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The feedback-based algorithm for quantum optimization (FALQON) has recently been proposed to solve quadratic unconstrained binary optimization problems. This paper efficiently generalizes FALQON to tackle quadratic constrained binary…

Quantum Physics · Physics 2025-04-15 Salahuddin Abdul Rahman , Özkan Karabacak , Rafal Wisniewski

The Quantum Approximate Optimization Algorithm (QAOA) is among leading candidates for achieving quantum advantage on near-term processors. While typically implemented with a transverse-field mixer (XM-QAOA), the Grover-mixer variant…

Quantum Physics · Physics 2026-01-01 Evgeniy O. Kiktenko , Elizaveta V. Krendeleva , Aleksey K. Fedorov

Many real-time systems require the optimization of discrete variables. Black-box optimization (BBO) algorithms and multi-armed bandit (MAB) algorithms perform optimization by repeatedly taking actions and observing the corresponding instant…

Artificial Intelligence · Computer Science 2025-06-23 Tomoya Kashimata , Yohei Hamakawa , Masaya Yamasaki , Kosuke Tatsumura

Optimizing Reconfigurable Intelligent Surfaces (RIS) is a high-dimensional combinatorial challenge. Current quantum algorithms often simplify this problem by ignoring physical constraints like mutual coupling, which significantly degrades…

Computational Engineering, Finance, and Science · Computer Science 2026-05-08 Marco Pasquale , Erik M. Åsgrim , Stefano Markidis , Oscar Quevedo-Teruel

A wide spectrum of design and decision problems, including parameter tuning, A/B testing and drug design, intrinsically are instances of black-box optimization. Bayesian optimization (BO) is a powerful tool that models and optimizes such…

Machine Learning · Computer Science 2023-02-14 Tianyi Bai , Yang Li , Yu Shen , Xinyi Zhang , Wentao Zhang , Bin Cui

Vector Quantization (VQ) is a widely used technique in machine learning and data compression, valued for its simplicity and interpretability. Among hard VQ methods, $k$-medoids clustering and Kernel Density Estimation (KDE) approaches…

Machine Learning · Computer Science 2025-09-08 Thore Gerlach , Sascha Mücke , Christian Bauckhage

We consider the problem of black-box function optimization over the boolean hypercube. Despite the vast literature on black-box function optimization over continuous domains, not much attention has been paid to learning models for…

Operation management of nuclear power plants consists of several computationally hard problems. Searching for an in-core fuel loading pattern is among them. The main challenge of this combinatorial optimization problem is the exponential…

Solving combinatorial optimization problems on current noisy quantum devices is currently being advocated for (and restricted to) binary polynomial optimization with equality constraints via quantum heuristic approaches. This is achieved…

Quantum Physics · Physics 2021-02-04 Claudio Gambella , Andrea Simonetto

Feature selection is a machine learning technique for identifying relevant variables in classification and regression models. In single-cell RNA sequencing (scRNA-seq) data analysis, feature selection is used to identify relevant genes that…

Genomics · Quantitative Biology 2025-12-02 Selim Romero , Shreyan Gupta , Victoria Gatlin , Robert S. Chapkin , James J. Cai

We propose a novel method for gradient-based optimization of black-box simulators using differentiable local surrogate models. In fields such as physics and engineering, many processes are modeled with non-differentiable simulators with…

Machine Learning · Computer Science 2020-09-30 Sergey Shirobokov , Vladislav Belavin , Michael Kagan , Andrey Ustyuzhanin , Atılım Güneş Baydin

This paper proposes a novel matrix quantization method, Binary Quadratic Quantization (BQQ). In contrast to conventional first-order quantization approaches, such as uniform quantization and binary coding quantization, that approximate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Kyo Kuroki , Yasuyuki Okoshi , Thiem Van Chu , Kazushi Kawamura , Masato Motomura

In this paper, we study the computational complexity of the quadratic unconstrained binary optimization (QUBO) problem under the functional problem FP^NP categorization. We focus on four sub-classes: (1) When all coefficients are integers…

Computational Complexity · Computer Science 2022-02-21 Hirotoshi Yasuoka

Quantum-inspired optimization (QIO) algorithms are computational techniques that emulate certain quantum mechanical effects on a classical hardware to tackle a class of optimization tasks. QIO methods have so far been employed to solve…

Quantum Physics · Physics 2022-12-07 Rathi Munukur , Bhaskar Roy Bardhan , Devesh Upadhyay , Joydip Ghosh

Quantum annealers offer a promising hardware platform for solving combinatorial optimization problems, especially those formulated as Quadratic Unconstrained Binary Optimization (QUBO). In this work, we propose PDQUBO (Performance-Driven…

Information Retrieval · Computer Science 2026-05-01 Jiayang Niu , Jie Li , Ke Deng , Mark Sanderson , Nicola Ferro , Yongli Ren

As a dedicated quantum device, Ising machines could solve large-scale binary optimization problems in milliseconds. There is emerging interest in utilizing Ising machines to train feedforward neural networks due to the prosperity of…

Machine Learning · Computer Science 2023-11-08 Xujie Song , Tong Liu , Shengbo Eben Li , Jingliang Duan , Wenxuan Wang , Keqiang Li

Bilevel optimization is characterized by a two-level optimization structure, where the upper-level problem is constrained by optimal lower-level solutions, and such structures are prevalent in real-world problems. The constraint by optimal…

Machine Learning · Computer Science 2025-05-29 Ruth Wan Theng Chew , Quoc Phong Nguyen , Bryan Kian Hsiang Low

Inverse Optimization (IO) is a framework for learning the unknown objective function of an expert decision-maker from a past dataset. In this paper, we extend the hypothesis class of IO objective functions to a reproducing kernel Hilbert…

Machine Learning · Computer Science 2024-11-01 Youyuan Long , Tolga Ok , Pedro Zattoni Scroccaro , Peyman Mohajerin Esfahani

Bayesian Optimization (BO) is a method for globally optimizing black-box functions. While BO has been successfully applied to many scenarios, developing effective BO algorithms that scale to functions with high-dimensional domains is still…

Machine Learning · Computer Science 2024-02-13 Yihang Shen , Carl Kingsford

Combinatorial optimization problems are typically formulated using Quadratic Unconstrained Binary Optimization (QUBO), where constraints are enforced through penalty terms that introduce auxiliary variables and rapidly increase Hamiltonian…

Quantum Physics · Physics 2026-02-10 Shashank Sanjay Bhat , Peiyong Wang , Joseph West , Udaya Parampalli