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Introduction: Cases of throat cancer are rising worldwide. With survival decreasing significantly at later stages, early detection is vital. Artificial intelligence (AI) and machine learning (ML) have the potential to detect throat cancer…

Machine Learning · Computer Science 2025-05-14 Mary Paterson , James Moor , Luisa Cutillo

Fairness is an increasingly important concern as machine learning models are used to support decision making in high-stakes applications such as mortgage lending, hiring, and prison sentencing. This paper introduces a new open source Python…

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

Time series analysis has emerged as an important tool for improving patient diagnosis and management in healthcare applications. However, these applications commonly face two critical challenges: time misalignment and data sparsity.…

Machine Learning · Statistics 2025-09-25 Dohyun Ku , Catherine D. Chong , Visar Berisha , Todd J. Schwedt , Jing Li

We establish a broad methodological foundation for mixed-integer optimization with learned constraints. We propose an end-to-end pipeline for data-driven decision making in which constraints and objectives are directly learned from data…

Optimization and Control · Mathematics 2023-10-30 Donato Maragno , Holly Wiberg , Dimitris Bertsimas , S. Ilker Birbil , Dick den Hertog , Adejuyigbe Fajemisin

The escalating integration of machine learning in high-stakes fields such as healthcare raises substantial concerns about model fairness. We propose an interpretable framework - Fairness-Aware Interpretable Modeling (FAIM), to improve model…

Machine Learning · Computer Science 2024-03-11 Mingxuan Liu , Yilin Ning , Yuhe Ke , Yuqing Shang , Bibhas Chakraborty , Marcus Eng Hock Ong , Roger Vaughan , Nan Liu

We introduce milearn, a Python package for multi-instance learning (MIL) that follows the familiar scikit-learn fit/predict interface while providing a unified framework for both classical and neural-network-based MIL algorithms for…

Machine Learning · Computer Science 2025-12-02 Dmitry Zankov , Pavlo Polishchuk , Michal Sobieraj , Mario Barbatti

Medical imaging is critical for diagnostics, but clinical adoption of advanced AI-driven imaging faces challenges due to patient variability, image artifacts, and limited model generalization. While deep learning has transformed image…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Abdul-mojeed Olabisi Ilyas , Adeleke Maradesa , Jamal Banzi , Jianpan Huang , Henry K. F. Mak , Kannie W. Y. Chan

Computerized Adaptive Testing (CAT) is a widely used technology for evaluating learners' proficiency in online education platforms. By leveraging prior estimates of proficiency to select questions and updating the estimates iteratively…

Information Retrieval · Computer Science 2025-12-24 Mi Tian , Kun Zhang , Fei Liu , Jinglong Li , Yuxin Liao , Chenxi Bai , Zhengtao Tan , Le Wu , Richang Hong

Healthcare industries face challenges when experiencing rare diseases due to limited samples. Artificial Intelligence (AI) communities overcome this situation to create synthetic data which is an ethical and privacy issue in the medical…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Al Amin , Kamrul Hasan , Saleh Zein-Sabatto , Liang Hong , Sachin Shetty , Imtiaz Ahmed , Tariqul Islam

Deep learning models show promise in digital pathology, but their opaque decision-making processes limit trust and clinical adoption. To address this challenge, we present HIPPO, an explainable AI method for analyzing weakly-supervised…

Tissues and Organs · Quantitative Biology 2025-12-10 Jakub R. Kaczmarzyk , Chanwoo Kim , Soham Gadgil , Deepika Savant , Zhen Zhao , Joel H. Saltz , Su-In Lee , Peter K. Koo

A longstanding challenge surrounding deep learning algorithms is unpacking and understanding how they make their decisions. Explainable Artificial Intelligence (XAI) offers methods to provide explanations of internal functions of algorithms…

Artificial Intelligence · Computer Science 2022-08-16 Amin Nayebi , Sindhu Tipirneni , Brandon Foreman , Chandan K. Reddy , Vignesh Subbian

The potential risk of AI systems unintentionally embedding and reproducing bias has attracted the attention of machine learning practitioners and society at large. As policy makers are willing to set the standards of algorithms and AI…

Artificial Intelligence · Computer Science 2020-03-17 Boris Ruf , Chaouki Boutharouite , Marcin Detyniecki

The absence of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. Although various methods of explainable artificial intelligence (XAI) have been suggested, there is a lack of literature that…

Machine Learning · Computer Science 2023-06-22 Aida Brankovic , David Cook , Jessica Rahman , Wenjie Huang , Sankalp Khanna

Machine learning (ML) research has yielded powerful tools for training accurate prediction models despite complex multivariate associations (e.g. interactions and heterogeneity). In fields such as medicine, improved interpretability of ML…

Machine Learning · Computer Science 2021-04-28 Robert Zhang , Rachael Stolzenberg-Solomon , Shannon M. Lynch , Ryan J. Urbanowicz

Imbalanced music genre classification is a crucial task in the Music Information Retrieval (MIR) field for identifying the long-tail, data-poor genre based on the related music audio segments, which is very prevalent in real-world…

Sound · Computer Science 2022-09-12 Xiaokai Liu , Menghua Zhang

Atom probe tomography (APT) is a burgeoning characterization technique that provides compositional mapping of materials in three-dimensions at near-atomic scale. Since its significant expansion in the past 30 years, we estimate that one…

Materials Science · Physics 2025-04-22 Yue Li , Ye Wei , Alaukik Saxena , Markus Kühbach , Christoph Freysoldt , Baptiste Gault

This paper describes MAIA, a Multimodal Automated Interpretability Agent. MAIA is a system that uses neural models to automate neural model understanding tasks like feature interpretation and failure mode discovery. It equips a pre-trained…

Artificial Intelligence · Computer Science 2025-02-13 Tamar Rott Shaham , Sarah Schwettmann , Franklin Wang , Achyuta Rajaram , Evan Hernandez , Jacob Andreas , Antonio Torralba

Survival analysis, a foundational tool for modeling time-to-event data, has seen growing integration with machine learning (ML) approaches to handle the complexities of censored data and time-varying risks. Despite these advances,…

Quantitative Methods · Quantitative Biology 2025-02-05 Giovanni Birolo , Ivan Rossi , Flavio Sartori , Cesare Rollo , Tiziana Sanavia , Piero Fariselli

Transparency in Machine Learning (ML), attempts to reveal the working mechanisms of complex models. Transparent ML promises to advance human factors engineering goals of human-centered AI in the target users. From a human-centered design…

Human-Computer Interaction · Computer Science 2022-10-03 Haomin Chen , Catalina Gomez , Chien-Ming Huang , Mathias Unberath