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Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

Though performed almost effortlessly by humans, segmenting 2D gray-scale or color images into respective regions of interest (e.g.~background, objects, or portions of objects) constitutes one of the greatest challenges in science and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Alexandre Benatti , Luciano da F. Costa

Semi-supervised learning has attracted much attention in medical image segmentation due to challenges in acquiring pixel-wise image annotations, which is a crucial step for building high-performance deep learning methods. Most existing…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Shuailin Li , Chuyu Zhang , Xuming He

Although deep learning (DL) shows powerful potential in cell segmentation tasks, it suffers from poor generalization as DL-based methods originally simplified cell segmentation in detecting cell membrane boundary, lacking prominent cellular…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Fang Hu , Xuexue Sun , Ke Qing , Fenxi Xiao , Zhi Wang , Xiaolu Fan

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

Automated and semi-automated techniques in biomedical electron microscopy (EM) enable the acquisition of large datasets at a high rate. Segmentation methods are therefore essential to analyze and interpret these large volumes of data, which…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Anusha Aswath , Ahmad Alsahaf , Ben N. G. Giepmans , George Azzopardi

Computer-aided design (CAD) tools are increasingly popular in modern dental practice, particularly for treatment planning or comprehensive prognosis evaluation. In particular, the 2D panoramic X-ray image efficiently detects invisible…

Morphology of mitochondria plays critical roles in mediating their physiological functions. Accurate segmentation of mitochondria from 3D electron microscopy (EM) images is essential to quantitative characterization of their morphology at…

Computer Vision and Pattern Recognition · Computer Science 2022-06-16 Yunpeng Xiao , Youpeng Zhao , Ge Yang

Supervised machine learning provides state-of-the-art solutions to a wide range of computer vision problems. However, the need for copious labelled training data limits the capabilities of these algorithms in scenarios where such input is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-02 András Kalapos , Bálint Gyires-Tóth

Medical image segmentation has advanced rapidly over the past two decades, largely driven by deep learning, which has enabled accurate and efficient delineation of cells, tissues, organs, and pathologies across diverse imaging modalities.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Guoping Xu , Jayaram K. Udupa , Jax Luo , Songlin Zhao , Yajun Yu , Scott B. Raymond , Hao Peng , Lipeng Ning , Yogesh Rathi , Wei Liu , You Zhang

3D deep learning is a growing field of interest due to the vast amount of information stored in 3D formats. Triangular meshes are an efficient representation for irregular, non-uniform 3D objects. However, meshes are often challenging to…

Computer Vision and Pattern Recognition · Computer Science 2022-12-23 Ayaan Haque , Hankyu Moon , Heng Hao , Sima Didari , Jae Oh Woo , Patrick Bangert

3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Hao Zheng , Yizhe Zhang , Lin Yang , Peixian Liang , Zhuo Zhao , Chaoli Wang , Danny Z. Chen

Supervised learning demands large amounts of precisely annotated data to achieve promising results. Such data curation is labor-intensive and imposes significant overhead regarding time and costs. Self-supervised learning (SSL) partially…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Thangarajah Akilan , Nusrat Jahan , Wandong Zhang

Advances in fluorescence microscopy enable acquisition of 3D image volumes with better image quality and deeper penetration into tissue. Segmentation is a required step to characterize and analyze biological structures in the images and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Chichen Fu , Soonam Lee , David Joon Ho , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

Self-supervised learning methods have witnessed a recent surge of interest after proving successful in multiple application fields. In this work, we leverage these techniques, and we propose 3D versions for five different self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Aiham Taleb , Winfried Loetzsch , Noel Danz , Julius Severin , Thomas Gaertner , Benjamin Bergner , Christoph Lippert

Automatic liver segmentation from CT volumes is a crucial prerequisite yet challenging task for computer-aided hepatic disease diagnosis and treatment. In this paper, we present a novel 3D deeply supervised network (3D DSN) to address this…

Computer Vision and Pattern Recognition · Computer Science 2016-07-05 Qi Dou , Hao Chen , Yueming Jin , Lequan Yu , Jing Qin , Pheng-Ann Heng

Medical image segmentation has been significantly advanced by deep learning (DL) techniques, though the data scarcity inherent in medical applications poses a great challenge to DL-based segmentation methods. Self-supervised learning offers…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Binyan Hu , A. K. Qin

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in…

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio
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