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The classic model of eukaryotic gene expression requires direct spatial contact between a distal enhancer and a proximal promoter. Recent Chromosome Conformation Capture (3C) studies show that enhancers and promoters are embedded in a…

Genomics · Quantitative Biology 2014-11-25 Boryana Doyle , Geoffrey Fudenberg , Maxim Imakaev , Leonid A. Mirny

Topological constraints (TCs) between polymers determine the behaviour of complex fluids such as creams, oils and plastics. Most of the polymer solutions used every day life employ linear chains; their behaviour is accurately captured by…

Soft Condensed Matter · Physics 2020-10-07 Fabio Landuzzi , Takenobu Nakamura , Davide Michieletto , Takahiro Sakaue

Structural organization and correlations are studied in very large packings of equally sized acrylic spheres, reconstructed in three-dimensions by means of X-ray computed tomography. A novel technique, devised to analyze correlations among…

Soft Condensed Matter · Physics 2007-09-19 Tomaso Aste

We discuss the entropy of a circular polymer under a topological constraint. We call it the {\it topological entropy} of the polymer, in short. A ring polymer does not change its topology (knot type) under any thermal fluctuations. Through…

Statistical Mechanics · Physics 2009-11-07 Miyuki K. Shimamura , Tetso Deguchi

At low temperatures, colloidal particles with short-range attractive and long-range repulsive interactions can form various periodic microphases in bulk.In this paper, we investigate the self-assembly behaviour of colloids with competing…

Soft Condensed Matter · Physics 2023-12-12 Ningyi Li , Junhong Li , Lijingting Qing , Shicheng Ma , Yao Li , Baohui Li

The statistical mechanics of a long knotted collapsed polymer is determined by a free-energy with a knot-dependent subleading term, which is linked to the length of the shortest polymer that can hold such knot. The only other parameter…

Statistical Mechanics · Physics 2014-12-01 Marco Baiesi , Enzo Orlandini , Attilio L. Stella

We propose a two-body spherically symmetric (isotropic) potential such that particles interacting by the potential self assemble into linear semiflexible polymeric chains without branching. By suitable control of the potential parameters we…

Soft Condensed Matter · Physics 2018-05-09 Alex Abraham , Apratim Chatterji

It is nontrivial whether the average size of a ring polymer should become smaller or larger under a topological constraint. Making use of some knot invariants, we evaluate numerically the mean square radius of gyration for ring polymers…

Statistical Mechanics · Physics 2016-08-31 Miyuki K. Shimamura , Tetsuo Deguchi

At sufficiently low temperatures and high densities, repulsive spherical particles in two-dimensions (2d) form close-packed structures with six-fold symmetry. By contrast, when the interparticle interaction has an attractive anisotropic…

Soft Condensed Matter · Physics 2018-09-13 T. Geigenfeind , C. S. Dias , M. M. Telo da Gama , D. de las Heras , N. A. M. Araújo

Here we report on the translocation of folded polymers through nano-pores using molecular dynamic simulations. Two cases are studied; one in which a folded molecule unfolds upon passage and one in which the folding remains intact as the…

Soft Condensed Matter · Physics 2016-03-23 Narges Nikoofard , Alireza Mashaghi

Polymers in a melt may be subject to topological constraints, as in the example of unlinked polymer rings. How to do statistical mechanics in the presence of such constraints remains a fundamental open problem. We study the effect of…

Statistical Mechanics · Physics 2015-12-04 Pablo Serna , Guy Bunin , Adam Nahum

Ring polymers remain a major challenge to our current understanding of polymer dynamics. Experimental results are difficult to interpret because of the uncertainty in the purity and dispersity of the sample. Using both equilibrium and…

Soft Condensed Matter · Physics 2015-06-03 Jonathan D. Halverson , Gary S. Grest , Alexander Y. Grosberg , Kurt Kremer

Semiflexible polymers are ubiquitous in natural and artificial systems, where their intermediate rigidity gives rise to rich structural and dynamical behavior. Confinement plays a central role in these behaviors, as spatial restrictions can…

Soft Condensed Matter · Physics 2026-03-31 Nasir Amiri , Jonathan P. Singer , Xin Yong

Macromolecular crowding can influence polymer shapes, which is important for understanding the thermodynamic stability of polymer solutions and the structure and function of biopolymers (proteins, RNA, DNA) under confinement. We explore the…

Soft Condensed Matter · Physics 2014-10-27 Wei Kang Lim , Alan R. Denton

We examine entanglements using monomer contacts between pairs of chains in a Brownian-dynamics simulation of a polymer melt. A map of contact positions with respect to the contacting monomer numbers (i,j) shows clustering in small regions…

Condensed Matter · Physics 2009-10-28 E. Ben-Naim , G. S. Grest , T. A. Witten , A. R. C. Baljon

Here we investigate the connection between topological order and the geometric entanglement, as measured by the logarithm of the overlap between a given state and its closest product state of blocks. We do this for a variety of…

Strongly Correlated Electrons · Physics 2014-10-28 Roman Orus , Tzu-Chieh Wei , Oliver Buerschaper , Maarten Van den Nest

Hydrodynamic interactions as modeled by Multi-Particle Collision Dynamics can dramatically influence the dynamics of fully flexible, ring-shaped polymers in ways not known for any other polymer architecture or topology. We show that steady…

Soft Condensed Matter · Physics 2019-09-09 M. Liebetreu , C. N. Likos

Equilibrium states of a closed semiflexible polymer binding to a cylinder are described. This may be either by confinement or by constriction. Closed completely bound states are labeled by two integers: the number of oscillations, $n$, and…

Soft Condensed Matter · Physics 2017-11-17 Pablo Vázquez-Montejo , Zachary McDargh , Markus Deserno , Jemal Guven

The interplay of topological constraints and persistence length of ring polymers in their own melt is investigated by means of dynamical Monte Carlo simulations of a three dimensional lattice model. We ask if the results are consistent with…

Statistical Mechanics · Physics 2009-10-31 M. Muller , J. P. Wittmer , M. E. Cates

Polymer translocation in crowded environments is a ubiquitous phenomenon in biological systems. We studied polymer translocation through a pore in free, one-sided (asymmetric), and two-sided (symmetric) crowded environments. Extensive…

Soft Condensed Matter · Physics 2024-03-01 Vrinda Garg , Rejoy Mathew , Riyan Ibrahim , Kulveer Singh , Surya K. Ghosh