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Agent-based models have been employed to describe numerous processes in immunology. Simulations based on these types of models have been used to enhance our understanding of immunology and disease pathology. We review various agent-based…

Cell Behavior · Quantitative Biology 2017-12-05 Amy L. Bauer , Catherine A. A. Beauchemin , Alan S. Perelson

Recent interest in human-AI interactions in agent-based modeling and simulation (ABMS) has grown rapidly due to the widespread utilization of large language models (LLMs). ABMS is an intelligent approach that simulates autonomous agents'…

Human-Computer Interaction · Computer Science 2025-06-18 Ziyue Lin , Siqi Shen , Zichen Cheng , Cheok Lam Lai , Siming Chen

Foundation models have reshaped AI by unifying fragmented architectures into scalable backbones with multimodal reasoning and contextual adaptation. In parallel, the long-standing notion of AI agents, defined by the sensing-decision-action…

Machine Learning · Computer Science 2025-10-02 Sicong Liu , Weiye Wu , Xiangrui Xu , Teng Li , Bowen Pang , Bin Guo , Zhiwen Yu

This article proposes a methodology to model and simulate complex systems, based on IRM4MLS, a generic agent-based meta-model able to deal with multi-level systems. This methodology permits the engineering of dynamic multi-level agent-based…

Multiagent Systems · Computer Science 2013-11-21 Jean-Baptiste Soyez , Gildas Morvan , Daniel Dupont , Rochdi Merzouki

How should an agent decide when and how to plan? A dominant approach builds agents as reactive policies with adaptive computation (e.g., chain-of-thought), trained end-to-end expecting planning to emerge implicitly. Without control over the…

Artificial Intelligence · Computer Science 2026-05-22 Mingkai Deng , Jinyu Hou , Lara Sá Neves , Varad Pimpalkhute , Taylor W. Killian , Zhengzhong Liu , Eric P. Xing

Ramp merging is one of the bottlenecks in traffic systems, which commonly cause traffic congestion, accidents, and severe carbon emissions. In order to address this essential issue and enhance the safety and efficiency of connected and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-25 Senkang Hu , Zhengru Fang , Zihan Fang , Yiqin Deng , Xianhao Chen , Yuguang Fang , Sam Kwong

Autonomous agents driven by Large Language Models (LLMs) offer enormous potential for automation. Early proof of this technology can be found in various demonstrations of agents solving complex tasks, interacting with external systems to…

In social sciences, researchers often face challenges when conducting large-scale experiments, particularly due to the simulations' complexity and the lack of technical expertise required to develop such frameworks. Agent-Based Modeling…

Multi-agent reinforcement learning is difficult to be applied in practice, which is partially due to the gap between the simulated and real-world scenarios. One reason for the gap is that the simulated systems always assume that the agents…

Machine Learning · Computer Science 2022-03-17 Jian Zhao , Youpeng Zhao , Weixun Wang , Mingyu Yang , Xunhan Hu , Wengang Zhou , Jianye Hao , Houqiang Li

In a multi-agent system, agents share their local observations to gain global situational awareness for decision making and collaboration using a message passing system. When to send a message, how to encode a message, and how to leverage…

Multiagent Systems · Computer Science 2024-07-01 Qinwei Huang , Chen Luo , Alex B. Wu , Simon Khan , Hai Li , Qinru Qiu

Large Language Model based multi-agent systems (MAS) excel at collaborative problem solving but remain brittle to cascading errors: a single faulty step can propagate across agents and disrupt the trajectory. In this paper, we present MASC,…

With recent breakthroughs in large language models (LLMs) for reasoning, planning, and complex task generation, artificial intelligence systems are transitioning from isolated single-agent architectures to multi-agent systems with…

Artificial Intelligence · Computer Science 2026-02-17 Linlin Wang , Tianqing Zhu , Laiqiao Qin , Longxiang Gao , Wanlei Zhou

While multi-agent systems (MAS) have demonstrated superior performance over single-agent approaches in complex reasoning tasks, they often suffer from significant computational inefficiencies. Existing frameworks typically deploy large…

Artificial Intelligence · Computer Science 2026-01-27 Jingbo Wang , Sendong Zhao , Jiatong Liu , Haochun Wang , Wanting Li , Bing Qin , Ting Liu

The fast development of Artificial Intelligence (AI) agents provides a promising way for the realization of intelligent and customized wireless networks. In this paper, we propose a Wireless Multi-Agent System (WMAS), which can provide…

Multiagent Systems · Computer Science 2025-08-04 Jingchen Peng , Dingli Yuan , Boxiang Ren , Jie Fan , Hao Wu , Lu Yang

A self-learning adaptive system (SLAS) uses machine learning to enable and enhance its adaptability. Such systems are expected to perform well in dynamic situations. For learning high-performance adaptation policy, some assumptions must be…

Software Engineering · Computer Science 2021-05-12 Mingyue Zhang , Jialong Li , Haiyan Zhao , Kenji Tei , Shinichi Honiden , Zhi Jin

Interpretability is a pressing issue for decision systems. Many post hoc methods have been proposed to explain the predictions of a single machine learning model. However, business processes and decision systems are rarely centered around a…

Machine Learning · Computer Science 2023-03-22 Gianluigi Lopardo , Damien Garreau , Frederic Precioso , Greger Ottosson

With the continuous and vast increase in the amount of data in our digital world, it has been acknowledged that the number of knowledgeable data scientists can not scale to address these challenges. Thus, there was a crucial need for…

Machine Learning · Computer Science 2019-06-12 Radwa Elshawi , Mohamed Maher , Sherif Sakr

Advances in Agent Oriented Software Engineering have focused on the provision of frameworks and toolkits to aid in the creation of Multi Agent Systems (MASs). However, despite the need to address the inherent complexity of such systems,…

Multiagent Systems · Computer Science 2015-08-12 Dinh Doan Van Bien , David Lillis , Rem W. Collier

Symbiotic Autonomous Systems (SAS) are advanced intelligent and cognitive systems exhibiting autonomous collective intelligence enabled by coherent symbiosis of human-machine interactions in hybrid societies. Basic research in the emerging…

The advent of Large Language Models (LLMs) has significantly transformed tasks across Software Engineering. In the context of Business Process Management, LLMs are now being explored as tools to derive process models directly from textual…

Software Engineering · Computer Science 2026-05-01 Pedro-Aarón Hernández-Ávalos , Luciano García-Bañuelos