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Accurate segmentation of brain tumors in MRI scans is essential for reliable clinical diagnosis and effective treatment planning. Recently, diffusion models have demonstrated remarkable effectiveness in image generation and segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Sara Yavari , Rahul Nitin Pandya , Jacob Furst

In recent times, denoising diffusion probabilistic models (DPMs) have proven effective for medical image generation and denoising, and as representation learners for downstream segmentation. However, segmentation performance is limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Venkata Siddharth Dhara , Pawan Kumar

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

In medical imaging, segmentation models have known a significant improvement in the past decade and are now used daily in clinical practice. However, similar to classification models, segmentation models are affected by adversarial attacks.…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Othmane Laousy , Alexandre Araujo , Guillaume Chassagnon , Nikos Paragios , Marie-Pierre Revel , Maria Vakalopoulou

Prostate specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) imaging provides a tremendously exciting frontier in visualization of prostate cancer (PCa) metastatic lesions. However, accurate…

Medical Physics · Physics 2024-12-05 Amirhosein Toosi , Sara Harsini , François Bénard , Carlos Uribe , Arman Rahmim

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

Denoising diffusion models (DDM) have gained recent traction in medical image translation given improved training stability over adversarial models. DDMs learn a multi-step denoising transformation to progressively map random Gaussian-noise…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Fuat Arslan , Bilal Kabas , Onat Dalmaz , Muzaffer Ozbey , Tolga Çukur

Leveraging the powerful capabilities of diffusion models has yielded quite effective results in medical image segmentation tasks. However, existing methods typically transfer the original training process directly without specific…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Qilin Huang , Tianyu Lin , Zhiguang Chen , Fudan Zheng

Generalization to previously unseen images with potential domain shifts and different styles is essential for clinically applicable medical image segmentation, and the ability to disentangle domain-specific and domain-invariant features is…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Ran Gu , Guotai Wang , Jiangshan Lu , Jingyang Zhang , Wenhui Lei , Yinan Chen , Wenjun Liao , Shichuan Zhang , Kang Li , Dimitris N. Metaxas , Shaoting Zhang

Understanding the morphological structure of medical images and precisely segmenting the region of interest or abnormality is an important task that can assist in diagnosis. However, the unique properties of medical imaging make clear…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Sungmin Kang , Jaeha Song , Jihie Kim

Although numerous improvements have been made in the field of image segmentation using convolutional neural networks, the majority of these improvements rely on training with larger datasets, model architecture modifications, novel loss…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Saied Asgari Taghanaki , Kumar Abhishek , Ghassan Hamarneh

Medical image segmentation is a challenging task with inherent ambiguity and high uncertainty, attributed to factors such as unclear tumor boundaries and multiple plausible annotations. The accuracy and diversity of segmentation masks are…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Tao Chen , Chenhui Wang , Hongming Shan

Medical image segmentation is critical for diagnosing and treating spinal disorders. However, the presence of high noise, ambiguity, and uncertainty makes this task highly challenging. Factors such as unclear anatomical boundaries,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-13 Zhiqing Zhang , Guojia Fan , Tianyong Liu , Nan Li , Yuyang Liu , Ziyu Liu , Canwei Dong , Shoujun Zhou

Many self-supervised denoising approaches have been proposed in recent years. However, these methods tend to overly smooth images, resulting in the loss of fine structures that are essential for medical applications. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2025-04-02 Basar Demir , Yikang Liu , Xiao Chen , Eric Z. Chen , Lin Zhao , Boris Mailhe , Terrence Chen , Shanhui Sun

Multi-modal magnetic resonance imaging (MRI) provides rich, complementary information for analyzing diseases. However, the practical challenges of acquiring multiple MRI modalities, such as cost, scan time, and safety considerations, often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Zhaohu Xing , Sicheng Yang , Sixiang Chen , Tian Ye , Yijun Yang , Jing Qin , Lei Zhu

Sparse-view Computed Tomography (CT) image reconstruction is a promising approach to reduce radiation exposure, but it inevitably leads to image degradation. Although diffusion model-based approaches are computationally expensive and suffer…

Image and Video Processing · Electrical Eng. & Systems 2024-03-15 Hanyu Chen , Zhixiu Hao , Lin Guo , Liying Xiao

Medical image segmentation, particularly in multi-domain scenarios, requires precise preservation of anatomical structures across diverse representations. While deep learning has advanced this field, existing models often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Afshin Bozorgpour , Sina Ghorbani Kolahi , Reza Azad , Ilker Hacihaliloglu , Dorit Merhof

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

In medical imaging, the diffusion models have shown great potential for synthetic image generation tasks. However, these approaches often lack the interpretable connections between the generated and real images and can create anatomically…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Jian-Qing Zheng , Yuanhan Mo , Yang Sun , Jiahua Li , Fuping Wu , Ziyang Wang , Tonia Vincent , Bartłomiej W. Papież