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3D brain MRI studies often examine subtle morphometric differences between cohorts that are hard to detect visually. Given the high cost of MRI acquisition, these studies could greatly benefit from image syntheses, particularly…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Binxu Li , Wei Peng , Mingjie Li , Ehsan Adeli , Kilian M. Pohl

The work proposes a novel deep-learning framework for the synthesis of three-dimensional MRI volumes from corresponding 3D ultrasound images of the brain, leveraging a modified iteration of the Pix2Pix Generative Adversarial Network (GAN)…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Shubham Singh , Mrunal Bewoor , Ammar Ranapurwala , Satyam Rai , Sheetal Patil

Multimodal machine learning (MML) is rapidly reshaping the way mental-health disorders are detected, characterized, and longitudinally monitored. Whereas early studies relied on isolated data streams -- such as speech, text, or wearable…

Machine Learning · Computer Science 2025-06-25 Zahraa Al Sahili , Ioannis Patras , Matthew Purver

Medicine is inherently multimodal and multitask, with diverse data modalities spanning text, imaging. However, most models in medical field are unimodal single tasks and lack good generalizability and explainability. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Lijian Xu , Hao Sun , Ziyu Ni , Hongsheng Li , Shaoting Zhang

Generative Artificial Intelligence (GenAI) is taking the world by storm. It promises transformative opportunities for advancing and disrupting existing practices, including healthcare. From large language models (LLMs) for clinical note…

Artificial Intelligence · Computer Science 2025-10-29 Gang Chen , Changshuo Liu , Gene Anne Ooi , Marcus Tan , Zhongle Xie , Jianwei Yin , James Wei Luen Yip , Wenqiao Zhang , Jiaqi Zhu , Beng Chin Ooi

The advent of Unified Multimodal Models (UMMs) signals a paradigm shift in artificial intelligence, moving from passive perception to active, cross-modal generation. Despite their unprecedented ability to synthesize information, a critical…

Artificial Intelligence · Computer Science 2026-01-15 Jingxuan Wei , Caijun Jia , Xi Bai , Xinglong Xu , Siyuan Li , Linzhuang Sun , Bihui Yu , Conghui He , Lijun Wu , Cheng Tan

Generative adversarial networks (GANs) have provided promising data enrichment solutions by synthesizing high-fidelity images. However, generating large sets of labeled images with new anatomical variations remains unexplored. We propose a…

Image and Video Processing · Electrical Eng. & Systems 2020-08-03 Sina Amirrajab , Samaneh Abbasi-Sureshjani , Yasmina Al Khalil , Cristian Lorenz , Juergen Weese , Josien Pluim , Marcel Breeuwer

Machine learning holds promise for advancing clinical decision support, yet it remains unclear when multimodal learning truly helps in practice, particularly under modality missingness and fairness constraints. In this work, we conduct a…

Machine Learning · Computer Science 2026-03-02 Kejing Yin , Haizhou Xu , Wenfang Yao , Chen Liu , Zijie Chen , Yui Haang Cheung , William K. Cheung , Jing Qin

While multi-modal learning has been widely used for MRI reconstruction, it relies on paired multi-modal data which is difficult to acquire in real clinical scenarios. Especially in the federated setting, the common situation is that several…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Yunlu Yan , Chun-Mei Feng , Yuexiang Li , Rick Siow Mong Goh , Lei Zhu

Sharing diverse genomic and other biomedical datasets is critical to advance scientific discoveries and their equitable translation to improve human health. However, data sharing remains challenging in the context of legacy datasets,…

Generation of images containing multiple humans, performing complex actions, while preserving their facial identities, is a significant challenge. A major factor contributing to this is the lack of a dedicated benchmark. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shubhankar Borse , Seokeon Choi , Sunghyun Park , Jeongho Kim , Shreya Kadambi , Risheek Garrepalli , Sungrack Yun , Munawar Hayat , Fatih Porikli

Recent advancements in generative models have revolutionized the field of artificial intelligence, enabling the creation of highly-realistic and detailed images. In this study, we propose a novel Mask Conditional Text-to-Image Generative…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Rami Skaik , Leonardo Rossi , Tomaso Fontanini , Andrea Prati

Affective computing faces a major challenge: the lack of high-quality, diverse depth facial datasets for recognizing subtle emotional expressions. We propose a framework for synthetic depth face generation using an optimized GAN with…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Seyed Muhammad Hossein Mousavi , S. Younes Mirinezhad

The integration of multimodal Electronic Health Records (EHR) data has significantly advanced clinical predictive capabilities. Existing models, which utilize clinical notes and multivariate time-series EHR data, often fall short of…

Computation and Language · Computer Science 2025-02-27 Yinghao Zhu , Changyu Ren , Zixiang Wang , Xiaochen Zheng , Shiyun Xie , Junlan Feng , Xi Zhu , Zhoujun Li , Liantao Ma , Chengwei Pan

Large language models (LLMs) in biomedicine face a fundamental conflict between static parameter knowledge and the dynamic nature of clinical evidence. Retrieval-Augmented Generation (RAG) addresses this by grounding generation in external…

Other Quantitative Biology · Quantitative Biology 2025-12-19 Jiawei He , Boya Zhang , Hossein Rouhizadeh , Yingjian Chen , Rui Yang , Jin Lu , Xudong Chen , Nan Liu , Douglas Teodoro

Medical image segmentation plays a crucial role in AI-assisted diagnostics, surgical planning, and treatment monitoring. Accurate and robust segmentation models are essential for enabling reliable, data-driven clinical decision making…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Sachin Dudda Nagaraju , Ashkan Moradi , Bendik Skarre Abrahamsen , Mattijs Elschot

Explainable Artificial Intelligence (XAI) has been presented as the critical component for unlocking the potential of machine learning in mental health screening (MHS). However, a persistent lab-to-clinic gap remains. Current XAI…

Computation and Language · Computer Science 2025-10-17 Ratna Kandala , Akshata Kishore Moharir , Divya Arvinda Nayak

Multi-modal medical images provide complementary soft-tissue characteristics that aid in the screening and diagnosis of diseases. However, limited scanning time, image corruption and various imaging protocols often result in incomplete…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Yue Zhang , Chengtao Peng , Qiuli Wang , Dan Song , Kaiyan Li , S. Kevin Zhou

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Julian Schön , Raghavendra Selvan , Lotte Nygård , Ivan Richter Vogelius , Jens Petersen