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Recent research has shown that motile cells can adapt their mode of propulsion depending on the environment in which they find themselves. One mode is swimming by blebbing or other shape changes, and in this paper we analyze a class of…

Fluid Dynamics · Physics 2016-10-10 Qixuan Wang , Hans G. Othmer

During migration cells exhibit a rich variety of seemingly random migration patterns, which makes unraveling the underlying mechanisms that control cell migration a daunting challenge. For efficient migration cells require a mechanism for…

Biological Physics · Physics 2020-08-19 Jonathan E. Ron , Pascale Monzo , Nils Gauthier , Raphael Voituriez , Nir S. Gov

Shape changes resulting from segmental flexibility are ubiquitous in molecular and biological systems, and are expected to affect both the diffusive motion and (biological) function of dispersed objects. The recent development of colloidal…

We establish nonlinear stability and asymptotic behavior of traveling periodic waves of viscous conservation laws under localized perturbations or nonlocalized perturbations asymptotic to constant shifts in phase, showing that long-time…

Analysis of PDEs · Mathematics 2012-11-12 Mathew A. Johnson , Pascal Noble , L. Miguel Rodrigues , Kevin Zumbrun

Evolution of the spatial arrangement of cells in a primary culture of cardiac tissue derived from newborn rats was studied experimentally over extended period. It was found that cells attract each other spontaneously to form a clustered…

Cell Behavior · Quantitative Biology 2009-11-13 Takahiro Harada , Akihiro Isomura , Kenichi Yoshikawa

We study the effect of turbulence on marine life by performing numerical simulations of motile microorganisms, modelled as prolate spheroids, in isotropic homogeneous turbulence. We show that the clustering and patchiness observed in…

Biological Physics · Physics 2014-03-20 Caijuan Zhan , Gaetano Sardina , Enkeleida Lushi , Luca Brandt

Active matter consists of units that generate mechanical work by consuming energy. Examples include living systems, such as assemblies of bacteria and biological tissues, biopolymers driven by molecular motors, and suspensions of synthetic…

Soft Condensed Matter · Physics 2021-02-04 Song Liu , Suraj Shankar , M. Cristina Marchetti , Yilin Wu

Belgium is amongst few artificial countries, established on purpose, when Dutch and French speaking parts were joined in a single unit. This makes Belgium a particularly interesting testbed for studying bio-inspired techniques for…

Adaptation and Self-Organizing Systems · Physics 2011-12-21 Andrew Adamatzky , Bernard De Baets , Wesley Van Dessel

Shape anisotropy of individual building blocks plays a crucial role in creating exotic structures and controlling phase behavior in equilibrium systems. We present a combined experimental and simulation study in which we used light-driven…

Soft Condensed Matter · Physics 2026-05-05 Yogesh Shelke , Anpuj Nair S , Hanumantha Rao Vutukuri

Diffusive transport of small molecules within the internal structures of biological and synthetic material systems is complex because the crowded environment presents chemical and physical barriers to mobility. We explored this mobility…

Soft Condensed Matter · Physics 2020-09-29 Rajarshi Guha , Subhadip Ghosh , Darrell Velegol , Peter J. Butler , Ayusman Sen , Jennifer L. Ross

Cilia and flagella are hairlike organelles that propel cells through fluid. The active motion of the axoneme, the motile structure inside cilia and flagella, is powered by molecular motors of the dynein family. These motors generate forces…

Subcellular Processes · Quantitative Biology 2016-11-02 Pablo Sartori , Veikko Geyer , Jonathon Howard , Frank Jülicher

We report experimental laboratory studies on developing conductive pathways, or wires, using protoplasmic tubes of plasmodium of acellular slime mould Physarum polycephalum. Given two pins to be connected by a wire, we place a piece of…

Biological Physics · Physics 2013-09-17 Andrew Adamatzky

We present a model of soft active particles that leads to a rich array of collective behavior found also in dense biological swarms of bacteria and other unicellular organisms. Our model uses only local interactions, such as Vicsek-type…

Soft Condensed Matter · Physics 2016-10-13 Ruben van Drongelen , Anshuman Pal , Carl P. Goodrich , Timon Idema

Understanding the role of self-propulsion on the conformational properties of active filamentous objects has relevance in biology. In this context, we consider a flexible bead-spring model polymer for which along with both attractive and…

Soft Condensed Matter · Physics 2022-02-22 Subhajit Paul , Suman Majumder , Wolfhard Janke

Cytoskeletal gels are engineered prototypes that mimic the contractile behavior of a cell in-vitro. They are composed of an active polymer matrix and a liquid solvent. Their contraction kinetics is governed by two dynamic phenomena:…

Soft Condensed Matter · Physics 2023-06-01 Matteo Ferraresso , Mohammad Shojaeifard , Albert Kong , Mattia Bacca

Mesh-like structures, such as mucus gel or cytoskeleton networks, are ubiquitous in biological systems. These intricate structures are composed of cross-linked, semi-flexible bio-filaments, crucial to numerous biological processes. In many…

Soft Condensed Matter · Physics 2024-01-10 Yeongjin Kim , Won Kyu Kim , Jae-Hyung Jeon

Transport phenomena in out-of-equilibrium systems is immensely important in a myriad of applications in biology, engineering and physics. Complex environments, such as the cytoplasm or porous media, can substantially affect the transport…

Soft Condensed Matter · Physics 2020-02-18 Shahrzad Yazdi , Juan L. Aragones , Jennifer Coulter , Alfredo Alexander-Katz

Low Reynolds number direct simulations of large populations of hydrodynamically interacting swimming particles confined between planar walls are performed. The results of simulations are compared with a theory that describes dilute…

Fluid Dynamics · Physics 2015-05-13 Juan P. Hernandez-Ortiz , Patrick T. Underhill , Michael D. Graham

Cells and tissues exert forces and can actively change shape. This strikingly autonomous behavior is powered by the cytoskeleton, which includes an active gel of actin filaments, crosslinks, and myosin molecular motors. Although individual…

Soft Condensed Matter · Physics 2017-07-26 José Alvarado , Misha Sheinman , Abhinav Sharma , Fred C. MacKintosh , Gijsje H. Koenderink

Motor proteins drive persistent motion and self-organisation of cytoskeletal filaments. However, state-of-the-art microscopy techniques and continuum modelling approaches focus on large length and time scales. Here, we perform…

Soft Condensed Matter · Physics 2024-06-03 Gerrit Vliegenthart , Arvind Ravichandran , Marisol Ripoll , Thorsten Auth , Gerhard Gompper