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Magnetic resonance imaging (MRI) is an effective imaging modality for identifying and localizing breast lesions in women. Accurate and precise lesion segmentation using a computer-aided-diagnosis (CAD) system, is a crucial step in…
Background and Purpose: Identifying the thromboembolism source in ischemic stroke is crucial for treatment and secondary prevention yet is often undetermined. This study describes a self-supervised deep learning approach in digital…
The analysis of carotid arteries, particularly plaques, in multi-sequence Magnetic Resonance Imaging (MRI) data is crucial for assessing the risk of atherosclerosis and ischemic stroke. In order to evaluate metrics and radiomic features,…
Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…
Lesion segmentation is a core task for quantitative analysis of MRI scans of Multiple Sclerosis patients. The recent success of deep learning techniques in a variety of medical image analysis applications has renewed community interest in…
Accurate segmentation of Multiple Sclerosis (MS) lesions in longitudinal MRI scans is crucial for monitoring disease progression and treatment efficacy. Although changes across time are taken into account when assessing images in clinical…
Deep neural networks have demonstrated very promising performance on accurate segmentation of challenging organs (e.g., pancreas) in abdominal CT and MRI scans. The current deep learning approaches conduct pancreas segmentation by…
Medical imaging spans diverse tasks and modalities which play a pivotal role in disease diagnosis, treatment planning, and monitoring. This study presents a novel exploration, being the first to systematically evaluate segmentation,…
Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…
Breast cancer is the second most common type of cancer in women in Canada and the United States, representing over 25\% of all new female cancer cases. As such, there has been immense research and progress on improving screening and…
Brain stroke has become a significant burden on global health and thus we need remedies and prevention strategies to overcome this challenge. For this, the immediate identification of stroke and risk stratification is the primary task for…
Clinical diagnostic and treatment decisions rely upon the integration of patient-specific data with clinical reasoning. Cancer presents a unique context that influence treatment decisions, given its diverse forms of disease evolution.…
The preservation of the corticospinal tract (CST) is key to good motor recovery after stroke. The gold standard method of assessing the CST with imaging is diffusion tensor tractography. However, this is not available for most intracerebral…
Stroke is globally a major cause of mortality and morbidity, and hence accurate and rapid diagnosis of stroke is valuable. Retinal fundus imaging reveals the known markers of elevated stroke risk in the eyes, which are retinal venular…
Sub-cortical brain structure segmentation in Magnetic Resonance Images (MRI) has attracted the interest of the research community for a long time because morphological changes in these structures are related to different neurodegenerative…
Clinical application of high-resolution diffusion MRI is hindered by hardware limitations and prohibitive scan times, motivating computational super-resolution. This study investigates the efficacy of a feature-based loss function in…
Deep learning approaches for diffusion MRI have so far focused primarily on voxel-based segmentation of lesions or white-matter fiber tracts. A drawback of representing tracts as volumetric labels, rather than sets of streamlines, is that…
Collateral circulation results from specialized anastomotic channels which are capable of providing oxygenated blood to regions with compromised blood flow caused by ischemic injuries. The quality of collateral circulation has been…
Diffusion-weighted magnetic resonance imaging (DW-MRI) is the only non-invasive approach for estimation of intra-voxel tissue microarchitecture and reconstruction of in vivo neural pathways for the human brain. With improvement in…
Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based pancreatic segmentation is more established, MRI-based segmentation methods are…