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Diffusion-weighted magnetic resonance imaging (dMRI) is the only non-invasive tool for studying white matter tracts and structural connectivity of the brain. These assessments rely heavily on tractography techniques, which reconstruct…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Weide Liu , Camilo Calixto , Simon K. Warfield , Davood Karimi

Deep learning models generating structural brain MRIs have the potential to significantly accelerate discovery of neuroscience studies. However, their use has been limited in part by the way their quality is evaluated. Most evaluations of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Jiaqi Wu , Wei Peng , Binxu Li , Yu Zhang , Kilian M. Pohl

Functional MRI (fMRI) is crucial for studying brain function and diagnosing neurological disorders. However, existing analysis methods suffer from reproducibility and transferability challenges due to complex preprocessing pipelines and…

The cerebellar grey matter morphology is an important feature to study neurodegenerative diseases such as Alzheimer's disease or Down's syndrome. Its volume or thickness is commonly used as a surrogate imaging biomarker for such diseases.…

Computer Vision and Pattern Recognition · Computer Science 2021-07-28 Da Ma , Manuel J. Cardoso , Maria A. Zuluaga , Marc Modat , Nick. Powell , Frances Wiseman , Victor Tybulewicz , Elizabeth Fisher , Mark. F. Lythgoe , Sebastien Ourselin

In this paper, we describe our method for classification of brain magnetic resonance (MR) images into different abnormalities and healthy classes based on the deep neural network. We propose our method to detect high and low-grade glioma,…

Computer Vision and Pattern Recognition · Computer Science 2017-08-18 Mina Rezaei , Haojin Yang , Christoph Meinel

Diffusion magnetic resonance imaging (dMRI) provides critical insights into the microstructural and connectional organization of the human brain. However, the availability of high-field, open-access datasets that include raw k-space data…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Shanshan Wang , Shoujun Yu , Jian Cheng , Sen Jia , Changjun Tie , Jiayu Zhu , Haohao Peng , Yijing Dong , Jianzhong He , Fan Zhang , Yaowen Xing , Xiuqin Jia , Qi Yang , Qiyuan Tian , Hua Guo , Guobin Li , Hairong Zheng

Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Shaorong Zhang , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Jose-Luis Ambite , Paul M. Thompson , Greg Ver Steeg

Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) represent versatile tools with diverse applications spanning physics, chemistry, geology, and medical science. This comprehensive review explores the foundational…

Medical Physics · Physics 2024-03-07 Islam G. Ali

Magnetic Resonance Imaging (MRI) has become one of the most important tools to screen humans in medicine, virtually every modern hospital is equipped with an NMR tomograph. The potential of NMR in 3D imaging tasks is by far greater, but…

Soft Condensed Matter · Physics 2018-09-14 Ralf Stannarius

The dependence of the diffusion MRI signal on the diffusion time carries signatures of restricted diffusion and exchange. Here we seek to highlight these signatures in the human brain by performing experiments using free gradient waveforms…

The development of foundation models for brain MRI depends critically on the scale, diversity, and consistency of available data, yet systematic assessments of these factors remain scarce. In this study, we analyze 54 publicly accessible…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Minh Sao Khue Luu , Margaret V. Benedichuk , Ekaterina I. Roppert , Roman M. Kenzhin , Bair N. Tuchinov

Neuro-oncological surgery is the primary brain cancer treatment, yet it faces challenges with gliomas due to their invasiveness and the need to preserve neurological function. Hence, radical resection is often unfeasible, highlighting the…

MRI provides a unique non-invasive window into the brain, yet is limited to millimeter resolution, orders of magnitude coarser than cell dimensions. Here we show that diffusion MRI is sensitive to the micrometer-scale variations in axon…

Medical Physics · Physics 2020-07-10 Hong-Hsi Lee , Antonios Papaioannou , Sung-Lyoung Kim , Dmitry S. Novikov , Els Fieremans

Brain-mapping techniques have proven to be vital in understanding the molecular, cellular, and functional mechanisms of the brain. Normal anatomical imaging can provide structural information on certain abnormalities in the brain. However…

Emerging Technologies · Computer Science 2013-01-03 Nivedita Daimiwal , M. Sundhararajan , Revati Shriram

Generative models based on deep learning have shown significant potential in medical imaging, particularly for modality transformation and multimodal fusion in MRI-based brain imaging. This study introduces GM-LDM, a novel framework that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Hu Xu , Yang Jingling , Jia Sihan , Bi Yuda , Calhoun Vince

Understanding the operation of biological and artificial networks remains a difficult and important challenge. To identify general principles, researchers are increasingly interested in surveying large collections of networks that are…

Machine Learning · Statistics 2022-01-14 Alex H. Williams , Erin Kunz , Simon Kornblith , Scott W. Linderman

Diffusion-weighted Magnetic Resonance Imaging (dMRI) is increasingly used to study the fetal brain in utero. An important computation enabled by dMRI is streamline tractography, which has unique applications such as tract-specific analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Camilo Calixto , Camilo Jaimes , Matheus D. Soldatelli , Simon K. Warfield , Ali Gholipour , Davood Karimi

Deep learning analyses have offered sensitivity leaps in detection of cognitive states from functional MRI (fMRI) measurements across the brain. Yet, as deep models perform hierarchical nonlinear transformations on their input, interpreting…

Signal Processing · Electrical Eng. & Systems 2023-07-20 Hasan Atakan Bedel , Tolga Çukur

The purpose of this study is to present and compare three denoising diffusion probabilistic models (DDPMs) that generate 3D $T_1$-weighted MRI human brain images. Three DDPMs were trained using 80,675 image volumes from 42,406 subjects…

Image and Video Processing · Electrical Eng. & Systems 2025-11-03 Samuel W. Remedios , Aaron Carass , Jerry L. Prince , Blake E. Dewey

Disease in the brain is often associated with subtle, spatially diffuse, or complex tissue changes that may lie beneath the level of gross visual inspection, even on magnetic resonance imaging (MRI). Unfortunately, current computer-assisted…

Computer Vision and Pattern Recognition · Computer Science 2017-05-16 Shinjini Kundu , Soheil Kolouri , Kirk I Erickson , Arthur F Kramer , Edward McAuley , Gustavo K Rohde
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