Kim , Arash Ajoudani

MRI, a widespread non-invasive medical imaging modality, is highly sensitive to patient motion. Despite many attempts over the years, motion correction remains a difficult problem and there is no general method applicable to all situations.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Oscar Dabrowski , Jean-Luc Falcone , Antoine Klauser , Julien Songeon , Michel Kocher , Bastien Chopard , François Lazeyras , Sébastien Courvoisier