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Although Machine Learning (ML) can be seen as a promising tool to improve clinical decision-making for supporting the improvement of medication plans, clinical procedures, diagnoses, or medication prescriptions, it remains limited by access…

Day-ahead operations involves a complex and computationally intensive optimization process to determine the generator commitment schedule and dispatch. The optimization process is a mixed-integer linear program (MILP) also known as…

Systems and Control · Electrical Eng. & Systems 2022-08-16 Arun Venkatesh Ramesh , Xingpeng Li

The adoption of machine learning (ML) and deep learning methods has revolutionized molecular medicine by driving breakthroughs in genomics, transcriptomics, drug discovery, and biological systems modeling. The increasing quantity,…

Multiple instance learning (MIL) has been extensively applied to whole slide histopathology image (WSI) analysis. The existing aggregation strategy in MIL, which primarily relies on the first-order distance (e.g., mean difference) between…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Yihang Chen , Tsai Hor Chan , Guosheng Yin , Yuming Jiang , Lequan Yu

In silico drug-target interaction (DTI) prediction is an important and challenging problem in biomedical research with a huge potential benefit to the pharmaceutical industry and patients. Most existing methods for DTI prediction including…

Machine Learning · Computer Science 2019-08-22 Qingyuan Feng , Evgenia Dueva , Artem Cherkasov , Martin Ester

In advancing discrete-based computational cancer models towards clinical applications, one faces the dilemma of how to deal with an ever growing amount of biomedical data that ought to be incorporated eventually in one form or another.…

Cell Behavior · Quantitative Biology 2008-06-26 Le Zhang , L. Leon Chen , Thomas S. Deisboeck

Machine learning (ML) has shown great promise for revolutionizing a number of areas, including healthcare. However, it is also facing a reproducibility crisis, especially in medicine. ML models that are carefully constructed from and…

Machine Learning · Computer Science 2024-09-16 Rongguang Wang , Guray Erus , Pratik Chaudhari , Christos Davatzikos

This research conducted a systematic review of the literature on machine learning (ML)-based methods in the context of Continuous Integration (CI) over the past 22 years. The study aimed to identify and describe the techniques used in…

Software Engineering · Computer Science 2023-07-18 Ali Kazemi Arani , Triet Huynh Minh Le , Mansooreh Zahedi , Muhammad Ali Babar

Atomistic simulations of multi-component systems require accurate descriptions of interatomic interactions to resolve details in the energy of competing phases. A particularly challenging case are topologically close-packed (TCP) phases…

With the development of deep learning, Deep Metric Learning (DML) has achieved great improvements in face recognition. Specifically, the widely used softmax loss in the training process often bring large intra-class variations, and feature…

Computer Vision and Pattern Recognition · Computer Science 2018-05-02 Bowen Wu , Huaming Wu , Monica M. Y. Zhang

Hit identification is a central challenge in early drug discovery, traditionally requiring substantial experimental resources. Recent advances in artificial intelligence, particularly large language models (LLMs), have enabled virtual…

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

Optimizing black-box functions is a fundamental problem in science and engineering. To solve this problem, many approaches learn a surrogate function that estimates the underlying objective from limited historical evaluations. Large…

Machine Learning · Computer Science 2025-10-23 Tung Nguyen , Aditya Grover

The explosion of digital data has created multiple opportunities for organizations and individuals to leverage machine learning (ML) to transform the way they operate. However, the shortage of experts in the field of machine learning --…

Machine Learning · Computer Science 2019-11-21 Doron Laadan , Roman Vainshtein , Yarden Curiel , Gilad Katz , Lior Rokach

Person re-identification (ReID) is an important task in computer vision. Recently, deep learning with a metric learning loss has become a common framework for ReID. In this paper, we also propose a new metric learning loss with hard sample…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 Qiqi Xiao , Hao Luo , Chi Zhang

Synthesis of advanced inorganic materials with minimum number of trials is of paramount importance towards the acceleration of inorganic materials development. The enormous complexity involved in existing multi-variable synthesis methods…

Materials Science · Physics 2020-11-02 Bijun Tang , Yuhao Lu , Jiadong Zhou , Han Wang , Prafful Golani , Manzhang Xu , Quan Xu , Cuntai Guan , Zheng Liu

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Artificial intelligence (AI) techniques are widely applied in the life sciences. However, applying innovative AI techniques to understand and deconvolute biological complexity is hindered by the learning curve for life science scientists to…

Artificial Intelligence · Computer Science 2024-03-28 Nisha Pillai , Athish Ram Das , Moses Ayoola , Ganga Gireesan , Bindu Nanduri , Mahalingam Ramkumar

In the computational prediction of chemical compound properties, molecular descriptors and fingerprints encoded to low dimensional vectors are used. The selection of proper molecular descriptors and fingerprints is both important and…

Machine Learning · Computer Science 2020-10-23 Sangrak Lim , Yong Oh Lee

A novel technique using machine learning (ML) to reduce the computational cost of evaluating lattice quantum chromodynamics (QCD) observables is presented. The ML is trained on a subset of background gauge field configurations, called the…

High Energy Physics - Lattice · Physics 2019-07-24 Boram Yoon , Tanmoy Bhattacharya , Rajan Gupta