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Small volume nuclear magnetic resonance spectroscopy (NMR) has recently made considerable progress due to rapid developments in the field of quantum sensing using nitrogen vacancy (NV) centers. These optically active defects in the diamond…

Quantum Physics · Physics 2021-11-19 Fleming Bruckmaier , Karl Briegel , Dominik B. Bucher

Nuclear magnetic resonance spectroscopy with solid-state spin sensors is a promising pathway for the detection of nuclear spins at the micro- and nanoscale. Although many nanoscale experiments rely on a single sensor spin for the detection…

Nuclear magnetic resonance (NMR) and nuclear quadrupole resonance (NQR) spectroscopy of bulk quantum materials have provided insight into phenomena such as quantum phase criticality, magnetism, and superconductivity. With the emergence of…

Advances in sensing devices that utilize nitrogen-vacancy (NV) center ensembles in diamond are driving progress in microscale nuclear magnetic resonance spectroscopy. Utilizing quantum sensing techniques in the high-field regime…

Quantum Physics · Physics 2025-10-22 Ainitze Biteri-Uribarren , Ana Martin , Jorge Casanova

Single-cell analysis can unravel functional heterogeneity within cell populations otherwise obscured by ensemble measurements. However, non-invasive techniques that probe chemical entities and their dynamics are still lacking. This…

Applied Physics · Physics 2023-06-14 Nick Ruben Neuling , Robin Derek Allert , Dominik Benjamin Bucher

Nuclear magnetic resonance (NMR) spectroscopy provides unparalleled access to molecular structure and dynamics but is traditionally limited by weak signal strength, requiring large sample volumes and high magnetic fields. Here, we…

Applied Physics · Physics 2026-04-29 Dileep Singh , Riley W. Hooper , Christoph Findler , Utsab Banerjee , Dominik B. Bucher

We demonstrate nuclear magnetic resonance (NMR) spectroscopy of picoliter-volume solutions with a nanostructured diamond chip. Using optical interferometric lithography, diamond surfaces were nanostructured with dense, high-aspect-ratio…

Mesoscale and Nanoscale Physics · Physics 2017-11-01 P. Kehayias , A. Jarmola , N. Mosavian , I. Fescenko , F. M. Benito , A. Laraoui , J. Smits , L. Bougas , D. Budker , A. Neumann , S. R. J. Brueck , V. M. Acosta

Nitrogen vacancy (NV) color centers in diamond are a leading modality for both superresolution optical imaging and nanoscale magnetic field sensing. In this work, we solve the remaining key challenge of performing optical magnetic imaging…

The nitrogen-vacancy (NV) centre in diamond has emerged as a candidate to non-invasively hyperpolarise nuclear spins in molecular systems to improve the sensitivity of nuclear magnetic resonance (NMR) experiments. Several promising proof of…

Mesoscale and Nanoscale Physics · Physics 2021-05-26 A. J. Healey , L. T. Hall , G. A. L. White , T. Teraji , M. -A. Sani , F. Separovic , J. -P. Tetienne , L. C. L. Hollenberg

We perform sensitive nuclear magnetic resonance (NMR) with spin ensembles which are polarized by nitrogen vacancy centers (NV centers) in diamond at room-temperature. With a near shot-noise-limited photoluminescence detection and a highly…

A diamond-based sensor utilizing nitrogen-vacancy (NV) center ensembles permits the analysis of micron-sized samples through NMR techniques at room temperature. Current efforts are directed towards extending the operating range of NV…

Quantum Physics · Physics 2024-10-07 P. Alsina-Bolívar , A. Biteri-Uribarren , C. Munuera-Javaloy , J. Casanova

Characterization of the molecular properties of surfaces under ambient or chemically reactive conditions is a fundamental scientific challenge. Moreover, many traditional analytical techniques used for probing surfaces often lack dynamic or…

Single-molecule technology stands as a powerful tool, enabling the characterization of intricate structural and dynamic information that would otherwise remain concealed within the averaged behaviors of numerous molecules. This technology…

Quantum Physics · Physics 2025-01-08 Jiangfeng Du , Fazhan Shi , Xi Kong , Fedor Jekezko , Jörg Wrachtrup

The nitrogen vacancy (NV) color center in diamond is an enormously important platform for the development of quantum sensors, including for single spin and single molecule NMR. Detection of weak single-spin signals is greatly enhanced by…

Quantum Physics · Physics 2017-05-29 J. E. Lang , J. Casanova , Z. -Y. Wang , M. B. Plenio , T. S. Monteiro

Nano-NMR spectroscopy with nitrogen-vacancy centers holds the potential to provide high resolution spectra of minute samples. This is likely to have important implications for chemistry, medicine and pharmaceutical engineering. One of the…

Quantum Physics · Physics 2020-06-23 Daniel Cohen , Ramil Nigmatullin , Matan Eldar , Alex Retzker

Quantum sensors based on the nitrogen-vacancy (NV) centre in diamond are rapidly advancing from scientific exploration towards the first generation of commercial applications. While significant progress has been made in developing suitable…

Nitrogen vacancy (NV) centers in diamond are atom-scale defects with long spin coherence times that can be used to sense magnetic fields with high sensitivity and spatial resolution. Typically, the magnetic field projection at a single…

The application of magnetic resonance (MR) spectroscopy at progressively smaller length scales may eventually permit "chemical imaging" of spins at the surfaces of materials and biological complexes. In particular, the negatively charged…

Mesoscale and Nanoscale Physics · Physics 2015-06-18 Hai-Jing Wang , Chang S. Shin , Scott J. Seltzer , Claudia E. Avalos , Alexander Pines , Vikram S. Bajaj

Individual, luminescent point defects in solids so called color centers are atomic-sized quantum systems enabling sensing and imaging with nanoscale spatial resolution. In this overview, we introduce nanoscale sensing based on individual…

Mesoscale and Nanoscale Physics · Physics 2017-05-11 Ettore Bernardi , Richard Nelz , Selda Sonusen , Elke Neu

Diamond-based quantum sensors have enabled high-resolution NMR spectroscopy at the microscale in scenarios where fast molecular motion averages out dipolar interactions among target nuclei. However, in samples with low-diffusion, ubiquitous…

Quantum Physics · Physics 2025-08-26 Carlos Munuera-Javaloy , Ander Tobalina , Jorge Casanova