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We present a numerical approximation technique for the analysis of continuous-time Markov chains that describe networks of biochemical reactions and play an important role in the stochastic modeling of biological systems. Our approach is…

Quantitative Methods · Quantitative Biology 2010-05-06 Thomas A. Henzinger , Maria Mateescu , Linar Mikeev , Verena Wolf

We consider numerical methods for the Poisson-Nernst-Planck-Cahn-Hilliard (PNPCH) equations with steric interactions. We propose a novel energy stable numerical scheme that respects mass conservation and positivity at the discrete level.…

Numerical Analysis · Mathematics 2021-02-03 Yiran Qian , Cheng Wang , Shenggao Zhou

We are concerned in designing a suitable numerical scheme based on the equal-order hybrid high-order (HHO) method for the linear parabolic integro-differential equations. The spatial discretization is made using the equal-order HHO method…

Numerical Analysis · Mathematics 2026-04-17 Achyuta Ranjan Dutta Mohapatra

In this paper, we provide a detailed theoretical analysis of the numerical scheme introduced in J. Comput. Phys. 436 (2021) 110253 for the reaction kinetics of a class of chemical reaction networks that satisfies detailed balance condition.…

Numerical Analysis · Mathematics 2024-02-07 Chun Liu , Cheng Wang , Yiwei Wang

In this paper, we derive two bound-preserving and mass-conserving schemes based on the fractional-step method and high-order compact (HOC) finite difference method for nonlinear convection-dominated diffusion equations. We split the…

Numerical Analysis · Mathematics 2024-09-16 Baolin Kuang , Hongfei Fu , Shusen Xie

In this paper, a class of arbitrarily high-order linear momentum-preserving and energy-preserving schemes are proposed, respectively, for solving the regularized long-wave equation. For the momentum-preserving scheme, the key idea is based…

Numerical Analysis · Mathematics 2021-12-07 Chaolong Jiang , Xu Qian , Songhe Song , Jin Cui

Many differential equations with physical backgrounds are described as gradient systems, which are evolution equations driven by the gradient of some functionals, and such problems have energy conservation or dissipation properties. For…

Numerical Analysis · Mathematics 2023-08-07 Tomoya Kemmochi

A novel class of explicit high-order energy-preserving methods are proposed for general Hamiltonian partial differential equations with non-canonical structure matrix. When the energy is not quadratic, it is firstly done that the original…

Numerical Analysis · Mathematics 2020-06-02 Chaolong Jiang , Yushun Wang , Yuezheng Gong

We present a class of new explicit and stable numerical algorithms to solve the spatially discretized linear heat or diffusion equation. After discretizing the space and the time variables like conventional finite difference methods, we do…

Numerical Analysis · Mathematics 2021-04-27 Endre Kovács

In this paper, we design, analyze, and numerically validate positive and energy-dissipating schemes for solving the time-dependent multi-dimensional system of Poisson-Nernst-Planck (PNP) equations, which has found much use in the modeling…

Numerical Analysis · Mathematics 2020-02-24 Hailiang Liu , Wumaier Maimaitiyiming

We construct a positivity-preserving Lie--Trotter splitting scheme with finite difference discretization in space for approximating the solutions to a class of nonlinear stochastic heat equations with multiplicative space-time white noise.…

Numerical Analysis · Mathematics 2023-02-20 Charles-Edouard Bréhier , David Cohen , Johan Ulander

This paper addresses the problem of model reduction for dynamical system models that describe biochemical reaction networks. Inherent in such models are properties such as stability, positivity and network structure. Ideally these…

Optimization and Control · Mathematics 2014-03-17 Aivar Sootla , James Anderson

In this paper, we develop a family of high order asymptotic preserving schemes for some discrete-velocity kinetic equations under a diffusive scaling, that in the asymptotic limit lead to macroscopic models such as the heat equation, the…

Numerical Analysis · Mathematics 2013-06-04 Juhi Jang , Fengyan Li , Jing-Mei Qiu , Tao Xiong

We introduce a (linear) positive and asymptotic preserving method or solving the one-group radiation transport equation. The approximation in space is discretization agnostic: the space approximation can be done with continuous or…

Numerical Analysis · Mathematics 2019-05-10 Jean-Luc Guermond , Bojan Popov , Jean Ragusa

Non-local systems of conservation laws play a crucial role in modeling flow mechanisms across various scenarios. The well-posedness of such problems is typically established by demonstrating the convergence of robust first-order schemes.…

Numerical Analysis · Mathematics 2025-01-07 Nikhil Manoj , G. D. Veerappa Gowda , Sudarshan Kumar K

Symmetry preserving difference schemes approximating second and third order ordinary differential equations are presented. They have the same three or four-dimensional symmetry groups as the original differential equations. The new…

Mathematical Physics · Physics 2009-11-11 A. Bourlioux , C Cyr-Gagnon , P Winternitz

In this paper, a novel computational technique for finite discrete approximation of continuous dynamical systems suitable for a significant class of biochemical dynamical systems is introduced. The method is parameterized in order to affect…

Systems and Control · Computer Science 2011-09-09 L. Brim , J. Fabriková , S. Dražan , D. Šafránek

In this paper, we are interested in constructing a scheme solving compressible Navier--Stokes equations, with desired properties including high order spatial accuracy, conservation, and positivity-preserving of density and internal energy…

Numerical Analysis · Mathematics 2023-09-13 Chen Liu , Xiangxiong Zhang

In this paper, we design and analyze third order positivity-preserving discontinuous Galerkin (DG) schemes for solving the time-dependent system of Poisson--Nernst--Planck (PNP) equations, which has found much use in diverse applications.…

Numerical Analysis · Mathematics 2022-01-26 Hailiang Liu , Zhongming Wang , Peimeng Yin , Hui Yu

We derive high-order compact finite difference schemes for option pricing in stochastic volatility models on non-uniform grids. The schemes are fourth-order accurate in space and second-order accurate in time for vanishing correlation. In…

Computational Finance · Quantitative Finance 2014-05-12 Bertram Düring , Michel Fournié , Christof Heuer