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The absence of adequately sufficient expert-level tumor annotations hinders the effectiveness of supervised learning based opportunistic cancer screening on medical imaging. Clinical reports (that are rich in descriptive textual details)…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Guangyu Guo , Jiawen Yao , Yingda Xia , Tony C. W. Mok , Zhilin Zheng , Junwei Han , Le Lu , Dingwen Zhang , Jian Zhou , Ling Zhang

Annotated datasets are an essential ingredient to train, evaluate, compare and productionalize supervised machine learning models. It is therefore imperative that annotations are of high quality. For their creation, good quality management…

Machine Learning · Computer Science 2024-05-30 Jan-Christoph Klie , Juan Haladjian , Marc Kirchner , Rahul Nair

Diagnostic errors in healthcare persist as a critical challenge, with increasing numbers of patients turning to online resources for health information. While AI-powered healthcare chatbots show promise, there exists no standardized and…

Artificial Intelligence · Computer Science 2024-12-18 Deep Bhatt , Surya Ayyagari , Anuruddh Mishra

Recent years showed a strong increase in biomedical sciences and an inherent increase in publication volume. Extraction of specific information from these sources requires highly sophisticated text mining and information extraction tools.…

Computation and Language · Computer Science 2020-04-09 Johannes Kirschnick , Philippe Thomas , Roland Roller , Leonhard Hennig

Multimodal large language models (MLLMs) have made significant strides, yet they face challenges in the medical domain due to limited specialized knowledge. While recent medical MLLMs demonstrate strong performance in lab settings, they…

Computation and Language · Computer Science 2024-10-22 Junda Wang , Yujan Ting , Eric Z. Chen , Hieu Tran , Hong Yu , Weijing Huang , Terrence Chen

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Manual annotation of volumetric medical images, such as magnetic resonance imaging (MRI) and computed tomography (CT), is a labor-intensive and time-consuming process. Recent advancements in foundation models for video object segmentation,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Yuwen Chen , Zafer Yildiz , Qihang Li , Yaqian Chen , Haoyu Dong , Hanxue Gu , Nicholas Konz , Maciej A. Mazurowski

Statistical Shape Models (SSMs) excel at identifying population level anatomical variations, which is at the core of various clinical and biomedical applications, including morphology-based diagnostics and surgical planning. However, the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Asma Khan , Tushar Kataria , Janmesh Ukey , Shireen Y. Elhabian

Accurate segmentation and classification of brain tumors from Magnetic Resonance Imaging (MRI) remain key challenges in medical image analysis, primarily due to the lack of high-quality, balanced, and diverse datasets with expert…

Image and Video Processing · Electrical Eng. & Systems 2026-01-29 Amirreza Fateh , Yasin Rezvani , Sara Moayedi , Sadjad Rezvani , Fatemeh Fateh , Mansoor Fateh , Vahid Abolghasemi

Large language models (LLMs) are increasingly positioned as scalable tools for annotating educational data, including classroom discourse, interaction logs, and qualitative learning artifacts. Their ability to rapidly summarize…

Artificial Intelligence · Computer Science 2026-03-17 Bakhtawar Ahtisham , Kirk Vanacore , Rene F. Kizilcec

Expectation-Maximization (EM) algorithm is a widely used iterative algorithm for computing maximum likelihood estimate when dealing with Gaussian Mixture Model (GMM). When the sample size is smaller than the data dimension, this could lead…

Machine Learning · Statistics 2023-07-06 Pierre Houdouin , Matthieu Jonkcheere , Frederic Pascal

Significant advances are being made in speech emotion recognition (SER) using deep learning models. Nonetheless, training SER systems remains challenging, requiring both time and costly resources. Like many other machine learning tasks,…

Sound · Computer Science 2023-09-18 Tiantian Feng , Shrikanth Narayanan

Two of the most common tasks in medical imaging are classification and segmentation. Either task requires labeled data annotated by experts, which is scarce and expensive to collect. Annotating data for segmentation is generally considered…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Ozan Ciga , Anne L. Martel

Developing accurate clinical prediction models is often bottlenecked by the difficulty of deriving meaningful structured features from unstructured EHR notes, a process that traditionally requires manual, unscalable clinical abstraction. In…

Computer-assisted surgery research requires large, deeply annotated video datasets that capture clinical and technical variability. Existing cataract surgery resources lack the diversity and annotation depth required to train generalizable…

Fine-tuning language models~(LMs) on human-generated data remains a prevalent practice. However, the performance of such models is often limited by the quantity and diversity of high-quality human data. In this paper, we explore whether we…

Expectation-Maximization (EM) algorithm is a widely used iterative algorithm for computing (local) maximum likelihood estimate (MLE). It can be used in an extensive range of problems, including the clustering of data based on the Gaussian…

Machine Learning · Statistics 2023-03-28 Pierre Houdouin , Esa Ollila , Frederic Pascal

As Large Language Models (LLMs) gain wider adoption, ensuring their reliable handling of Personally Identifiable Information (PII) across diverse regulatory contexts has become essential. This work introduces a scalable multilingual data…

Computation and Language · Computer Science 2025-10-13 Bharti Meena , Joanna Skubisz , Harshit Rajgarhia , Nand Dave , Kiran Ganesh , Shivali Dalmia , Abhishek Mukherji , Vasudevan Sundarababu

This study compares two statistical approaches to image reconstruction in single-photon emission computed tomography (SPECT). We evaluated the widely used Ordered Subset Expectation Maximization (OSEM) algorithm and the newer Maximum a…

Numerical Analysis · Mathematics 2025-12-22 A. V. Nesterova , N. V. Denisova

Despite continuous advancements in cancer treatment, brain metastatic disease remains a significant complication of primary cancer and is associated with an unfavorable prognosis. One approach for improving diagnosis, management, and…

Other Quantitative Biology · Quantitative Biology 2025-07-11 Nazanin Maleki , Raisa Amiruddin , Ahmed W. Moawad , Nikolay Yordanov , Athanasios Gkampenis , Pascal Fehringer , Fabian Umeh , Crystal Chukwurah , Fatima Memon , Bojan Petrovic , Justin Cramer , Mark Krycia , Elizabeth B. Shrickel , Ichiro Ikuta , Gerard Thompson , Lorenna Vidal , Vilma Kosovic , Adam E. Goldman-Yassen , Virginia Hill , Tiffany So , Sedra Mhana , Albara Alotaibi , Nathan Page , Prisha Bhatia , Melisa S. Guelen , Yasaman Sharifi , Marko Jakovljevic , Salma Abosabie , Sara Abosabie , Mohanad Ghonim , Mohamed Ghonim , Amirreza Manteghinejad , Anastasia Janas , Kiril Krantchev , Maruf Adewole , Jake Albrecht , Udunna Anazodo , Sanjay Aneja , Syed Muhammad Anwar , Timothy Bergquist , Veronica Chiang , Verena Chung , Gian Marco Conte , Farouk Dako , James Eddy , Ivan Ezhov , Nastaran Khalili , Keyvan Farahani , Juan Eugenio Iglesias , Zhifan Jiang , Elaine Johanson , Anahita Fathi Kazerooni , Florian Kofler , Dominic LaBella , Koen Van Leemput , Hongwei Bran Li , Marius George Linguraru , Xinyang Liu , Zeke Meier , Bjoern H Menze , Harrison Moy , Klara Osenberg , Marie Piraud , Zachary Reitman , Russell Takeshi Shinohara , Chunhao Wang , Benedikt Wiestler , Walter Wiggins , Umber Shafique , Klara Willms , Arman Avesta , Khaled Bousabarah , Satrajit Chakrabarty , Nicolo Gennaro , Wolfgang Holler , Manpreet Kaur , Pamela LaMontagne , MingDe Lin , Jan Lost , Daniel S. Marcus , Ryan Maresca , Sarah Merkaj , Gabriel Cassinelli Pedersen , Marc von Reppert , Aristeidis Sotiras , Oleg Teytelboym , Niklas Tillmans , Malte Westerhoff , Ayda Youssef , Devon Godfrey , Scott Floyd , Andreas Rauschecker , Javier Villanueva-Meyer , Irada Pflüger , Jaeyoung Cho , Martin Bendszus , Gianluca Brugnara , Gloria J. Guzman Perez-Carillo , Derek R. Johnson , Anthony Kam , Benjamin Yin Ming Kwan , Lillian Lai , Neil U. Lall , Satya Narayana Patro , Lei Wu , Anu Bansal , Frederik Barkhof , Cristina Besada , Sammy Chu , Jason Druzgal , Alexandru Dusoi , Luciano Farage , Fabricio Feltrin , Amy Fong , Steve H. Fung , R. Ian Gray , Michael Iv , Alida A. Postma , Amit Mahajan , David Joyner , Chase Krumpelman , Laurent Letourneau-Guillon , Christie M. Lincoln , Mate E. Maros , Elka Miller , Fanny Morón , Esther A. Nimchinsky , Ozkan Ozsarlak , Uresh Patel , Saurabh Rohatgi , Atin Saha , Anousheh Sayah , Eric D. Schwartz , Robert Shih , Mark S. Shiroishi , Juan E. Small , Manoj Tanwar , Jewels Valerie , Brent D. Weinberg , Matthew L. White , Robert Young , Vahe M. Zohrabian , Aynur Azizova , Melanie Maria Theresa Brüßeler , Abdullah Okar , Luca Pasquini , Yasaman Sharifi , Gagandeep Singh , Nico Sollmann , Theodora Soumala , Mahsa Taherzadeh , Philipp Vollmuth , Martha Foltyn-Dumitru , Ajay Malhotra , Francesco Dellepiane , Víctor M. Pérez-García , Hesham Elhalawani , Maria Correia de Verdier , Sanaria Al Rubaiey , Rui Duarte Armindo , Kholod Ashraf , Moamen M. Asla , Mohamed Badawy , Jeroen Bisschop , Nima Broomand Lomer , Jan Bukatz , Jim Chen , Petra Cimflova , Felix Corr , Alexis Crawley , Lisa Deptula , Tasneem Elakhdar , Islam H. Shawali , Shahriar Faghani , Alexandra Frick , Vaibhav Gulati , Muhammad Ammar Haider , Fátima Hierro , Rasmus Holmboe Dahl , Sarah Maria Jacobs , Kuang-chun Jim Hsieh , Sedat G. Kandemirli , Katharina Kersting , Laura Kida , Sofia Kollia , Ioannis Koukoulithras , Xiao Li , Ahmed Abouelatta , Aya Mansour , Ruxandra-Catrinel Maria-Zamfirescu , Marcela Marsiglia , Yohana Sarahi Mateo-Camacho , Mark McArthur , Olivia McDonnel , Maire McHugh , Mana Moassefi , Samah Mostafa Morsi , Alexander Munteanu , Khanak K. Nandolia , Syed Raza Naqvi , Yalda Nikanpour , Mostafa Alnoury , Abdullah Mohamed Aly Nouh , Francesca Pappafava , Markand D. Patel , Samantha Petrucci , Eric Rawie , Scott Raymond , Borna Roohani , Sadeq Sabouhi , Laura M. Sanchez Garcia , Zoe Shaked , Pokhraj P. Suthar , Talissa Altes , Edvin Isufi , Yaseen Dhemesh , Jaime Gass , Jonathan Thacker , Abdul Rahman Tarabishy , Benjamin Turner , Sebastiano Vacca , George K. Vilanilam , Daniel Warren , David Weiss , Fikadu Worede , Sara Yousry , Wondwossen Lerebo , Alejandro Aristizabal , Alexandros Karargyris , Hasan Kassem , Sarthak Pati , Micah Sheller , Katherine E. Link , Evan Calabrese , Nourel Hoda Tahon , Ayman Nada , Jeffrey D. Rudie , Janet Reid , Kassa Darge , Aly H. Abayazeed , Philipp Lohmann , Yuri S. Velichko , Spyridon Bakas , Mariam Aboian