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Consider observing an undirected network that is `noisy' in the sense that there are Type I and Type II errors in the observation of edges. Such errors can arise, for example, in the context of inferring gene regulatory networks in genomics…

Machine Learning · Statistics 2014-01-03 Prakash Balachandran , Edoardo Airoldi , Eric Kolaczyk

Phage display is a powerful laboratory technique used to study the interactions between proteins and other molecules, whether other proteins, peptides, DNA or RNA. The under-utilisation of this data in conjunction with deep learning models…

Populations and Evolution · Quantitative Biology 2026-01-08 Ilann Amiaud-Plachy , Michael Blank , Oliver Bent , Sebastien Boyer

A method is proposed to generate an optimal fit of a number of connected linear trend segments onto time-series data. To be able to efficiently handle many lines, the method employs a stochastic search procedure to determine optimal…

Quantitative Methods · Quantitative Biology 2017-04-11 Myrl G. Marmarelis

This paper proposes a novel model inference procedure to identify system matrix from a single noisy trajectory over a finite-time interval. The proposed inference procedure comprises an observation data processor, a redundant data processor…

Systems and Control · Electrical Eng. & Systems 2021-01-05 Yanbing Mao , Naira Hovakimyan , Petros Voulgaris , Lui Sha

Approximate Bayesian Computation is widely used in systems biology for inferring parameters in stochastic gene regulatory network models. Its performance hinges critically on the ability to summarize high-dimensional system responses such…

Machine Learning · Statistics 2021-04-13 Mattias Åkesson , Prashant Singh , Fredrik Wrede , Andreas Hellander

Inference algorithms for arbitrary belief networks are impractical for large, complex belief networks. Inference algorithms for specialized classes of belief networks have been shown to be more efficient. In this paper, we present a…

Artificial Intelligence · Computer Science 2013-02-18 Kurt Huang , Max Henrion

Stochastic process discovery is concerned with deriving a model capable of reproducing the stochastic character of observed executions of a given process, stored in a log. This leads to an optimisation problem in which the model's parameter…

Formal Languages and Automata Theory · Computer Science 2025-05-01 Pierre Cry , Paolo Ballarini , András Horváth , Pascale Le Gall

The problem of finding the optimal set of source nodes in a diffusion network that maximizes the spread of information, influence, and diseases in a limited amount of time depends dramatically on the underlying temporal dynamics of the…

Social and Information Networks · Computer Science 2012-05-09 Manuel Gomez Rodriguez , Bernhard Schölkopf

Observing the internal state of the whole system using a small number of sensor nodes is important in analysis of complex networks. Here, we study the problem of determining the minimum number of sensor nodes to discriminate attractors…

Data Structures and Algorithms · Computer Science 2021-06-14 Xiaoqing Cheng , Wai-Ki Ching , Sini Guo , Tatsuya Akutsu

The increasing integration of intermittent renewable generation, especially at the distribution level,necessitates advanced planning and optimisation methodologies contingent on the knowledge of thegrid, specifically the admittance matrix…

Systems and Control · Electrical Eng. & Systems 2021-12-21 Jean-Sébastien Brouillon , Emanuele Fabbiani , Pulkit Nahata , Keith Moffat , Florian Dörfler , Giancarlo Ferrari-Trecate

We consider the problem of identifying the most influential nodes for a spreading process on a network when prior knowledge about structure and dynamics of the system is incomplete or erroneous. Specifically, we perform a numerical analysis…

Physics and Society · Physics 2018-10-09 Şirag Erkol , Ali Faqeeh , Filippo Radicchi

We present an efficient, principled, and interpretable technique for inferring module assignments and for identifying the optimal number of modules in a given network. We show how several existing methods for finding modules can be…

Data Analysis, Statistics and Probability · Physics 2008-06-23 Jake M. Hofman , Chris H. Wiggins

The characterisation of quantum networks is fundamental to understanding how energy and information propagates through complex systems, with applications in control, communication, error mitigation and energy transfer. In this work, we…

Quantum Physics · Physics 2025-09-19 Conall J. Campbell , Matthew Mackinnon , Mauro Paternostro , Diana A. Chisholm

Latent space models have been widely adopted in modeling network data. Developing statistical inference for estimated model parameters enables quantifying associated uncertainty and is pivotal for downstream tasks. Despite recent progress…

Statistics Theory · Mathematics 2026-05-12 Yuang Tian , Jiajin Sun , Yinqiu He

We demonstrate the use of computational phylogenetic techniques to solve a central problem in inferential network monitoring. More precisely, we design a novel algorithm for multicast-based delay inference, i.e. the problem of…

Probability · Mathematics 2011-09-07 Shankar Bhamidi , Ram Rajagopal , Sebastien Roch

Bayesian networks (BNs) are probabilistic graphical models for describing complex joint probability distributions. The main problem for BNs is inference: Determine the probability of an event given observed evidence. Since exact inference…

Programming Languages · Computer Science 2018-03-01 Kevin Batz , Benjamin Lucien Kaminski , Joost-Pieter Katoen , Christoph Matheja

We have used Bayesian Optimisation (BO) to find hyper-parameters in an existing biologically plausible population neural network. The 8-dimensional optimal hyper-parameter combination should be such that the network dynamics simulate the…

Quantitative Methods · Quantitative Biology 2021-04-14 Mahak Kothari , Swapna Sasi , Jun Chen , Elham Zareian , Basabdatta Sen Bhattacharya

We present and discuss the results of an experimental analysis in the design of Boolean networks by means of genetic algorithms. A population of networks is evolved with the aim of finding a network such that the attractor it reaches is of…

Neural and Evolutionary Computing · Computer Science 2011-02-01 Andrea Roli , Cristian Arcaroli , Marco Lazzarini , Stefano Benedettini

One major challenge for living cells is the measurement and prediction of signals corrupted by noise. In general, cells need to make decisions based on their compressed representation of noisy, time-varying signals. Strategies for signal…

Quantitative Methods · Quantitative Biology 2023-07-07 Jenny Poulton , Age Tjalma , Lotte Slim , Pieter Rein ten Wolde

While modern machine learning has transformed numerous application domains, its growing computational demands increasingly constrain scalability and efficiency, particularly on embedded and resource-limited platforms. In practice, neural…

Machine Learning · Computer Science 2025-10-30 Bernhard Klein