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The complexity and size of state-of-the-art cell models have significantly increased in part due to the requirement that these models possess complex cellular functions which are thought--but not necessarily proven--to be important. Modern…

Neurons and Cognition · Quantitative Biology 2018-11-22 J. L. Hart , P. A. Gremaud , T. David

Differential sensitivity measures provide valuable tools for interpreting complex computational models used in applications ranging from simulation to algorithmic prediction. Taking the derivative of the model output in direction of a model…

Computation · Statistics 2024-10-03 Silvana M. Pesenti , Pietro Millossovich , Andreas Tsanakas

Reliability sensitivity analysis is concerned with measuring the influence of a system's uncertain input parameters on its probability of failure. Statistically dependent inputs present a challenge in both computing and interpreting these…

Applications · Statistics 2023-06-21 Max Ehre , Iason Papaioannou , Daniel Straub

In predictive modeling with simulation or machine learning, it is critical to accurately assess the quality of estimated values through output analysis. In recent decades output analysis has become enriched with methods that quantify the…

Methodology · Statistics 2023-10-27 Kimia Vahdat , Sara Shashaani

A new method for estimating Sobol' indices is proposed. The new method makes use of 3 independent input vectors rather than the usual 2. It attains much greater accuracy on problems where the target Sobol' index is small, even outperforming…

Methodology · Statistics 2012-04-24 Art B. Owen

We introduce a new method to jointly reduce the dimension of the input and output space of a function between high-dimensional spaces. Choosing a reduced input subspace influences which output subspace is relevant and vice versa.…

Machine Learning · Statistics 2025-04-01 Qiao Chen , Elise Arnaud , Ricardo Baptista , Olivier Zahm

In many ranking problems, some particular aspects of the addressed situation should be taken into account in the aggregation process. An example is the presence of correlations between criteria, which may introduce bias in the derived…

Signal Processing · Electrical Eng. & Systems 2020-12-09 Guilherme D. Pelegrina , Leonardo T. Duarte , Michel Grabisch , João M. T. Romano

Drawing parallels with the way biological networks are studied, we adapt the treatment--control paradigm to explainable artificial intelligence research and enrich it through multi-parametric input alterations. In this study, we propose a…

Machine Learning · Statistics 2026-01-16 Pavel Kharyuk , Sergey Matveev , Ivan Oseledets

Every computer model depends on numerical input parameters that are chosen according to mostly conservative but rigorous numerical or empirical estimates. These parameters could for example be the step size for time integrators, a seed for…

Computational Physics · Physics 2020-09-11 Matthias Frey , Andreas Adelmann

The method of derivative based global sensitivity measures (DGSM) has recently become popular among practitioners. It has a strong link with the Morris screening method and Sobol' sensitivity indices and has several advantages over them.…

Statistics Theory · Mathematics 2023-12-05 Serge Kucherenko , Bertrand Iooss

Reliability-oriented sensitivity analysis aims at combining both reliability and sensitivity analyses by quantifying the influence of each input variable of a numerical model on a quantity of interest related to its failure. In particular,…

Statistics Theory · Mathematics 2022-10-25 Julien Demange-Chryst , François Bachoc , Jérôme Morio

Sensitivity analysis of a numerical model, for instance simulating physical phenomena, is useful to quantify the influence of the inputs on the model responses. This paper proposes a new sensitivity index, based upon the modification of the…

Given a bivariate random pair $(X,Y)$, a natural problem is to estimate, from a single sample $(X_i,Y_i)_{1\le i\le n}$, quantities such as $\mathbb{E}\left[ \mathbb{E}[ Y\mid X ]^2 \right]$. More broadly, sensitivity indices are designed…

Statistics Theory · Mathematics 2026-03-25 Reda Chhaibi , Fabrice Gamboa , Clément Pellegrini

In this paper, we study sensitivity indices for independent groups of variables and we look at the particular case of block-additive models. We show in this case that most of the Sobol indices are equal to zero and that Shapley effects can…

Statistics Theory · Mathematics 2018-12-12 Baptiste Broto , François Bachoc , Marine Depecker , Jean-Marc Martinez

We propose a holistic framework for constructing sensitivity measures for any elicitable functional $T$ of a response variable. The sensitivity measures, termed score-based sensitivities, are constructed via scoring functions that are…

Applications · Statistics 2023-02-03 Tobias Fissler , Silvana M. Pesenti

We describe a mathematical language for determining all possible patterns of contextuality in the dependence of stochastic outputs of a system on its deterministic inputs. The central notion is that of all possible couplings for…

Mathematical Physics · Physics 2015-01-27 Ehtibar N. Dzhafarov , Janne V. Kujala

The so-called polynomial chaos expansion is widely used in computer experiments. For example, it is a powerful tool to estimate Sobol' sensitivity indices. In this paper, we consider generalized chaos expansions built on general tensor…

Statistics Theory · Mathematics 2019-06-25 O Roustant , F. Gamboa , B Iooss

In the field of computer experiments sensitivity analysis aims at quantifying the relative importance of each input parameter (or combinations thereof) of a computational model with respect to the model output uncertainty. Variance…

Computation · Statistics 2014-05-23 Bruno Sudret , Chu Van Mai

Global sensitivity analysis (GSA) is a recommended step in the use of computer simulation models. GSA quantifies the relative importance of model inputs on outputs (Factor Ranking), identifies inputs that could be fixed, thus simplifying…

Methodology · Statistics 2025-10-27 Ken Newman , Shaini Naha , Leah Jackson-Blake , Cairistiona Topp , Miriam Glendell , Adam Butler

Bayesian Additive Regression Trees (BART) are non-parametric models that can capture complex exogenous variable effects. In any regression problem, it is often of interest to learn which variables are most active. Variable activity in BART…

Methodology · Statistics 2020-09-16 Akira Horiguchi , Matthew T. Pratola , Thomas J. Santner
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