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Digital information can be encoded in the building-block sequence of macro-molecules, such as RNA and single-stranded DNA. Methods of "writing" and "reading" macromolecular strands are currently available, but they are slow and expensive.…

Emerging Technologies · Computer Science 2017-09-14 Masud Mansuripur , Pramod Khulbe

We propose a new file format named "H5MD" for storing molecular simulation data, such as trajectories of particle positions and velocities, along with thermodynamic observables that are monitored during the course of the simulation. H5MD…

Computational Physics · Physics 2014-05-23 Pierre de Buyl , Peter H. Colberg , Felix Höfling

Hashing techniques are in great demand for a wide range of real-world applications such as image retrieval and network compression. Nevertheless, existing approaches could hardly guarantee a satisfactory performance with the extremely…

Information Retrieval · Computer Science 2020-02-13 Yadan Luo , Zi Huang , Yang Li , Fumin Shen , Yang Yang , Peng Cui

The growing prevalence of data-intensive workloads, such as artificial intelligence (AI), machine learning (ML), high-performance computing (HPC), in-memory databases, and real-time analytics, has exposed limitations in conventional memory…

Molecular dynamics (MD) is an important research tool extensively applied in materials science. Running MD on a graphics processing unit (GPU) is an attractive new approach for accelerating MD simulations. Currently, GPU implementations of…

Computational Physics · Physics 2015-06-12 Qing Hou , Min Li , Yulu Zhou , Jiechao Cui , Zhenguo Cui , Jun Wang

To store information at extremely high-density and data-rate, we propose to adapt, integrate, and extend the techniques developed by chemists and molecular biologists for the purpose of manipulating biological and other macromolecules. In…

Emerging Technologies · Computer Science 2017-08-29 M. Mansuripur , P. K. Khulbe , S. M. Kuebler , J. W. Perry , M. S. Giridhar , J. Kevin Erwin , Kibyung Seong , Seth Marder , N. Peyghambarian

Byte-addressable persistent memory (PM) brings hash tables the potential of low latency, cheap persistence and instant recovery. The recent advent of Intel Optane DC Persistent Memory Modules (DCPMM) further accelerates this trend. Many new…

Databases · Computer Science 2020-10-30 Baotong Lu , Xiangpeng Hao , Tianzheng Wang , Eric Lo

According to Moore law, the silicon semiconductor transistor based information system is facing its physical limitations due to fluctuations of random charge and leakage current. Molecular electronics is becoming more and more attractive…

Materials Science · Physics 2009-04-29 J. C. Li

The demand for high-density storage is urgent in the current era of data explosion. Recently, several single-molecule (-atom) magnets/ferroelectrics have been reported to be promising candidates for high-density storage. As another…

Materials Science · Physics 2023-11-02 Yali Yang , Liangliang Hong , Laurent Bellaiche , Hongjun Xiang

CXL (Compute Express Link) enables multiple hosts to share byte-addressable memory with hardware cache coherence, but no existing filesystem exploits this for lock-free multi-host coordination. We present DaxFS, a Linux filesystem for CXL…

Operating Systems · Computer Science 2026-04-03 Cong Wang , Yiwei Yang , Yusheng Zheng

We experimentally demonstrate an angularly-multiplexed holographic memory capable of intrinsic generation, storage and retrieval of multiple photons, based on off-resonant Raman interaction in warm rubidium-87 vapors. The memory capacity of…

Quantum Physics · Physics 2017-02-10 Radosław Chrapkiewicz , Michał Dąbrowski , Wojciech Wasilewski

Recent rapid strides in memory safety tools and hardware have improved software quality and security. While coarse-grained memory safety has improved, achieving memory safety at the granularity of individual objects remains a challenge due…

Cryptography and Security · Computer Science 2019-06-11 Hiroshi Sasaki , Miguel A. Arroyo , M. Tarek Ibn Ziad , Koustubha Bhat , Kanad Sinha , Simha Sethumadhavan

Large persistent memories such as NVDIMM have been perceived as a disruptive memory technology, because they can maintain the state of a system even after a power failure and allow the system to recover quickly. However, overheads incurred…

Hardware Architecture · Computer Science 2021-06-29 Jie Zhang , Miryeong Kwon , Donghyun Gouk , Sungjoon Koh , Nam Sung Kim , Mahmut Taylan Kandemir , Myoungsoo Jung

In this thesis, we describe a new, practical approach to integrating hardware-based data compression within the memory hierarchy, including on-chip caches, main memory, and both on-chip and off-chip interconnects. This new approach is fast,…

Hardware Architecture · Computer Science 2016-09-08 Gennady Pekhimenko

Modern model hubs, such as Hugging Face, store tens of petabytes of LLMs, with fine-tuned variants vastly outnumbering base models and dominating storage consumption. Existing storage reduction techniques -- such as deduplication and…

Databases · Computer Science 2025-11-11 Zirui Wang , Tingfeng Lan , Zhaoyuan Su , Juncheng Yang , Yue Cheng

As storage systems grow in size, device failures happen more frequently than ever before. Given the commodity nature of hard drives employed, a storage system needs to tolerate a certain number of disk failures while maintaining data…

Information Theory · Computer Science 2014-05-20 Yan Wang , Xunrui Yin , Xin Wang

The accelerating growth of global data generation demands data storage platforms that offer high capacity, long lifespan, and low energy consumption beyond the limits of electronic memory technologies. Optical storage provides an attractive…

Privacy-preserving computation techniques like homomorphic encryption (HE) and secure multi-party computation (SMPC) enhance data security by enabling processing on encrypted data. However, the significant computational and CPU-DRAM data…

Cryptography and Security · Computer Science 2024-09-26 Mpoki Mwaisela

Von Neumann architecture based computers isolate/physically separate computation and storage units i.e. data is shuttled between computation unit (processor) and memory unit to realize logic/ arithmetic and storage functions. This…

Emerging Technologies · Computer Science 2020-02-17 Sandeep Kaur Kingra , Vivek Parmar , Che-Chia Chang , Boris Hudec , Tuo-Hung Hou , Manan Suri

Deep learning hardware designs have been bottlenecked by conventional memories such as SRAM due to density, leakage and parallel computing challenges. Resistive devices can address the density and volatility issues, but have been limited by…

Emerging Technologies · Computer Science 2020-10-28 Shihui Yin , Xiaoyu Sun , Shimeng Yu , Jae-sun Seo
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