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Video face re-aging deals with altering the apparent age of a person to the target age in videos. This problem is challenging due to the lack of paired video datasets maintaining temporal consistency in identity and age. Most re-aging…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Abdul Muqeet , Kyuchul Lee , Bumsoo Kim , Yohan Hong , Hyungrae Lee , Woonggon Kim , KwangHee Lee

The ability to identify time periods when individuals are most susceptible to exposures, as well as the biological mechanisms through which these exposures act, is of great public health interest. Growing evidence supports an association…

Photoplethysmography (PPG) is emerging as a crucial tool for monitoring human hemodynamics, with recent studies highlighting its potential in assessing vascular aging through deep learning. However, real-world age distributions are often…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Guangkun Nie , Qinghao Zhao , Gongzheng Tang , Jun Li , Shenda Hong

Gene regulation is an important fundamental biological process. The regulation of gene expression is managed through a variety of methods including epigenetic processes (e.g., DNA methylation). Understanding the role of epigenetic changes…

Molecular Networks · Quantitative Biology 2021-06-01 James Brunner , Jacob Kim , Timothy Downing , Eric Mjolsness , Kord M. Kober

Since it is difficult to collect face images of the same subject over a long range of age span, most existing face aging methods resort to unpaired datasets to learn age mappings. However, the matching ambiguity between young and aged face…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Yunfan Liu , Qi Li , Zhenan Sun

Automated cephalometric landmark detection is crucial in real-world orthodontic diagnosis. Current studies mainly focus on only adult subjects, neglecting the clinically crucial scenario presented by adolescents whose landmarks often…

Computer Vision and Pattern Recognition · Computer Science 2024-06-19 Han Wu , Chong Wang , Lanzhuju Mei , Tong Yang , Min Zhu , Dingggang Shen , Zhiming Cui

The study of genetic variants can help find correlating population groups to identify cohorts that are predisposed to common diseases and explain differences in disease susceptibility and how patients react to drugs. Machine learning…

This study develops a methodology by capturing both the battery aging state and degradation rate for improved life prediction performance. The aging state is indicated by six physical features of an equivalent circuit model that are…

Machine Learning · Computer Science 2023-08-29 Mingyuan Zhao , Yongzhi Zhang

Age estimation is an important yet very challenging problem in computer vision. Existing methods for age estimation usually apply a divide-and-conquer strategy to deal with heterogeneous data caused by the non-stationary aging process.…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Wanhua Li , Jiwen Lu , Jianjiang Feng , Chunjing Xu , Jie Zhou , Qi Tian

Human genetic diseases often arise from point mutations, emphasizing the critical need for precise genome editing techniques. Among these, base editing stands out as it allows targeted alterations at the single nucleotide level. However,…

Genomics · Quantitative Biology 2023-11-16 Amina Mollaysa , Ahmed Allam , Michael Krauthammer

Human genetic diseases often arise from point mutations, emphasizing the critical need for precise genome editing techniques. Among these, base editing stands out as it allows targeted alterations at the single nucleotide level. However,…

Machine Learning · Computer Science 2023-11-13 Amina Mollaysa , Ahmed Allam , Michael Krauthammer

Generative modeling has recently seen many exciting developments with the advent of deep generative architectures such as Variational Auto-Encoders (VAE) or Generative Adversarial Networks (GAN). The ability to draw synthetic i.i.d.…

Machine Learning · Computer Science 2021-02-19 Johan Leduc , Nicolas Grislain

Human age estimation has attracted increasing researches due to its wide applicability in such as security monitoring and advertisement recommendation. Although a variety of methods have been proposed, most of them focus only on the…

Computer Vision and Pattern Recognition · Computer Science 2016-09-14 Qing Tian , Songcan Chen , Xiaoyang Tan

Studying the morphological development of cartilaginous and osseous structures is critical to the early detection of life-threatening skeletal dysmorphology. Embryonic cartilage undergoes rapid structural changes within hours, introducing…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Nishchal Sapkota , Yejia Zhang , Susan M. Motch Perrine , Yuhan Hsi , Sirui Li , Meng Wu , Greg Holmes , Abdul R. Abdulai , Ethylin W. Jabs , Joan T. Richtsmeier , Danny Z Chen

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

Machine Learning · Computer Science 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho

The nematode Caenorhabditis elegans (C. elegans) serves as an important model organism in a wide variety of biological studies. In this paper we introduce a pipeline for automated analysis of C. elegans imagery for the purpose of studying…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Linfeng Wang , Shu Kong , Zachary Pincus , Charless Fowlkes

Although impressive results have been achieved for age progression and regression, there remain two major issues in generative adversarial networks (GANs)-based methods: 1) conditional GANs (cGANs)-based methods can learn various effects…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Zhizhong Huang , Junping Zhang , Hongming Shan

In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics. One key problem is to identify aberrant patterns of these processes and…

Applications · Statistics 2012-10-03 Matthias Kormaksson , James G. Booth , Maria E. Figueroa , Ari Melnick

Motivation: Since susceptibility to diseases increases with age, studying aging gains importance. Analyses of gene expression or sequence data, which have been indispensable for investigating aging, have been limited to studying genes and…

Computational Engineering, Finance, and Science · Computer Science 2013-07-15 Fazle Elahi Faisal , Tijana Milenkovic

Biological age scores are an emerging tool to characterize aging by estimating chronological age based on physiological biomarkers. Various scores have shown associations with aging-related outcomes. This study assessed the relation between…