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A Deep Autoencoder based content retrieval algorithm is proposed for prediction and differentiation of cancer types based on the presence of epigenetic patterns of DNA methylation identified in genetic regions known as CpG islands. The…

Quantitative Methods · Quantitative Biology 2018-10-08 Mohammed Khwaja , Melpomeni Kalofonou , Chris Toumazou

Among the different biomarkers of aging based on omics and clinical data, DNA methylation clocks stand apart providing unmatched accuracy in assessing the biological age of both humans and animal models of aging. Here, we discuss robustness…

Genomics · Quantitative Biology 2018-11-16 Dmitriy I. Podolskiy , Vadim N. Gladyshev

This work introduces a novel deep-learning approach for estimating age from a single facial image by refining an initial age estimate. The refinement leverages a reference face database of individuals with similar ages and appearances. We…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Ran Sandhaus , Yosi Keller

Machine learning is a rapidly evolving field with a wide range of applications, including biological signal analysis, where novel algorithms often improve the state-of-the-art. However, robustness to algorithmic variability - measured by…

Signal Processing · Electrical Eng. & Systems 2024-02-16 Tobias Ettling , Sari Saba-Sadiya , Gemma Roig

Age progression and regression refers to aesthetically render-ing a given face image to present effects of face aging and rejuvenation, respectively. Although numerous studies have been conducted in this topic, there are two major problems:…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Qi Li , Yunfan Liu , Zhenan Sun

As the global population continues to age, there is an increasing demand for ways to accurately quantify the biological processes underlying aging. Biological age, unlike chronological age, reflects an individual's physiological state,…

Quantitative Methods · Quantitative Biology 2025-08-29 Jared A Kushner , Mohit Pandey , Sandeep , S Kohli

Face-based age estimation has attracted enormous attention due to wide applications to public security surveillance, human-computer interaction, etc. With vigorous development of deep learning, age estimation based on deep neural network…

Computer Vision and Pattern Recognition · Computer Science 2022-05-23 Zhicheng Cao , Kaituo Zhang , Liaojun Pang , Heng Zhao

The ability to accurately recognize an individual's face with respect to human aging factor holds significant importance for various private as well as government sectors such as customs and public security bureaus, passport office, and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Wang Yao , Muhammad Ali Farooq , Joseph Lemley , Peter Corcoran

The Convolutional Neural Network has amazed us with its usage on several applications. Age range estimation using CNN is emerging due to its application in myriad of areas which makes it a state-of-the-art area for research and improve the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Dipesh Gyawali , Prashanga Pokharel , Ashutosh Chauhan , Subodh Chandra Shakya

Deep learning has significantly advanced electrocardiogram (ECG) analysis, enabling automatic annotation, disease screening, and prognosis beyond traditional clinical capabilities. However, understanding these models remains a challenge,…

Machine Learning · Computer Science 2025-09-19 Ahcène Boubekki , Konstantinos Patlatzoglou , Joseph Barker , Fu Siong Ng , Antônio H. Ribeiro

Methylation of CpG dinucleotides is a prevalent epigenetic modification that is required for proper development in vertebrates, and changes in CpG methylation are essential to cellular differentiation. Genome-wide DNA methylation assays…

Genomics · Quantitative Biology 2014-08-28 John A. Capra , Dennis Kostka

Objectives: Age and gender estimation is crucial for various applications, including forensic investigations and anthropological studies. This research aims to develop a predictive system for age and gender estimation in living individuals,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Mohsin Ali , Haider Raza , John Q Gan , Ariel Pokhojaev , Matanel Katz , Esra Kosan , Dian Agustin Wahjuningrum , Omnina Saleh , Rachel Sarig , Akhilanada Chaurasia

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

DNA Methylation has been the most extensively studied epigenetic mark. Usually a change in the genotype, DNA sequence, leads to a change in the phenotype, observable characteristics of the individual. But DNA methylation, which happens in…

Genomics · Quantitative Biology 2018-07-26 Soham Chatterjee , Archana Iyer , Satya Avva , Abhai Kollara , Malaikannan Sankarasubbu

Purpose: Chest X-rays are essential for diagnosing pulmonary conditions, but limited access in resource-constrained settings can delay timely diagnosis. Electrocardiograms (ECGs), in contrast, are widely available, non-invasive, and often…

Signal Processing · Electrical Eng. & Systems 2025-09-23 Julia Matejas , Olaf Żurawski , Nils Strodthoff , Juan Miguel Lopez Alcaraz

Age estimation is a technique for predicting human ages from digital facial images, which analyzes a person's face image and estimates his/her age based on the year measure. Nowadays, intelligent age estimation and age synthesis have become…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Milad Taleby Ahvanooey , Qianmu Li

Identification of human genes involved in the aging process is critical due to the incidence of many diseases with age. A state-of-the-art approach for this purpose infers a weighted dynamic aging-specific subnetwork by mapping gene…

Molecular Networks · Quantitative Biology 2022-05-27 Qi Li , Khalique Newaz , Tijana Milenković

The last decade or two has witnessed a boom of images. With the increasing ubiquity of cameras and with the advent of selfies, the number of facial images available in the world has skyrocketed. Consequently, there has been a growing…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Vikas Sheoran , Shreyansh Joshi , Tanisha R. Bhayani

Different people age in different ways. Learning a personalized age estimator for each person is a promising direction for age estimation given that it better models the personalization of aging processes. However, most existing…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Wanhua Li , Jiwen Lu , Abudukelimu Wuerkaixi , Jianjiang Feng , Jie Zhou

Identifying differentially methylated cytosine-guanine dinucleotide (CpG) sites between benign and tumour samples can assist in understanding disease. However, differential analysis of bounded DNA methylation data often requires data…