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Mental disorders are among the leading causes of disability worldwide. The first step in treating these conditions is to obtain an accurate diagnosis, but the absence of established clinical tests makes this task challenging. Machine…

Signal Processing · Electrical Eng. & Systems 2021-10-13 Caroline L. Alves , Aruane M. Pineda , Kirstin Roster , Christiane Thielemann , Francisco A. Rodrigues

Recent advances in deep learning have enabled increasingly accurate electroencephalography (EEG)-based classification of Major Depressive Disorder (MDD), but the decision-making processes of high-capacity models remain difficult to…

Machine Learning · Computer Science 2026-05-29 Antonia Šarčević , Nikolina Frid

Many time series, particularly health data streams, can be best understood as a sequence of phenomenon or events, which we call \textit{motifs}. A time series motif is a short trace segment which may implicitly capture an underlying…

Machine Learning · Computer Science 2025-05-26 Josephine Lamp , Mark Derdzinski , Christopher Hannemann , Sam Hatfield , Joost van der Linden

Biomedical signals aid in the diagnosis of different disorders and abnormalities. When targeting lossy compression of such signals, the medically relevant information that lies within the data should maintain its accuracy and thus its…

Information Theory · Computer Science 2024-10-30 Hoda Daou , Fabrice Labeau

Reliable diagnosis of depressive disorder is essential for both optimal treatment and prevention of fatal outcomes. In this study, we aimed to elucidate the effectiveness of two non-linear measures, Higuchi Fractal Dimension (HFD) and…

This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

Depression is a widespread mental health disorder, yet its automatic detection remains challenging. Prior work has explored unimodal and multimodal approaches, with multimodal systems showing promise by leveraging complementary signals.…

Artificial Intelligence · Computer Science 2026-03-24 Annisaa Fitri Nurfidausi , Eleonora Mancini , Paolo Torroni

Depression and suicidality affect cognitive and emotional processes, yet objective, task-evoked neural readouts of mental health remain limited. We investigated the spatiotemporal dynamics of affective semantic processing using multivariate…

In this paper, we investigate stable patterns of electroencephalogram (EEG) over time for emotion recognition using a machine learning approach. Up to now, various findings of activated patterns associated with different emotions have been…

Human-Computer Interaction · Computer Science 2016-01-12 Wei-Long Zheng , Jia-Yi Zhu , Bao-Liang Lu

While EEG features differentiate Major Depressive Disorder (MDD) from healthy controls (HC), their clinical utility as biomarkers depends on a monotonic trajectory across the disease spectrum, from the acute (AC) phase to the maintenance…

Neurons and Cognition · Quantitative Biology 2026-03-05 Feng Yan , Xuteng Wang , Shuyu Yang , Yue Zhao , Xiaobin Wong , Zhiren Wang

Electroencephalography (EEG) serves as an effective diagnostic tool for mental disorders and neurological abnormalities. Enhanced analysis and classification of EEG signals can help improve detection performance. A new approach is examined…

Signal Processing · Electrical Eng. & Systems 2020-02-11 Lubna Shibly Mokatren , Rashid Ansari , Ahmet Enis Cetin , Alex D Leow , Heide Klumpp , Olusola Ajilore , Fatos Yarman Vural

A wide variety of methods have been developed for identifying depression, but they focus primarily on measuring the degree to which individuals are suffering from depression currently. In this work we explore the possibility of predicting…

Machine Learning · Computer Science 2022-03-22 Guansong Pang , Ngoc Thien Anh Pham , Emma Baker , Rebecca Bentley , Anton van den Hengel

Biomarkers of Major Depressive Disorder(MDD), its phases and forms have long been sought. Research indicates that the complexity measures of the cortical electrical activity (EEG) might be candidates for this role. To examine whether the…

Neurons and Cognition · Quantitative Biology 2019-12-19 Čukić Milena , Stokić Miodrag , Radenković Slavoljub , Ljubisavljević Miloš , Simić Slobodan , Danka Savić

Emotional recognition through exploring the electroencephalography (EEG) characteristics has been widely performed in recent studies. Nonlinear analysis and feature extraction methods for understanding the complex dynamical phenomena are…

Signal Processing · Electrical Eng. & Systems 2022-05-10 Yan Yan , Xuankun Wu , Chengdong Li , Yini He , Zhicheng Zhang , Huihui Li , Ang Li , Lei Wang

Electroencephalography (EEG) is a method of recording brain activity that shows significant promise in applications ranging from disease classification to emotion detection and brain-computer interfaces. Recent advances in deep learning…

Machine Learning · Computer Science 2026-01-15 Amarpal Sahota , Navid Mohammadi Foumani , Raul Santos-Rodriguez , Zahraa S. Abdallah

Epilepsy is one of the most common neurological disorders, affecting about 1% of the population at all ages. Detecting the development of epilepsy, i.e., epileptogenesis (EPG), before any seizures occur could allow for early interventions…

Machine Learning · Computer Science 2020-06-18 Diyuan Lu , Sebastian Bauer , Valentin Neubert , Lara Sophie Costard , Felix Rosenow , Jochen Triesch

Robust and interpretable dementia diagnosis from noisy, non-stationary electroencephalography (EEG) is clinically essential yet remains challenging. To this end, we propose SeeGraph, a Sparse-Explanatory dynamic EEG-graph network that…

Signal Processing · Electrical Eng. & Systems 2026-03-19 Fengcheng Wu , Zhenxi Song , Guoyang Xu , Kaisong Hu , Zirui Wang , Yi Guo , Zhiguo Zhang

Motivated behaviour relies on the brain's capacity to evaluate effort and reward. Dysregulation within these processes contributes to a spectrum of conditions, from hyperactivity in attention-deficit/hyperactivity disorder (ADHD) to…

Neurons and Cognition · Quantitative Biology 2026-04-20 Nam Trinh

Despite extensive standardization, diagnostic interviews for mental health disorders encompass substantial subjective judgment. Previous studies have demonstrated that EEG-based neural measures can function as reliable objective correlates…

Machine Learning · Computer Science 2020-11-19 Garrett Honke , Irina Higgins , Nina Thigpen , Vladimir Miskovic , Katie Link , Sunny Duan , Pramod Gupta , Julia Klawohn , Greg Hajcak

Major Depressive Disorder (MDD) is a highly prevalent mental health condition, and a deeper understanding of its neurocognitive foundations is essential for identifying how core functions such as emotional and self-referential processing…