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Large language models (LLMs) have demonstrated exceptional performance across various applications, but their conversational abilities decline sharply as model size decreases, presenting a barrier to their deployment in resource-constrained…

Machine Learning · Computer Science 2025-06-23 Zhengze Zhang , Shiqi Wang , Yiqun Shen , Simin Guo , Dahua Lin , Xiaoliang Wang , Nguyen Cam-Tu , Fei Tan

We present a multi-objective binder design paradigm based on instruction fine-tuning and direct preference optimization (DPO) of autoregressive protein language models (pLMs). Multiple design objectives are encoded in the language model…

Biological Physics · Physics 2024-03-08 Pouria Mistani , Venkatesh Mysore

Normative theories allow one to elicit key parts of a ML algorithm from first principles, which is crucial at a time of championed scrutiny for ML work. Direct Preference Optimization (DPO) cleverly bypasses reward modeling by making an…

Machine Learning · Computer Science 2026-02-05 Wenxuan Zhou , Shujian Zhang , Brice Magdalou , John Lambert , Ehsan Amid , Richard Nock , Andrew Hard

As Large Language Models (LLMs) demonstrate remarkable capabilities learned from vast corpora, concerns regarding data privacy and safety are receiving increasing attention. LLM unlearning, which aims to remove the influence of specific…

Machine Learning · Computer Science 2025-10-07 Kai Qin , Jiaqi Wu , Jianxiang He , Haoyuan Sun , Yifei Zhao , Bin Liang , Yongzhe Chang , Tiantian Zhang , Houde Liu

Reinforcement learning from human feedback (RLHF) has been extensively employed to align large language models with user intent. However, proximal policy optimization (PPO) based RLHF is occasionally unstable requiring significant…

Computation and Language · Computer Science 2024-04-02 Saeed Khaki , JinJin Li , Lan Ma , Liu Yang , Prathap Ramachandra

Direct Preference Optimization (DPO) is successful for alignment in LLMs but still faces challenges in text-to-image generation. Existing studies are confined to denoising diffusion models while overlooking flow-matching, and suffer from an…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Kesong Li , Yixuan Xu , Kuo-kun Tseng , Weiyi Lu , Kan Liu , Tao Lan

Direct Preference Optimization (DPO) has been proposed as an effective and efficient alternative to reinforcement learning from human feedback (RLHF). In this paper, we propose a novel and enhanced version of DPO based on curriculum…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Florinel-Alin Croitoru , Vlad Hondru , Radu Tudor Ionescu , Nicu Sebe , Mubarak Shah

While Retrieval-Augmented Generation (RAG) has exhibited promise in utilizing external knowledge, its generation process heavily depends on the quality and accuracy of the retrieved context. Large language models (LLMs) struggle to evaluate…

Computation and Language · Computer Science 2025-10-13 Shi-Qi Yan , Quan Liu , Zhen-Hua Ling

Recent advancements in text-to-speech (TTS) have shown that language model (LM)-based systems offer competitive performance to their counterparts. Further optimization can be achieved through preference alignment algorithms, which adjust…

Computation and Language · Computer Science 2024-09-20 Jinchuan Tian , Chunlei Zhang , Jiatong Shi , Hao Zhang , Jianwei Yu , Shinji Watanabe , Dong Yu

Recent advancements in large language model alignment leverage token-level supervisions to perform fine-grained preference optimization. However, existing token-level alignment methods either optimize on all available tokens, which can be…

Computation and Language · Computer Science 2025-11-07 Kailai Yang , Zhiwei Liu , Qianqian Xie , Jimin Huang , Erxue Min , Sophia Ananiadou

Direct Preference Optimization (DPO) aligns text-to-image (T2I) generation models with human preferences using pairwise preference data. Although substantial resources are expended in collecting and labeling datasets, a critical aspect is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Yunhong Lu , Qichao Wang , Hengyuan Cao , Xiaoyin Xu , Min Zhang

Large Language Models (LLMs) have demonstrated remarkable capabilities through pretraining and alignment. However, superior short-context LLMs may underperform in long-context scenarios due to insufficient long-context alignment. This…

Computation and Language · Computer Science 2025-03-04 Guanzheng Chen , Xin Li , Michael Qizhe Shieh , Lidong Bing

Direct Preference Optimization (DPO) has emerged as a popular alternative to Reinforcement Learning from Human Feedback (RLHF), offering theoretical equivalence with simpler implementation. We prove this equivalence is conditional rather…

Artificial Intelligence · Computer Science 2026-05-21 Zhiqin Yang , Yonggang Zhang , Wei Xue , Dong Fang , Bo Han , Yike Guo

Direct Preference Optimization (DPO) improves the alignment of large language models (LLMs) with human values by training directly on human preference datasets, eliminating the need for reward models. However, due to the presence of…

Artificial Intelligence · Computer Science 2024-06-11 Biqing Qi , Pengfei Li , Fangyuan Li , Junqi Gao , Kaiyan Zhang , Bowen Zhou

Diffusion models have achieved remarkable progress in text-to-image generation, yet aligning them with human preference remains challenging due to the presence of multiple, sometimes conflicting, evaluation metrics (e.g., semantic…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Dipesh Tamboli , Souradip Chakraborty , Aditya Malusare , Biplab Banerjee , Amrit Singh Bedi , Vaneet Aggarwal

Large language models (LLMs) alignment aims to ensure that the behavior of LLMs meets human preferences. While collecting data from multiple fine-grained, aspect-specific preferences becomes more and more feasible, existing alignment…

Machine Learning · Computer Science 2026-03-03 Jia Zhang , Yao Liu , Chen-Xi Zhang , Yi Liu , Yi-Xuan Jin , Lan-Zhe Guo , Yu-Feng Li

Aligning Large Language Models (LLMs) with human feedback is crucial for their development. Existing preference optimization methods such as DPO and KTO, while improved based on Reinforcement Learning from Human Feedback (RLHF), are…

Computation and Language · Computer Science 2024-12-23 Shuo Xie , Fangzhi Zhu , Jiahui Wang , Lulu Wen , Wei Dai , Xiaowei Chen , Junxiong Zhu , Kai Zhou , Bo Zheng

Direct Preference Optimization (DPO) has been proposed as an effective and efficient alternative to reinforcement learning from human feedback (RLHF). However, neither RLHF nor DPO take into account the fact that learning certain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Florinel-Alin Croitoru , Vlad Hondru , Radu Tudor Ionescu , Nicu Sebe , Mubarak Shah

Aligning intelligent agents with human preferences and values is important. This paper examines two popular alignment methods: Direct Preference Optimization (DPO) and Reward-Model-Based Policy Optimization (RMB-PO). A variant of RMB-PO,…

Machine Learning · Computer Science 2024-02-27 Ziniu Li , Tian Xu , Yang Yu

Traditional preference tuning methods for LLMs/Visual Generative Models often rely solely on reward model labeling, which can be opaque, offer limited insights into the rationale behind preferences, and are prone to issues such as reward…

Machine Learning · Computer Science 2026-01-13 Hanyang Zhao , Haoxian Chen , Yucheng Guo , Genta Indra Winata , Tingting Ou , Ziyu Huang , David D. Yao , Wenpin Tang
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