English
Related papers

Related papers: Molecule-dynamic-based Aging Clock and Aging Roadm…

200 papers

We introduce Sundial, a family of native, flexible, and scalable time series foundation models. To predict the next-patch's distribution, we propose a TimeFlow Loss based on flow-matching, which facilitates native pre-training of…

Machine Learning · Computer Science 2026-05-12 Yong Liu , Guo Qin , Zhiyuan Shi , Zhi Chen , Caiyin Yang , Xiangdong Huang , Jianmin Wang , Mingsheng Long

We use confocal microscopy to directly visualize the dynamics of aging colloidal glasses. We prepare a colloidal suspension at high density, a simple model system which shares many properties with other glasses, and initiate experiments by…

Disordered Systems and Neural Networks · Physics 2009-11-07 Rachel E. Courtland , Eric R. Weeks

The gradual accumulation of damage and dysregulation during the aging of living organisms can be quantified. Even so, the aging process is complex and has multiple interacting physiological scales -- from the molecular to cellular to whole…

Quantitative Methods · Quantitative Biology 2021-05-06 Spencer Farrell , Garrett Stubbings , Kenneth Rockwood , Arnold Mitnitski , Andrew Rutenberg

We propose a new theory for aging based on dynamical systems and provide a data-driven computational method to quantify the changes at the cellular level. We use ergodic theory to decompose the dynamics of changes during aging and show that…

Quantitative Methods · Quantitative Biology 2025-04-18 Farhan Khodaee , Rohola Zandie , Yufan Xia , Elazer R. Edelman

Biological aging is characterized by an age-dependent increase in the probability of death and by a decrease in the reproductive capacity. Individual age-dependent rates of survival and reproduction have a strong impact on population…

Populations and Evolution · Quantitative Biology 2016-02-03 Arian Šajina , Dario Riccardo Valenzano

Modeling how individuals evolve over time is a fundamental problem in the natural and social sciences. However, existing datasets are often cross-sectional with each individual observed only once, making it impossible to apply traditional…

Machine Learning · Computer Science 2019-03-06 Emma Pierson , Pang Wei Koh , Tatsunori Hashimoto , Daphne Koller , Jure Leskovec , Nicholas Eriksson , Percy Liang

We describe a percolation-type approach to modeling of the processes of aging and certain other properties of tissues analyzed as systems consisting of interacting cells. Tissues are considered as structures made of regular healthy,…

Statistical Mechanics · Physics 2016-01-28 Vladimir Privman , Vyacheslav Gorshkov , Sergiy Libert

We use confocal microscopy to study the aging of a bidisperse colloidal glass near rough and smooth boundaries. Near smooth boundaries, the particles form layers, and particle motion is dramatically slower near the boundary as compared to…

Soft Condensed Matter · Physics 2017-12-14 Cong Cao , Xinru Huang , Connie B. Roth , Eric R. Weeks

Aging is a highly complex and heterogeneous process that progresses at different rates across individuals, making biological age (BA) a more accurate indicator of physiological decline than chronological age. While previous studies have…

Genomics · Quantitative Biology 2025-10-24 Huifa Li , Feilong Tang , Haochen Xue , Yulong Li , Xinlin Zhuang , Bin Zhang , Eran Segal , Imran Razzak

Scaled Brownian motion (SBM) is widely used to model anomalous diffusion of passive tracers in complex and biological systems. It is a highly non-stationary process governed by the Langevin equation for Brownian motion, however, with a…

Statistical Mechanics · Physics 2015-06-23 H. Safdari , A. V. Chechkin , G. R. Jafari , R. Metzler

Aging is thought to be a consequence of intrinsic breakdowns in how genetic information is processed. But mounting experimental evidence suggests that aging can be slowed. To help resolve this mystery, I derive a mortality equation which…

Populations and Evolution · Quantitative Biology 2022-09-01 Thomas Fink

Age progression and regression refers to aesthetically render-ing a given face image to present effects of face aging and rejuvenation, respectively. Although numerous studies have been conducted in this topic, there are two major problems:…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Qi Li , Yunfan Liu , Zhenan Sun

The problem of prediction of a given time series is examined on the basis of recent nonlinear dynamics theories. Particular attention is devoted to forecast the amplitude and phase of one of the most common solar indicator activity, the…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Stefano Sello

Human aging is marked by a steady rise in the risk of dying with age-a process demographers call senescence. Over the past century, life expectancy has risen dramatically, but is this because we are aging slower, or simply starting it…

Applications · Statistics 2026-04-13 Silvio Cabral Patricio

As the global population continues to age, there is an increasing demand for ways to accurately quantify the biological processes underlying aging. Biological age, unlike chronological age, reflects an individual's physiological state,…

Quantitative Methods · Quantitative Biology 2025-08-29 Jared A Kushner , Mohit Pandey , Sandeep , S Kohli

Age progression is defined as aesthetically re-rendering the aging face at any future age for an individual face. In this work, we aim to automatically render aging faces in a personalized way. Basically, for each age group, we learn an…

Computer Vision and Pattern Recognition · Computer Science 2017-06-06 Xiangbo Shu , Jinhui Tang , Zechao Li , Hanjiang Lai , Liyan Zhang , Shuicheng Yan

In this paper, we aim to automatically render aging faces in a personalized way. Basically, a set of age-group specific dictionaries are learned, where the dictionary bases corresponding to the same index yet from different dictionaries…

Computer Vision and Pattern Recognition · Computer Science 2015-10-23 Xiangbo Shu , Jinhui Tang , Hanjiang Lai , Luoqi Liu , Shuicheng Yan

Existing approaches and datasets for face aging produce results skewed towards the mean, with individual variations and expression wrinkles often invisible or overlooked in favor of global patterns such as the fattening of the face.…

Computer Vision and Pattern Recognition · Computer Science 2021-03-12 Julien Despois , Frederic Flament , Matthieu Perrot

The relaxation dynamics of many disordered systems, such as structural glasses, proteins, granular materials or spin glasses, is not completely frozen even at very low temperatures. This residual motion leads to a change of the properties…

Soft Condensed Matter · Physics 2009-10-31 Walter Kob , Francesco Sciortino , Piero Tartaglia

We demonstrate aging behavior in a simple non-linear system. Our model is a chaotic map which generates deterministically sub-diffusion. Asymptotic behaviors of the diffusion process are described using aging continuous time random walks,…

Statistical Mechanics · Physics 2007-05-23 E. Barkai
‹ Prev 1 2 3 10 Next ›