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Causality can be described in terms of a structural causal model (SCM) that carries information on the variables of interest and their mechanistic relations. For most processes of interest the underlying SCM will only be partially…

Machine Learning · Computer Science 2021-10-26 Matej Zečević , Devendra Singh Dhami , Petar Veličković , Kristian Kersting

Causality is crucial to understanding the mechanisms behind complex systems and making decisions that lead to intended outcomes. Event sequence data is widely collected from many real-world processes, such as electronic health records, web…

Artificial Intelligence · Computer Science 2020-11-20 Zhuochen Jin , Shunan Guo , Nan Chen , Daniel Weiskopf , David Gotz , Nan Cao

A very important topic in systems biology is developing statistical methods that automatically find causal relations in gene regulatory networks with no prior knowledge of causal connectivity. Many methods have been developed for time…

Machine Learning · Statistics 2012-08-22 Shohei Shimizu

Since interactions in neural systems occur across multiple temporal scales, it is likely that information flow will exhibit a multiscale structure, thus requiring a multiscale generalization of classical temporal precedence causality…

Quantitative Methods · Quantitative Biology 2017-07-13 Sebastiano Stramaglia , Iege Bassez , Luca Faes , Daniele Marinazzo

Current causal discovery approaches require restrictive model assumptions in the absence of interventional data to ensure structure identifiability. These assumptions often do not hold in real-world applications leading to a loss of…

Machine Learning · Statistics 2025-06-25 Anish Dhir , Ruby Sedgwick , Avinash Kori , Ben Glocker , Mark van der Wilk

Granger causality has been employed to investigate causality relations between components of stationary multiple time series. We generalize this concept by developing statistical inference for local Granger causality for multivariate…

Methodology · Statistics 2025-08-12 Yan Liu , Masanobu Taniguchi , Hernando Ombao

Methods for automated discovery of causal relationships from non-interventional data have received much attention recently. A widely used and well understood model family is given by linear acyclic causal models (recursive structural…

Machine Learning · Statistics 2012-05-14 Patrik O. Hoyer , Antti Hyttinen

Identifying directed interactions between species from time series of their population densities has many uses in ecology. This key statistical task is equivalent to causal time series inference, which connects to the Granger causality (GC)…

Populations and Evolution · Quantitative Biology 2020-11-10 Frederic Barraquand , Coralie Picoche , Matteo Detto , Florian Hartig

Estimating causal effects from observational data remains a fundamental challenge in causal inference, especially in the presence of latent confounders. This paper focuses on estimating causal effects in Gaussian Linear Structural Causal…

Machine Learning · Computer Science 2026-01-09 Aurghya Maiti , Prateek Jain

Causal discovery and inference from observational data is an essential problem in statistics posing both modeling and computational challenges. These are typically addressed by imposing strict assumptions on the joint distribution such as…

Machine Learning · Statistics 2024-02-20 Enrico Giudice , Jack Kuipers , Giusi Moffa

Understanding the laws that govern a phenomenon is the core of scientific progress. This is especially true when the goal is to model the interplay between different aspects in a causal fashion. Indeed, causal inference itself is…

Artificial Intelligence · Computer Science 2025-08-27 Alessio Zanga , Elif Ozkirimli , Fabio Stella

Graphical structures estimated by causal learning algorithms from time series data can provide misleading causal information if the causal timescale of the generating process fails to match the measurement timescale of the data. Existing…

Machine Learning · Statistics 2024-05-22 Mohammadsajad Abavisani , David Danks , Sergey Plis

Graph Neural Networks (GNNs) demonstrate their significance by effectively modeling complex interrelationships within graph-structured data. To enhance the credibility and robustness of GNNs, it becomes exceptionally crucial to bolster…

Machine Learning · Computer Science 2023-12-18 Hang Gao , Chengyu Yao , Jiangmeng Li , Lingyu Si , Yifan Jin , Fengge Wu , Changwen Zheng , Huaping Liu

Granger causality is a statistical notion of causal influence based on prediction via vector autoregression. For Gaussian variables it is equivalent to transfer entropy, an information-theoretic measure of time-directed information transfer…

Quantitative Methods · Quantitative Biology 2021-02-17 Sebastiano Stramaglia , Tomas Scagliarini , Yuri Antonacci , Luca Faes

This article presents a novel method for causal discovery with generalized structural equation models suited for analyzing diverse types of outcomes, including discrete, continuous, and mixed data. Causal discovery often faces challenges…

Methodology · Statistics 2023-10-26 Minjie Wang , Xiaotong Shen , Wei Pan

Going beyond correlations, the understanding and identification of causal relationships in observational time series, an important subfield of Causal Discovery, poses a major challenge. The lack of access to a well-defined ground truth for…

Machine Learning · Statistics 2021-04-19 Andrew R. Lawrence , Marcus Kaiser , Rui Sampaio , Maksim Sipos

Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and postgenomics data sets. Indeed, biological entities are not isolated, but are components of complex…

Quantitative Methods · Quantitative Biology 2018-05-07 Alex White , Matthieu Vignes

The broad abundance of time series data, which is in sharp contrast to limited knowledge of the underlying network dynamic processes that produce such observations, calls for a rigorous and efficient method of causal network inference. Here…

Information Theory · Computer Science 2015-05-19 Jie Sun , Dane Taylor , Erik M. Bollt

Discovering causal models from observational and interventional data is an important first step preceding what-if analysis or counterfactual reasoning. As has been shown before, the direction of pairwise causal relations can, under certain…

Machine Learning · Computer Science 2017-01-04 Karamjit Singh , Garima Gupta , Lovekesh Vig , Gautam Shroff , Puneet Agarwal

We consider extension of Granger causality to nonlinear bivariate time series. In this frame, if the prediction error of the first time series is reduced by including measurements from the second time series, then the second time series is…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Nicola Ancona , Daniele Marinazzo , Sebastiano Stramaglia
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