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The dynamics of Boolean networks (the N-K model) with scale-free topology are studied here. The existence of a phase transition governed by the value of the scale-free exponent of the network is shown analytically by analyzing the overlap…

Disordered Systems and Neural Networks · Physics 2007-05-23 Maximino Aldana

Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…

Molecular Networks · Quantitative Biology 2019-12-06 Elijah Paul , Gleb Pogudin , William Qin , Reinhard Laubenbacher

Using Boolean networks as prototypical examples, the role of symmetry in the dynamics of heterogeneous complex systems is explored. We show that symmetry of the dynamics, especially in critical states, is a controlling feature that can be…

Statistical Mechanics · Physics 2015-06-19 Shabnam Hossein , Matthew D. Reichl , Kevin E. Bassler

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

Molecular Networks · Quantitative Biology 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

Continuous-time systems with switch-like behaviour occur in chemical kinetics, gene regulatory networks and neural networks. Networks with hard switching, as a limiting case of smooth sigmoidal switching, retain the richest possible range…

Dynamical Systems · Mathematics 2019-05-10 Roderick Edwards

In this paper we study the phase transitions of different types of Random Boolean networks. These differ in their updating scheme: synchronous, semi-synchronous, or asynchronous, and deterministic or non-deterministic. It has been shown…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Carlos Gershenson

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

We study expanding circle maps interacting in a heterogeneous random network. Heterogeneity means that some nodes in the network are massively connected, while the remaining nodes are only poorly connected. We provide a probabilistic…

Dynamical Systems · Mathematics 2013-08-27 Tiago Pereira , Sebastian van Strien , Jeroen S. W. Lamb

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Dynamical Systems · Mathematics 2015-02-26 Marco Villani , Davide Campioli , Chiara Damiani , Andrea Roli , Alessandro Filisetti , Roberto Serra

We analyse the equilibrium behaviour and non-equilibrium dynamics of sparse Boolean networks with self-interactions that evolve according to synchronous Glauber dynamics. Equilibrium analysis is achieved via a novel application of the…

Disordered Systems and Neural Networks · Physics 2022-10-19 Christian John Hurry , Alexander Mozeika , Alessia Annibale

Many natural systems are organized as networks, in which the nodes (be they cells, individuals or populations) interact in a time-dependent fashion. The dynamic behavior of these networks depends on how these nodes are connected, which can…

Neurons and Cognition · Quantitative Biology 2015-06-22 Anca Radulescu , Sergio Verduzco-Flores

Heteroclinic structures organize global features of dynamical systems. We analyze whether heteroclinic structures can arise in network dynamics with higher-order interactions which describe the nonlinear interactions between three or more…

Dynamical Systems · Mathematics 2024-02-27 Christian Bick , Sören von der Gracht

This paper aims at setting the keystone of a prospective theoretical study on the role of non-monotone interactions in biological regulation networks. Focusing on discrete models of these networks, namely, Boolean automata networks, we…

Discrete Mathematics · Computer Science 2011-12-01 Mathilde Noual , Damien Regnault , Sylvain Sené

The focus of this thesis is about statistical mechanics on heterogeneous random graphs, i.e. how this heterogeneity affects the cooperative behavior of model systems. It is not intended as a review on it, rather it is showed how this…

Statistical Mechanics · Physics 2010-10-27 Daniele De Martino

Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

Molecular Networks · Quantitative Biology 2023-02-06 Larry Bull

We propose a statistical mechanics approach to a coevolving spin system with an adaptive network of interactions. The dynamics of node states and network connections is driven by both spin configuration and network topology. We consider a…

Physics and Society · Physics 2018-10-03 Tomasz Raducha , Mateusz Wiliński , Tomasz Gubiec , H. Eugene Stanley

We analyse a model of fixed in-degree Random Boolean Networks in which the fraction of input-receiving nodes is controlled by a parameter gamma. We investigate analytically and numerically the dynamics of graphs under a parallel XOR…

Statistical Mechanics · Physics 2009-09-03 L. Ciandrini , C. Maffi , A. Motta , B. Bassetti , M. Cosentino Lagomarsino

The collective dynamics of interacting dynamical units on a network crucially depends on the properties of the network structure. Rather than considering large but finite graphs to capture the network, one often resorts to graph limits and…

Dynamical Systems · Mathematics 2024-08-06 Christian Bick , Davide Sclosa

Networks are a widely used and efficient paradigm to model real-world systems where basic units interact pairwise. Many body interactions are often at play, and cannot be modelled by resorting to binary exchanges. In this work, we consider…

Adaptation and Self-Organizing Systems · Physics 2020-06-03 Timoteo Carletti , Duccio Fanelli , Sara Nicoletti

This paper studies the mathematical properties of collectively canalizing Boolean functions, a class of functions that has arisen from applications in systems biology. Boolean networks are an increasingly popular modeling framework for…

Discrete Mathematics · Computer Science 2023-06-07 Claus Kadelka , Benjamin Keilty , Reinhard Laubenbacher